Leucine-2-Alanine Enkephalin (Enkephalin, Leucine 2 Alanine)

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86 relevant articles (6 outcomes, 11 trials/studies) found for this Bio-Agent

Description: A delta-selective opioid (ANALGESICS, OPIOID). It can cause transient depression of mean arterial blood pressure and heart rate.

Also Known As:

Enkephalin, Leucine 2 Alanine; Enkephalin, Leucine-2-Alanine; BW-180C; DADLE; Leu-Enkephalin-2-Ala; 2 Alanyl Leucine Enkephalin; 5 Leucine 2 Alanine Enkephalin; BW 180C; BW180C; Enkephalin, 2-Alanyl-Leucine; Enkephalin, 5-Leucine-2-Alanine; Enkephalin-2-Alanine, Leucine; Leu Enkephalin 2 Ala; Leucine Enkephalin 2 Alanine; 2-Alanyl-Leucine Enkephalin; 5-Leucine-2-Alanine Enkephalin; D-Ala(2)-D-Leu(5)-Enkephalin; Enkephalin-Leu,Ala(2); Leucine Enkephalin-2-Alanine; D-Leucine, N-(N-(N-(N-L-tyrosyl-D-alanyl)glycyl)-L-phenylalanyl)-

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins

Peptides: 16074

Opioid Peptides: 1052

Enkephalins: 853

Leucine Enkephalin: 268

Experts

1.	Han, Fei: 1 article (05/2008)
2.	Stezoski, S William: 1 article (05/2008)
3.	Drabek, Tomas: 1 article (05/2008)
4.	Kochanek, Patrick M: 1 article (05/2008)
5.	Tisherman, Samuel A: 1 article (05/2008)
6.	Stezoski, Jason: 1 article (05/2008)
7.	Garman, Robert H: 1 article (05/2008)
8.	Morhard, Ryan C: 1 article (05/2008)
9.	Furui, Junichiro: 1 article (09/2003)
10.	Yamanouchi, Kousyou: 1 article (09/2003)

Related Diseases

1.	Ischemia 08/16/2007 - "We found in our study that administration of DADLE 45 min before forebrain ischemia had significant protective effect against CA1 neuronal lose" 08/16/2007 - "This study was aimed to investigate whether intracerebroventricular (ICV) administration of DADLE has a neuroprotective effect against forebrain ischemia in rats" 09/01/2007 - "In contrast, 20 nM DADLE, although known to be protective before ischemia, failed to protect" 09/01/2007 - "We therefore tested whether DADLE at reperfusion could protect isolated rabbit hearts subjected to 30 min of regional ischemia and 120 min of reperfusion and whether this protection is dependent on Akt, ERK, and EGFR" 03/13/2007 - "Pre-ischemic treatment of DORs agonism with DADLE did not provide any neuroprotection to the hippocampus in rats subjected to forebrain ischemia." Get all the results and reference details, order at left...
2.	Seizures (Seizure) 08/01/1992 - "Systemic or intracisternal injection of both morphine and DADLE decreased the incidence of seizures and the seizure score in El mice in a dose-dependent manner" 08/12/1985 - "The results of this study demonstrated that the effects of DADLE to increase seizure threshold in the rat were primarily mediated by activation of a delta-opioid receptor system" 02/01/1987 - "Behaviorally, the DAGO and DADLE EEG seizures were nonconvulsive but were temporally associated with episodic bursts of wet-dog shakes" 02/01/1987 - "DAGO produced a greater number of seizure episodes with a greater overall incidence compared with DADLE, reflecting its potent effect to elicit EEG seizure activity in these rats" 02/01/1987 - "Only DAGO and DADLE were found to produce EEG seizures, with DAGO being 9 times more potent than DADLE" Get all the results and reference details, order at left...
3.	Reperfusion Injury 06/01/2002 - "Most notably, mesenteric ischemia/reperfusion injury was attenuated by DADLE: reperfusion contractile force was 47 +/- 5% versus 36 +/- 5% in DADLE-treated versus control segments (p < 0.01)" 05/01/2008 - "The delta opioid agonist DADLE ([D-Ala(2),D-Leu(5)]-enkephalin) was shown previously to be protective against ischemia-reperfusion injury in multiple organs, including brain" 09/01/2003 - "D-Ala2, D-Leu5] enkephalin (DADLE) protects liver against ischemia-reperfusion injury in the rat." Get all the results and reference details, order at left...
4.	Hemorrhagic Shock 06/