Alveolar Bone Loss

Subscribe to Selected New Research on Alveolar Bone Loss

300 relevant articles (21 outcomes, 62 trials/studies) found for this Disease

Description: The resorption of bone in the supporting structures of the MAXILLA or MANDIBLE.

Also Known As:

Alveolar Bone Losses; Alveolar Resorptions; Bone Losses, Alveolar; Bone Losses, Periodontal; Loss, Alveolar Bone; Loss, Periodontal Bone; Losses, Alveolar Bone; Losses, Periodontal Bone; Periodontal Bone Losses; Periodontal Resorptions; Resorption, Alveolar; Resorption, Periodontal; Resorptions, Alveolar; Resorptions, Periodontal; Alveolar Resorption; Bone Loss, Alveolar; Bone Loss, Periodontal; Periodontal Bone Loss; Periodontal Resorption

Relationship Network

Disease Context: Research Results

Musculoskeletal Diseases: 83

Bone Diseases: 2376

Bone Resorption: 8774

Alveolar Bone Loss: 300

Stomatognathic Diseases: 250

Mouth Diseases: 55

Periodontal Diseases: 3557

Alveolar Bone Loss: 300

Related Diseases

1.	Periodontitis
2.	Inflammation
3.	Periodontal Diseases (Periodontal Disease)
4.	Infection
5.	Hypokinesia (Bradykinesia)
48 Diseases and 129 more articles analyzed in the Full Patient-Physician Summary Report, order at left...

Experts

1.	Tatakis, Dimitris N: 3 articles (06/2004 - 06/2002)
2.	Garcia, Valdir Gouveia: 2 articles (06/2008 - 03/2007)
3.	de Almeida, Juliano Milanezi: 2 articles (06/2008 - 03/2007)
4.	Bosco, Alvaro Francisco: 2 articles (06/2008 - 03/2007)
5.	Nagata, Maria José Hitomi: 2 articles (06/2008 - 03/2007)
6.	Otremba, Jodie: 2 articles (10/2007 - 01/2007)
7.	Higgins, Linda S: 2 articles (10/2007 - 01/2007)
8.	Kirkwood, Keith L: 2 articles (10/2007 - 01/2007)
9.	Coatney, Derek D: 2 articles (10/2007 - 01/2007)
10.	Li, Fei: 2 articles (10/2007 - 01/2007)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Alveolar Bone Loss:

