Antimutagenic Agents (Antimutagens)

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29 relevant articles (0 outcomes, 4 trials/studies) found for this Bio-Agent

Description: Agents that reduce the frequency or rate of spontaneous or induced mutations independently of the mechanism involved.

Also Known As:

Antimutagens; Anti-Mutagenic Agents; Agents, Anti-Mutagenic; Agents, Antimutagenic; Anti Mutagenic Agents

Bio-Agent Context: Research Results

Chemical Actions and Uses

Pharmacologic Actions: 50

Physiological Effects of Drugs: 1

Protective Agents: 216

Antimutagenic Agents: 29

Specialty Uses of Chemicals

Protective Agents: 216

Antimutagenic Agents: 29

Experts

1.	P, Rauko: 1 article (01/2008)
2.	Korolenko, T A: 1 article (01/2008)
3.	Slamenova, D: 1 article (01/2008)
4.	Babincova, M: 1 article (01/2008)
5.	Kogan, G: 1 article (01/2008)
6.	D, Slamenova: 1 article (01/2008)
7.	M, Babincova: 1 article (01/2008)
8.	M, Pajtinka: 1 article (01/2008)
9.	E, Miadokova: 1 article (01/2008)
10.	Pajtinka, M: 1 article (01/2008)

Related Diseases

1.	Neoplasms (Cancer) 01/01/1996 - "The importance of antimutagenesis studies in cancer prevention is reported and a review of the basic mechanisms operative in antimutagenesis, including some data on known antimutagens, is made." 05/20/2004 - "Dietary antimutagens may provide a means of slowing progression toward cancer, and be more acceptable to the population" 05/20/2004 - "Dietary cancer and prevention using antimutagens." 03/01/2004 - "vellereus can be considered as a natural source of antimutagens with potential pharmacological applications in cancer prevention." 06/04/2003 - "Natural antimutagens may prevent cancer and are therefore of great interest to oncologists and the public at large" Get all the results and reference details, order at left...
2.	Genomic Instability 01/01/1997 - "Recommended chemoprevention strategies based on these mechanisms are (1) early diagnosis and treatment of genomic instability before the appearance of intraepithelial neoplasia, i.e., during the "predysplastic" or "premorphologic" phase, (2) development of multiple agents that block intralesional proliferation at steps along the "command" pathways of mitotic signal transduction and along the "execute" pathways of synthesis of daughter cell components, (3) development of nontoxic antiinflammatory agents, antioxidants, antimutagens, and proapoptotics, (4) avoidance of "clonal escape" through use of drug combinations, and (5) use of computer-assisted quantitative image analysis to assay modulation of surrogate endpoints in chemoprevention clinical trials." Get all the results and reference details, order at left...
3.	Prostatic Intraepithelial Neoplasia 01/01/1997 - "Over 40 short-term clinical trials are in progress, testing the following classes of agents on precancerous lesions in the different major organ systems: antimutagens (N-acetylcysteine, oltipraz), antiproliferatives (difluoromethylornithine, dehydroepiandrosterone, selenomethionine), antioxidants (vitamin E, curcumin), anti-inflammatories (aspirin, piroxicam, ibuprofen, sulindac sulfone) and hormonally active agents (tamoxifen in breast ductal carcinoma in situ and finasteride in prostatic intraepithelial neoplasia)" Get all the results and reference details, order at left...
4.	Breast Ductal Carcinoma 01/01/1997 - "Over 40 short-term clinical trials are in progress, testing the following classes of agents on precancerous lesions in the different major organ systems: antimutagens (N-acetylcysteine, oltipraz), antiproliferatives (difluoromethylornithine, dehydroepiandrosterone, selenomethionine), antioxidants (vitamin E, curcumin), anti-inflammatories (aspirin, piroxicam, ibuprofen, sulindac sulfone) and hormonally active agents (tamoxifen in breast ductal carcinoma in situ and finasteride in prostatic intraepithelial neoplasia)" Get all the results and reference details, order at left...
5.	Chromosome Aberrations (Chromosome Abnormalities) 06/01/1990 - "In vivo effects of single or combined dietary antimutagens on mutagen-induced chromosomal aberrations." 03/01/1994 - "In cultures of lymphocytes from 12 healthy donors and 12 patients with nettle-rash (NR) the anticlastogenic effect of the antimutagens WR-2721 (WR), bemitil (BM), tomerzol (TM) and interferon (IF) on the induction of chromosomal aberrations by photrin (PT) and dioxidine (DX) was investigated" Get all the results and reference details, order at left...
16 Diseases and 29 more articles analyzed in the Research Interface, order at left...

Related Drugs and Biologics

1.	Antioxidants
2.	Anti-Inflammatory Agents (Anti-Inflammatories)
3.	Finasteride (Propecia)
4.	Biological Markers (Surrogate Marker)
5.	Vitamin E
6.	Tamoxifen
7.	Selenomethionine (Sethotope)
8.	Piroxicam (Feldene)
9.	Ibuprofen (Motrin)
10.	Drug Combinations
38 Drugs and Important Bio-Agents and 19 more articles analyzed in the Research Interface, order at left...

Related Therapies and Procedures

1.	Chemoprevention
2.	Aftercare (After-Treatment)
2 Therapies and Procedures and 4 more articles analyzed in the Research Interface, order at left...

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