|1.||Asthma (Bronchial Asthma)
|5.||Chronic Obstructive Pulmonary Disease (COPD)
|1.||Habre, Walid: 7 articles (01/2014 - 07/2006)|
|2.||Kline, Joel N: 6 articles (03/2009 - 05/2002)|
|3.||Stelmach, Iwona: 6 articles (01/2003 - 01/2002)|
|4.||Kuna, Piotr: 6 articles (01/2003 - 01/2002)|
|5.||Ciprandi, Giorgio: 5 articles (11/2014 - 02/2006)|
|6.||Groeben, H: 5 articles (03/2007 - 01/2000)|
|7.||Cirillo, Ignazio: 4 articles (11/2014 - 02/2006)|
|8.||von Ungern-Sternberg, Britta S: 4 articles (06/2014 - 11/2009)|
|9.||Peták, Ferenc: 4 articles (01/2014 - 07/2006)|
|10.||Bodzenta-Lukaszyk, Anna: 4 articles (12/2010 - 01/2007)|
|1.||Methacholine Chloride (Methacholine)FDA Link
07/01/1993 - "The results show in both groups a mild but statistically not significant reduction of the provocation reaction in the inhalative methacholine provocation test in the sense of an improvement in bronchial hyperreactivity. "
02/15/2005 - "Histopathological examination revealed Pw immunization reduced the severity of airway pathology and decreased bronchial hyperreactivity to methacholine exposure. "
07/01/1997 - "Although this study disclosed no acute or delayed asthmatic symptoms or deterioration of pulmonary function detected by using conventional spirometry, methacholine inhalation before and after cow milk challenge may be more sensitive for evaluation of cow milk-induced bronchial hyperreactivity."
11/01/1994 - "All patients showed bronchial hyperreactivity to inhaled methacholine before the study. "
07/01/1993 - "We examined 20 patients in whom bronchial hyperreactivity and positive inhalative methacholine provocation test (dosage-effect curve) had been known for at least 3 months at the time of study. "
|2.||Histamine (Histamine Dihydrochloride)FDA Link
06/01/2004 - "In conclusion, ECT induced a significantly greater bronchial reaction in patients with AA and bronchial hyperreactivity to histamine than in patients with AR and bronchial normoreactivity to histamine and controls. "
03/01/2003 - "Histamine provocations were performed at the age of 7 years in the MAS cohort to determine bronchial hyperreactivity; in the Freiburg study population a standardized exercise-induced decrease in FEV1 was evaluated. "
12/01/1994 - "Therefore, the objective of the present study was to assess the bronchopulmonary effects in asthmatic patients who showed a moderate to severe bronchial hyperreactivity towards histamine (PC20 FEV1 < or = 1 mg/ml). "
04/01/1986 - "Bronchial provocation studies with histamine demonstrated significant bronchial hyperreactivity in 0.5% (1 in 195) rural and 1.7% (1 in 59) urban children, rates which were significantly lower than those observed in corresponding adult populations (7%). "
01/01/1982 - "At the department of allergology is Göteborg clinical models have been developed for studies of the allergen-induced and histamine- (and metacholine-) induced bronchial hyperreactivity. "
|3.||Immunoglobulin E (IgE)IBA
03/01/2005 - "SLIT seems to be effective in ameliorating clinical symptoms, drug consumption and bronchial hyperreactivity, and results in downregulation of Der-p-1-specific IgE production. "
03/01/2000 - "On the basis of studies with animal models, the gene for the low-affinity receptor for immunoglobulin E (IgE) (FCER2, CD23) has been implicated as a candidate for IgE-mediated allergic diseases and bronchial hyperreactivity, or related traits. "
02/01/1998 - "Linkage studies have provided evidence for the presence of gene(s) in the 5q cytokine cluster region which control total serum immunoglobulin E (IgE) concentration, and bronchial hyperreactivity (BHR). "
01/01/2011 - "Of these women, 2,873 had lung function measurements, 2,136 had measurements of bronchial hyperreactivity, and 2,743 had IgE measurements. "
07/01/2010 - "On day 14, mice were killed for the evaluation of OVA-specific IgE, cytokine production by mediastinal lymph node (MLN) cells and bronchial hyperreactivity (BHR) to inhaled metacholine. "
|4.||Albuterol (Salbutamol)FDA LinkGeneric
06/01/1994 - "None of the subjects in the control group improved their baseline FEV1/VC% to salbutamol, but three showed bronchial hyperreactivity similar to those in group A. "
09/01/2006 - "The continued use of racemic albuterol, which contains a mixture of R-albuterol and S-albuterol, has been questioned because of data from preclinical and clinical studies suggesting that S-albuterol causes proinflammatory effects and may increase bronchial hyperreactivity. "
10/01/1997 - "Further dose ranging studies are required at steady state to evaluate the pharmacokinetics of R- and S-salbutamol and their relative effects on bronchial hyperreactivity when given on a regular basis to asthmatic subjects."
