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Extracellular Matrix Proteins

Macromolecular organic compounds that contain carbon, hydrogen, oxygen, nitrogen, and usually, sulfur. These macromolecules (proteins) form an intricate meshwork in which cells are embedded to construct tissues. Variations in the relative types of macromolecules and their organization determine the type of extracellular matrix, each adapted to the functional requirements of the tissue. The two main classes of macromolecules that form the extracellular matrix are: glycosaminoglycans, usually linked to proteins (proteoglycans), and fibrous proteins (e.g., COLLAGEN; ELASTIN; FIBRONECTINS; and LAMININ).
Also Known As:
Matrix Protein, Extracellular; Matrix Proteins, Extracellular; Protein, Extracellular Matrix; Proteins, Extracellular Matrix; Extracellular Matrix Protein
Networked: 3148 relevant articles (32 outcomes, 198 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Chakrabarti, Subrata: 11 articles (03/2019 - 06/2003)
2. Frangogiannis, Nikolaos G: 8 articles (01/2021 - 01/2006)
3. Wang, Wei: 8 articles (01/2021 - 01/2011)
4. Bonaldo, Paolo: 8 articles (11/2020 - 04/2008)
5. Burgess, Janette K: 7 articles (12/2021 - 04/2004)
6. Distler, O: 7 articles (01/2021 - 10/2001)
7. Bernardi, Paolo: 7 articles (10/2014 - 04/2008)
8. Blaheta, Roman A: 7 articles (12/2012 - 04/2006)
9. Chiquet-Ehrismann, Ruth: 7 articles (09/2012 - 06/2003)
10. Zhuang, Shougang: 6 articles (01/2022 - 08/2010)

Related Diseases

1. Neoplasms (Cancer)
2. Fibrosis (Cirrhosis)
3. Proteinuria
4. Hypertrophy
5. Inflammation (Inflammations)

Related Drugs and Biologics

1. Fibronectins (Fibronectin)
2. Proteins (Proteins, Gene)
3. Messenger RNA (mRNA)
4. Periodic Acid
5. Collagen
6. Integrins
7. Tenascin
8. Transforming Growth Factor beta (TGF-beta)
9. Matrix Metalloproteinases (MMPs)
10. Intercellular Signaling Peptides and Proteins (Growth Factors)

Related Therapies and Procedures

1. Therapeutics
2. Radiotherapy
3. Ovariectomy (Oophorectomy)
4. Immunotherapy
5. Drug Therapy (Chemotherapy)