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Proto-Oncogene Proteins c-abl

Non-receptor tyrosine kinases encoded by the C-ABL GENES. They are distributed in both the cytoplasm and the nucleus. c-Abl plays a role in normal HEMATOPOIESIS especially of the myeloid lineage. Oncogenic transformation of c-abl arises when specific N-terminal amino acids are deleted, releasing the kinase from negative regulation.
Also Known As:
Proto-Oncogene Proteins abl; abl Proto-Oncogene Products; Products, abl Proto-Oncogene; Proteins abl, Proto-Oncogene; Proto Oncogene Proteins abl; Proto Oncogene Proteins c abl; Proto-Oncogene Products, abl; Proto-Oncogene Proteins, abl; abl Proto Oncogene Products; abl Proto Oncogene Proteins; abl, Proto-Oncogene Proteins; c abl Proteins; c-abl, Proto-Oncogene Proteins; abl Proto-Oncogene Proteins; c-abl Proteins
Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Abid, Fatma: 1 article (01/2020)
2. Belkhiri, Abbes: 1 article (01/2020)
3. El-Rifai, Wael: 1 article (01/2020)
4. Hong, Jun: 1 article (01/2020)
5. Peng, Dunfa: 1 article (01/2020)
6. Phillips, Sharon: 1 article (01/2020)
7. Revetta, Frank L: 1 article (01/2020)
8. Salaria, Safia N: 1 article (01/2020)
9. Washington, Mary K: 1 article (01/2020)
10. Araki, Tsutomu: 1 article (06/2003)

Related Diseases

1. Neoplasms (Cancer)
2. BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
3. Genetic Translocation (Chromosomal Translocation)
4. Carcinoma (Carcinomatosis)

Related Drugs and Biologics

1. Biomarkers (Surrogate Marker)
2. Proteins (Proteins, Gene)
3. Phosphotransferases (Kinase)