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Proto-Oncogene Proteins c-abl

Non-receptor tyrosine kinases encoded by the C-ABL GENES. They are distributed in both the cytoplasm and the nucleus. c-Abl plays a role in normal HEMATOPOIESIS especially of the myeloid lineage. Oncogenic transformation of c-abl arises when specific N-terminal amino acids are deleted, releasing the kinase from negative regulation.
Also Known As:
Proto-Oncogene Proteins abl; abl Proto-Oncogene Products; Products, abl Proto-Oncogene; Proteins abl, Proto-Oncogene; Proto Oncogene Proteins abl; Proto Oncogene Proteins c abl; Proto-Oncogene Products, abl; Proto-Oncogene Proteins, abl; abl Proto Oncogene Products; abl Proto Oncogene Proteins; abl, Proto-Oncogene Proteins; c abl Proteins; c-abl, Proto-Oncogene Proteins; abl Proto-Oncogene Proteins; c-abl Proteins
Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Niyazi, Maynur: 1 article (06/2003)
2. Araki, Tsutomu: 1 article (06/2003)
3. Sugisaki, Yuichi: 1 article (06/2003)
4. Kawanami, Oichi: 1 article (06/2003)
5. Konishi, Hideki: 1 article (06/2003)
6. Ghazizadeh, Mohammad: 1 article (06/2003)

Related Diseases

1. BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
2. Carcinoma (Carcinomatosis)