10/01/1997 - "Data from animal and human studies suggest that the S-isomer, whilst contributing no bronchodilator activity, may induce increased bronchial hyperreactivity and may explain the adverse effects of regular racemic salbutamol on asthmatic disease control. "
12/01/1994 - "Moreover, it had to be established to what extent the bronchial responsiveness to inhaled salbutamol was retained and whether pulmonary effects were related to the severity of bronchial hyperreactivity. "
|5.||Budesonide (Pulmicort)FDA LinkGeneric
08/01/2012 - "Both TRP and budesonide significantly ameliorated functional and histological OVA-induced bronchial hyperreactivity. "
01/01/1988 - "In a double-blind study of 2 parallel groups of 15 allergic asthmatic patients each, we investigated whether treatment with inhaled budesonide has a dose- and time-dependent effect on the degree of bronchial hyperreactivity. "
01/01/1988 - "Dosage and time effects of inhaled budesonide on bronchial hyperreactivity."
06/07/1986 - "Budesonide seems to influence and mitigate bronchial hyperreactivity in the responder group."
11/01/1998 - "The aim of the present study was to examine the efficacy of low-dose inhaled budesonide (BUD) administered via Turbuhaler once or twice daily on symptoms, lung function and bronchial hyperreactivity in children with mild asthma. "
|6.||Nedocromil (Alocril)FDA Link
03/01/1995 - "Nedocromil sodium is a novel anti-inflammatory agent that has been demonstrated to significantly improve pulmonary function and decrease bronchial hyperreactivity in asthmatic patients. "
06/01/1993 - "In conclusion, the effect of nedocromil sodium in the prevention of EIB may be dose-dependent in relation to the degree of bronchial hyperreactivity or to interference of other factors."
12/01/1997 - "Nedocromil sodium can reduce the severity of asthmatic symptoms and nonspecific bronchial hyperreactivity at fog-induced challenge in children with stable, nonatopic asthma."
12/01/1997 - "We therefore investigated a possible effect of nedocromil sodium on bronchial hyperreactivity and asthmatic symptoms in a group of children receiving this drug for nonatopic asthma. "
12/01/1997 - "Effect of nedocromil sodium on bronchial hyperreactivity in children with nonatopic asthma."
|7.||Bronchodilator Agents (Bronchodilators)IBA
06/01/1993 - "Long-term studies showed that anti-inflammatory therapy is superior to bronchodilators for improving pulmonary function and decreasing bronchial hyperreactivity. "
06/01/2009 - "The response to bronchodilators in adults is not predictive of bronchial-hyperreactivity."
06/01/2008 - "Response to bronchodilators after exercise challenge predicts bronchial hyperreactivity."
03/01/1982 - "The mechanism of action of bronchodilators may be associated with modification of bronchial hyperreactivity."
10/01/1989 - "Prescribed pharmacotherapy should be based on the combination of symptoms, pulmonary function, bronchial hyperreactivity, and reversibility on the prescribed bronchodilators."
|8.||Beclomethasone (Beclometasone)FDA Link
01/01/1991 - "A statistically significant reduction in bronchial hyperreactivity (PC20-FEV1, 5.49 +/- 1.86 mg/mL) but no systemic side effects were observed after 2 months of treatment with beclomethasone dipropionate. "
06/01/1992 - "Dissociation of symptom scores and bronchial hyperreactivity: study in asthmatic children on long-term treatment with inhaled beclomethasone dipropionate."
01/01/1991 - "Effect of inhaled beclomethasone dipropionate on bronchial hyperreactivity in asthmatic children during maximal allergen exposure."
01/01/1982 - "The effect of beclomethasone diproprionate on bronchial hyperreactivity."
