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Neurofibromatosis 2 (Neurofibromatosis Type II)

An autosomal dominant disorder characterized by a high incidence of bilateral acoustic neuromas as well as schwannomas (NEURILEMMOMA) of other cranial and peripheral nerves, and other benign intracranial tumors including meningiomas, ependymomas, spinal neurofibromas, and gliomas. The disease has been linked to mutations of the NF2 gene (GENES, NEUROFIBROMATOSIS 2) on chromosome 22 (22q12) and usually presents clinically in the first or second decade of life.
Also Known As:
Neurofibromatosis Type II; Bilateral Acoustic Neurofibromatosis; Neurofibromatosis Type 2; Neurofibromatosis II; 2 Neurofibromatosis, Type; Familial Acoustic Neuroma; Type II Neurofibromatosis; Schwannoma, Acoustic, Bilateral; Acoustic Neurinoma, Bilateral; Acoustic Schwannomas, Bilateral; Familial Acoustic Neuromas; NF2 (Neurofibromatosis 2); Neurofibromatosis, Central NF2; Neurofibromatosis, Central, NF 2; Neurofibromatosis, Type 2; Neurofibromatosis, Type II; Acoustic Neurinomas, Bilateral; Acoustic Neurofibromatoses, Bilateral; Acoustic Neurofibromatosis, Bilateral; Acoustic Neuroma, Familial; Acoustic Neuromas, Familial; Acoustic Schwannoma, Bilateral; Bilateral Acoustic Neurinoma; Bilateral Acoustic Neurinomas; Bilateral Acoustic Neurofibromatoses; Bilateral Acoustic Schwannoma; Bilateral Acoustic Schwannomas; Central NF2 Neurofibromatoses; Central NF2 Neurofibromatosis; NF2s (Neurofibromatosis 2); Neurinoma, Bilateral Acoustic; Neurinomas, Bilateral Acoustic; Neurofibromatoses, Bilateral Acoustic; Neurofibromatoses, Central NF2; Neurofibromatoses, Type 2; Neurofibromatoses, Type II; Neurofibromatosis IIs; Neurofibromatosis, Bilateral Acoustic; Neuroma, Familial Acoustic; Neuromas, Familial Acoustic; Schwannoma, Bilateral Acoustic; Schwannomas, Bilateral Acoustic; Type 2 Neurofibromatoses; Type 2 Neurofibromatosis; Type II Neurofibromatoses; Neurofibromatosis, Acoustic, Bilateral; Neurofibromatosis, Central, NF2; Neuroma, Acoustic, Bilateral
Networked: 290 relevant articles (3 outcomes, 16 trials/studies) for this Disease, Comments

Relationship Network

Disease Context: Research Results

Related Diseases

1. Acoustic Neuroma (Acoustic Neurinoma)
2. Deafness (Deaf Mutism)
3. Neoplasms (Cancer)
4. Neurilemmoma (Schwannoma)
5. Meningioma (Meningiomas)

Experts

1. Gutmann, David H: 10 articles (03/2009 - 09/2002)
2. Giovannini, Marco: 9 articles (03/2009 - 08/2002)
3. Chang, Long-Sheng: 5 articles (01/2009 - 01/2002)
4. Otto, Steven R: 5 articles (12/2008 - 01/2003)
5. Brackmann, Derald E: 5 articles (12/2008 - 01/2003)
6. Scoles, Daniel R: 5 articles (01/2008 - 12/2002)
7. Sterkers, O: 5 articles (07/2007 - 01/2000)
8. Rey, A: 5 articles (07/2007 - 01/2000)
9. Bouccara, D: 5 articles (07/2007 - 01/2000)
10. Lee, Kweon-Haeng: 5 articles (12/2004 - 09/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Neurofibromatosis 2:
1. bevacizumabFDA Link
2. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
3. Neurofibromin 2 (Merlin)IBA
4. DNA (Deoxyribonucleic Acid)IBA
5. Genetic Markers (Genetic Marker)IBA
6. ParaffinIBA
7. Formaldehyde (Formol)IBA
8. SynteninsIBA
9. Secretogranin IIIBA
10. Chromogranin AIBA

Therapies and Procedures

1. Auditory Brain Stem Implants (Auditory Brainstem Implants)
2. Radiotherapy
3. Heterologous Transplantation (Xenotransplantation)
4. Cochlear Implantation
5. Auditory Brain Stem Implantation

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