Pulmonary Plasma Cell Granuloma

A tumor-like inflammatory lesion of the lung that is composed of PLASMA CELLS and fibrous tissue. It is also known as an inflammatory pseudotumor, often with calcification and measuring between 2 and 5 cm in diameter.

Also Known As:

Plasma Cell Granuloma, Pulmonary; Inflammatory Pseudotumor, Pulmonary; Inflammatory Pulmonary Pseudotumor; Plasma Cell Granuloma of Lung; Pseudotumor, Inflammatory, Pulmonary; Pseudotumor, Pulmonary Inflammatory; Pulmonary Granuloma, Plasma Cell; Pulmonary Inflammatory Pseudotumor; Pulmonary Pseudotumor, Inflammatory; Inflammatory Pseudotumors, Pulmonary; Inflammatory Pulmonary Pseudotumors; Pulmonary Inflammatory Pseudotumors; Pulmonary Pseudotumors, Inflammatory; Granuloma, Plasma Cell, Pulmonary; Inflammatory Pseudotumor of Lung

Networked: 14 relevant articles (2 outcomes, 0 trials/studies)

Relationship Network

Disease Context: Research Results

Respiratory Tract Diseases: 6015
- Lung Diseases: 22246
  - Pulmonary Plasma Cell Granuloma: 14

Related Diseases

1.	Neoplasms (Cancer)
2.	Benign Fibrous Histiocytoma (Dermatofibroma)
3.	Tuberculosis (Tuberculoses)
4.	Thymoma (Thymic Carcinoma)
5.	Stomach Neoplasms (Stomach Cancer)

Experts

1.	Bai, Jing: 1 article (10/2019)
2.	Bin, Yan-Fei: 1 article (10/2019)
3.	He, Zhi-Yi: 1 article (10/2019)
4.	Li, Mei-Hua: 1 article (10/2019)
5.	Liang, Yi: 1 article (10/2019)
6.	Liang, Yu-Ji: 1 article (10/2019)
7.	Sun, Xue-Jiao: 1 article (10/2019)
8.	Wu, Lu-Jia: 1 article (10/2019)
9.	Zhang, Jian-Quan: 1 article (10/2019)
10.	Zhong, Xiao-Ning: 1 article (10/2019)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Pulmonary Plasma Cell Granuloma:

1.	Adrenal Cortex Hormones (Corticosteroids)IBA 05/01/1994 - "As middle-dosage corticosteroid therapy is not cytotoxic, it is useful for the treatment of pulmonary plasma cell granuloma, especially in multifocal, unresectable, and/or relapsing cases." 05/01/1994 - "Pulmonary plasma cell granuloma improves with corticosteroid therapy." 10/01/2019 - "Lung tissue samples were obtained from patients with COP (n = 9), IPF (n = 8), pulmonary abscesses (n = 7), or pulmonary inflammatory pseudotumors (n = 6) before corticosteroid treatment, as well as from control subjects (n = 10). " 09/01/2016 - "We present a proven case of pulmonary inflammatory pseudotumor that illustrates the (18)F-FDG PET/CT imaging features of this "great mimicker of malignancy" both at initial diagnosis and during early monitoring of corticosteroid therapy, which is advocated as the first-line treatment. " 01/01/2018 - "Pulmonary inflammatory pseudotumor causing lung collapse responding to corticosteroid therapy."
2.	CateninsIBA 02/20/2006 - "Expression of E-cadherin, β-catenin and p120 ctn was detected in 25 cases of PSH samples and 8 cases of pulmonary inflammatory pseudotumor samples by immunohistochemistry. "
3.	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 09/01/2016 - "18F-FDG PET/CT Imaging Features of IgG4-Related Pulmonary Inflammatory Pseudotumor at Initial Diagnosis and During Early Treatment Monitoring."
4.	Cadherins (E-Cadherin)IBA 02/20/2006 - "Expression of E-cadherin, β-catenin and p120 ctn was detected in 25 cases of PSH samples and 8 cases of pulmonary inflammatory pseudotumor samples by immunohistochemistry. "
5.	SteroidsIBA 03/01/1991 - "It is conceivable that steroid therapy is an effective therapy for pulmonary plasma cell granuloma, especially multifocal and relapsing cases."
6.	Immunoglobulins (Immunoglobulin)IBA 07/01/2013 - "Case report of anti-transcription intermediary factor-1-γ/α antibody-positive dermatomyositis associated with gastric cancer and immunoglobulin G4-positive pulmonary inflammatory pseudotumor."
7.	Immunoglobulin G (IgG)IBA 11/01/2008 - "[A case of pulmonary inflammatory pseudotumor accompanied with increased serum immunoglobulin G levels and autoimmune pancreatitis]."
8.	Carcinoembryonic AntigenIBA 03/01/2003 - "We report a rare case of pulmonary inflammatory pseudotumor associated with rapid growth and elevated serum carcinoembryonic antigen (CEA). " 03/01/2003 - "Pulmonary inflammatory pseudotumor with rapid growth and serum carcinoembryonic antigen elevation."
9.	Delta CateninIBA 02/20/2006 - "Expression of E-cadherin, β-catenin and p120 ctn was detected in 25 cases of PSH samples and 8 cases of pulmonary inflammatory pseudotumor samples by immunohistochemistry. "

Therapies and Procedures

1.	Therapeutics 08/01/2012 - "In addition, pulmonary inflammatory pseudotumors present a low malignancy with good response to surgical treatment as well as to pharmacological therapy, although to a lesser degree. " 05/01/1994 - "As middle-dosage corticosteroid therapy is not cytotoxic, it is useful for the treatment of pulmonary plasma cell granuloma, especially in multifocal, unresectable, and/or relapsing cases." 05/01/1994 - "Pulmonary plasma cell granuloma improves with corticosteroid therapy." 03/01/1991 - "It is conceivable that steroid therapy is an effective therapy for pulmonary plasma cell granuloma, especially multifocal and relapsing cases." 09/01/2016 - "We present a proven case of pulmonary inflammatory pseudotumor that illustrates the (18)F-FDG PET/CT imaging features of this "great mimicker of malignancy" both at initial diagnosis and during early monitoring of corticosteroid therapy, which is advocated as the first-line treatment. "
2.	Thoracotomy 01/01/2002 - "Of three patients with suspected malignancy, one was diagnosed as tuberculosis by cervical mediastinoscopy and the other two as lymphoma and pulmonary inflammatory pseudotumor by thoracoscopy and thoracotomy. " 12/20/2001 - "2001, 40 patients ( male 26, female 14, with age of 20-79 years old) underwent thoracotomies, in which 15 had lung cancer, 1 carcinoid, 1 infectious cyst of lung, 2 pulmonary inflammatory pseudotumor, 2 thymoma, and 19 esophageal carcinoma. "
3.	Pneumonectomy (Lung Volume Reduction) 01/01/2010 - "While undergoing an intrapericardial pneumonectomy for a massive right pulmonary inflammatory pseudotumor that had invaded the mediastinum, an 18-year-old woman experienced a nearly fatal iatrogenic complication. " 09/01/1987 - "A child had a pulmonary plasma cell granuloma/fibrous histiocytoma that recurred after lobectomy in 1952 and required pneumonectomy in 1953, at which time it extended into the mediastinum at the pulmonary hilus. "