09/01/1984 - "Multiparametrical approach to fog-challenge-induced bronchial hyperreactivity in asthmatics--protective effects of salbutamol plus beclomethasone dipropionate."
05/01/2008 - "Persistent nonspecific bronchial hyperreactivity was associated with proinflammatory acting cytokines produced mainly by macrophages. "
01/01/1990 - "Cytokines and bronchial hyperreactivity."
03/17/2000 - "Allergic asthma is caused by the aberrant expansion in the lung of T helper cells that produce type 2 (TH2) cytokines and is characterized by infiltration of eosinophils and bronchial hyperreactivity. "
01/01/1990 - "The importance of cytokines in the pathogenesis of bronchial hyperreactivity and asthma has been reviewed in this paper."
01/01/2013 - "The upregulation of these cytokines is likely to play a proinflammatory role in H1N1 virus infection and may contribute to airway inflammation and bronchial hyperreactivity in these patients."
|10.||Ipratropium (Ipratropium Bromide)FDA LinkGeneric
04/01/1997 - "The bronchial hyperreactivity to MCh was completely blocked by pretreatment inhalation of ipratropium bromide, suggesting the muscarinic receptor-mediated mechanism. "
01/01/1988 - "Lack of correlation between the grade of methacholine-induced bronchial hyperreactivity and ipratropium bronchodilation in asthmatics."
01/01/1984 - "[Effect of SCH 1000 on bronchial hyperreactivity compared to that of fenoterol]."
09/26/1980 - "[Suppression of non-specific bronchial hyperreactivity by DSCG (Disodium cromoglycate) and ipratropium bromide (author's transl)]."
05/01/1992 - "Efficacy of salbutamol and ipratropium bromide in decreasing bronchial hyperreactivity in children with cystic fibrosis."
01/24/2000 - "2. To estimate the overall efficacy of allergen specific immunotherapy upon asthmatic symptoms, medication requirements, lung function, nonspecific bronchial hyperreactivity (BHR) and allergen specific BHR. "
11/01/2006 - "This immunotherapy modifies the natural course of the illness because it improves all clinical outcomes measured and prevents the worsening of specific bronchial hyperreactivity."
11/01/2004 - "Sublingual immunotherapy approximately halved the clinical scores and significantly reduced the bronchial hyperreactivity. "
11/01/2004 - "Some aspects of sublingual immunotherapy (SLIT) still need to be addressed: magnitude of the clinical efficacy, effect on the bronchial hyperreactivity adherence to treatment, preventive effect. "
01/01/2002 - "Changes in inflammatory and clinical parameters and in bronchial hyperreactivity asthmatic children sensitized to house dust mites following sublingual immunotherapy."
01/01/1981 - "Pharmacological rehabilitation is defined as a decrease of bronchial hyperreactivity and a stabilization of the bronchial reactivity after treatment with drugs possessing prophylactic and therapeutic properties. "
07/01/2002 - "The primary endpoint of this study was to determine changes in serum levels of inflammatory markers after treatment with formoterol; secondary endpoints included clinical efficacy and bronchial hyperreactivity. "
04/01/1985 - "Modification of bronchial hyperreactivity after treatment with sodium cromoglycate during pollen season."
04/01/2002 - "A study of the relationships between spirometric indices, airway inflammation, airway remodelling, and bronchial hyperreactivity (BHR) before and after treatment with high dose inhaled fluticasone propionate (FP 750 microg bd) was performed in a group of patients with relatively mild but symptomatic asthma. "
01/01/2002 - "After treatment with nedocromil, clinical symptoms improved significantly, IL-10 serum levels and bronchial hyperreactivity did not change significantly (p = 0.094 and p = 0.09 respectively). "
03/01/2007 - "Laser acupuncture and probiotics significantly decreased mean (standard deviation) weekly PFV as a measurement of bronchial hyperreactivity by -17.4% (14.2) in the TCM group vs. 2.2% (22.5) in the control group (p = 0.034). "
03/01/2007 - "In conclusion, this pilot study generates the hypothesis that the interactive treatment of lung and large intestine according to TCM by laser acupuncture and probiotics has a beneficial clinical effect on bronchial hyperreactivity in school age children with intermittent or mild persistent asthma and might be helpful in the prevention of acute respiratory exacerbations. "
|5.||Enteral Nutrition (Feeding, Tube)