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Benign Familial Pemphigus (Hailey Hailey Disease)

118  relevant articles (14 outcomes, 4 trials/studies) found for this Disease

Description: An autosomal dominantly inherited skin disorder characterized by recurrent eruptions of vesicles and BULLAE mainly on the neck, axillae, and groin. Mutations in the ATP2C1 gene (encoding the secretory pathway Ca2++/Mn2++ ATPase 1 (SPCA1)) cause this disease. It is clinically and histologically similar to DARIER DISEASE - both have abnormal, unstable DESMOSOMES between KERATINOCYTES and defective CALCIUM-TRANSPORTING ATPASES. It is unrelated to PEMPHIGUS VULGARIS though it closely resembles that disease.

Also Known As:
Hailey Hailey Disease; Pemphigus, Benign Familial; Familial Pemphigus, Benign; Familial Benign Chronic Pemphigus; Hailey-Hailey Disease

Relationship Network

Disease Context: Research Results

Related Diseases

1. Darier Disease (Darier's Disease)
2. Psoriasis (Pustulosis Palmaris et Plantaris)
3. Hidradenitis Suppurativa
4. Hidrocystoma
5. Gustatory Sweating (Frey's Syndrome)

Experts

1. Shimizu, H: 3 articles (01/2006 - 04/2000)
2. Akiyama, M: 3 articles (01/2006 - 04/2000)
3. Kellermayer, Richard: 2 articles (01/2006 - 12/2004)
4. Hakuno, M: 2 articles (07/2001 - 04/2000)
5. Wheelock, M J: 2 articles (07/2001 - 04/2000)
6. Nishikawa, T: 2 articles (07/2001 - 04/2000)
7. Bevins, A: 1 article (02/2008)
8. Hurd, D S: 1 article (02/2008)
9. Johnston, C: 1 article (02/2008)
10. Krekels, Gertruud: 1 article (01/2008)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Benign Familial Pemphigus:
1. Tacrolimus (Prograf)FDA Link
2. Botulinum Toxin Type A (Botox)FDA Link
3. HormonesIBA
4. Botulinum Toxins (Botulinum Toxin)IBA
5. Goserelin (Zoladex)FDA Link
6. AcitretinFDA Link
7. Penicillins (Penicillin)FDA Link
8. 1 alpha,24-dihydroxyvitamin D3 (Tacalcitol)IBA
9. Adenosine Triphosphatases (ATPase)IBA
10. Cadherins (E-Cadherin)IBA

Therapies and Procedures

1. Gas Lasers
2. Dermabrasion
3. Transplants (Transplant)
4. Solid-State Lasers
04/01/1999 - "Efficacy of erbium:YAG laser ablation in Darier disease and Hailey-Hailey disease."
Order ALL the reference details at left...
5. Cryosurgery

Best Treatments:
Research Summary Report
on Benign Familial Pemphigus
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