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Sp1 Transcription Factor

Promoter-specific RNA polymerase II transcription factor that binds to the GC box, one of the upstream promoter elements, in mammalian cells. The binding of Sp1 is necessary for the initiation of transcription in the promoters of a variety of cellular and viral GENES.
Also Known As:
Specificity Protein 1 Transcription Factor; Transcription Factor, Sp1
Networked: 168 relevant articles (0 outcomes, 15 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Xie, Keping: 9 articles (07/2008 - 12/2003)
2. Wei, Daoyan: 9 articles (07/2008 - 12/2003)
3. Wang, Liwei: 8 articles (07/2008 - 12/2003)
4. Yao, James: 7 articles (07/2008 - 12/2003)
5. Zhang, Jun: 6 articles (01/2013 - 04/2005)
6. Knappskog, Stian: 5 articles (09/2014 - 02/2011)
7. Lønning, Per E: 5 articles (09/2014 - 02/2011)
8. Ajani, Jaffer: 5 articles (02/2007 - 12/2003)
9. Hveem, Kristian: 4 articles (09/2014 - 02/2011)
10. Vatten, Lars: 4 articles (09/2014 - 02/2011)

Related Diseases

1. Neoplasms (Cancer)
2. Anoxia (Hypoxia)
3. Pancreatic Neoplasms (Pancreatic Cancer)
4. Stomach Neoplasms (Stomach Cancer)
5. Carcinoma (Carcinomatosis)

Related Drugs and Biologics

1. Transcription Factors (Transcription Factor)
2. Transforming Growth Factor beta (TGF-beta)
3. Epidermal Growth Factor Receptor (EGF Receptor)
4. NF-kappa B (NF-kB)
5. RNA (Ribonucleic Acid)
6. Pirenzepine
7. tebufenozide (Mimic)
8. resveratrol
9. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
10. Collagen Type I (Type I Collagen)

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)
2. Drug Therapy (Chemotherapy)