1.	Alendronate (Alendronate Sodium)FDA LinkGeneric 09/01/2003 - "CONCLUSIONS: The systemic administration of 0.5 mg/kg alendronate was effective in preventing alveolar bone loss and in modulating tissue factors" 10/01/2000 - "CONCLUSION: We conclude that ISA-13-like alendronate is effective in reducing alveolar bone loss when delivered at surgical sites" 08/01/2000 - "In the present study, we explored the effectiveness of different concentrations of alendronate, delivered at the surgical site at the time of surgery, in distant delivery in reducing alveolar bone loss" 10/01/2000 - "We have established that topical application of 20 mg/ml of alendronate placed at the surgical mucoperiosteal site produced a striking reduction of alveolar bone loss in the rat model" 08/01/2000 - "Alendronate given intravenously significantly reduced alveolar bone loss in mucoperiosteal flap procedures" Get all the results and reference details, order at left...
2.	Interleukin-10 (Interleukin 10)IBA 08/01/2003 - "Interleukin-10(-/-) mice had significantly greater alveolar bone loss than interleukin-10(+/+) mice (p = 0.006)" 12/01/2004 - "In the present study, we tested the hypothesis that endogenous interleukin-10 is a potent suppressor of Porphyromonas gingivalis-induced alveolar bone loss in vivo" 08/01/2003 - "The results of the present study suggest that lack of interleukin-10 leads to accelerated alveolar bone loss." 05/01/2008 - "Myeloid cell-specific Stat3-deficient mice exhibited increased periodontal bone loss (p < 0.001), whereas T cell- and B cell-specific Stat3 mice were resistant, suggesting that macrophages (MP) and/or polymorphonuclear leukocytes are the key target cells normally suppressed by IL-10" 12/01/2004 - "gingivalis-infected interleukin-10(-/-) mice exhibited severe alveolar bone loss compared to non-infected interleukin-10(-/-) and wild-type mice by day 42" Get all the results and reference details, order at left...
3.	DiphosphonatesIBA 07/01/1987 - "The effects of diphosphonates on alveolar bone loss." 06/01/2001 - "Future studies of the effect of bisphosphonates on the jaw BMC and alveolar bone loss, and analyses of the bone quality and jaw BMC/BMD in relation to implant treatment, without or with bone transplantation, are required." 07/01/2007 - "Efficacy of bisphosphonates for the control of alveolar bone loss in periodontitis." 07/01/2003 - "BACKGROUND: Recent animal studies have shown that a combination of chemically-modified tetracyclines together with bisphosphonates, when delivered systemically, are synergistically effective in suppressing periodontal bone loss" Get all the results and reference details, order at left...
4.	TetracyclinesIBA 07/01/2003 - "CONCLUSIONS: In the present study, we found that tetracyclines can be most effective in reducing alveolar bone loss when applied locally" 07/01/1994 - "The current study was undertaken to determine whether tetracyclines can inhibit alveolar bone loss in vivo due to a non-antimicrobial action of these drugs" 07/01/2002 - "Inhibition of matrix metalloproteinase-mediated periodontal bone loss in rats: a comparison of 6 chemically modified tetracyclines." 07/01/1994 - "Tetracyclines inhibit Porphyromonas gingivalis-induced alveolar bone loss in rats by a non-antimicrobial mechanism." 07/01/2003 - "BACKGROUND: Recent animal studies have shown that a combination of chemically-modified tetracyclines together with bisphosphonates, when delivered systemically, are synergistically effective in suppressing periodontal bone loss" Get all the results and reference details, order at left...
5.	Interleukin-1beta (Interleukin 1 beta)IBA 11/01/1995 - "Alveolar bone loss in active sites correlated with increased GCF levels of IL-1 beta and IL-2" 02/01/1998 - "Further studies are warranted to determine the full diagnostic potential of M-GCF levels of PGE2 and IL-1 beta for predicting risk of alveolar bone loss in patients with periodontitis and monitoring periodontal therapy effectiveness." 03/01/2007 - "A positive association was noted between alveolar bone loss and salivary concentrations of hepatocyte growth factor, and interleukin-1 beta, while a negative association was noted for alveolar bone loss and salivary osteonectin" 08/01/1997 - "The total amount of IL-1 alpha, IL-1 beta and the IL-1AI, but not total IL-1ra, were found to be correlated with alveolar bone loss score" 02/01/1998 - "Coordinate production of PGE2 and IL-1 beta in the gingival crevicular fluid of adults with periodontitis: its relationship to alveolar bone loss and disruption by twice daily treatment with ketorolac tromethamine oral rinse." Get all the results and reference details, order at left...
6.	Interferon Type II (Interferon, gamma)IBA 06/01/2005 - "In contrast to the inhibitory effect of gamma interferon (IFN-gamma) on RANKL-mediated osteoclastogenesis reported recently, alternative new evidence is demonstrated via studies of experimental periodontitis using humanized NOD/SCID and diabetic NOD mice and clinical human T-cell isolates from diseased periodontal tissues, where the presence of increasing IFN-gamma is clearly associated with (i) enhanced Actinobacillus actinomycetemcomitans-specific RANKL-expressing CD4(+) Th cell-mediated alveolar bone loss during the progression of periodontal disease and (ii) a concomitant and significantly increased coexpression of IFN-gamma in RANKL(+) CD4(+) Th cells" 08/01/2006 - "The results show significantly decreased RANKL+ Th1-associated alveolar bone loss and coexpression of human gamma interferon (hIFN-gamma) and human macrophage colony-stimulating factor, but not hIL-4, in RANKL+ Th cells compatible with those from successfully treated aggressive periodontitis subjects" 06/01/1999 - "CD4(+) T cells and the proinflammatory cytokines gamma interferon and interleukin-6 contribute to alveolar bone loss in mice." 04/01/2007 - "MATERIAL AND METHODS: Alveolar bone loss was measured histomorphometrically in interleukin-4, interleukin-10, interleukin-12p40, interferon-gamma (IFN-gamma) and tumor necrosis factor (TNF) knockout mice at 6, 16 and 30 wk of age" 02/01/2006 - "The expression of MMPs (MMP-1, 2 and 9) and RANKL was correlated with the expression of interleukin-1beta, tumor necrosis factor-alpha and interferon-gamma, in a time period characterized by the intense increase of inflammatory reaction and alveolar bone loss" Get all the results and reference details, order at left...
7.	DNA (Deoxyribonucleic Acid)IBA 07/01/2005 - "OBJECTIVE: To observe the protection against periodontal bone loss in the Sprague-Dawley (SD) rats periodontitis model, with the recombined plasmid pcDNA3.1+/kgpcd as DNA gene vaccine" 05/01/2007 - "The results of this study suggest that immunization with rgpA DNA vaccine via the nasal cavity is an effective method for preventing alveolar bone loss incurred by infection with P" 12/01/1990 - "Associations between six DNA probe-detected periodontal bacteria and alveolar bone loss and other clinical signs of periodontitis." Get all the results and reference details, order at left...
8.	2,6- dichloro- N- (3- methyl- 4- (3- methyl- 2- oxo- 1- imidazolidinyl)- 8- quinolinyl)benzamideIBA 07/01/2006 - "Oral administration of FR202126 significantly prevented alveolar bone loss in experimental periodontitis" 12/01/2005 - "Oral administration of FR202126 (u.i.d.) significantly prevented alveolar bone loss in experimental periodontitis which may offer a new approach to treatment of periodontal disease." 12/01/2005 - "This study examined the efficacy of a novel V-ATPase inhibitor, FR202126, in reducing alveolar bone loss caused by experimental periodontitis in rats" Get all the results and reference details, order at left...
9.	1- (5- Isoquinolinesulfonyl)- 2- Methylpiperazine (H 7)IBA 05/01/2006 - "RESULTS: EDTA, sodium orthovanadate, and H-7 were significantly effective in reducing alveolar bone loss" 05/01/2006 - "CONCLUSION: EDTA, sodium orthovanadate, and H-7 are effective in reducing alveolar bone loss in rats following mucoperiosteum surgery." 05/01/2006 - "In this study, four drugs were selected, including cytochalasin D, EDTA, sodium orthovanadate, and H-7, all influencing the cytoskeleton-integrin-extracellular matrix (ECM) pathway, for their ability to reduce alveolar bone loss by local application" Get all the results and reference details, order at left...
10.	Vanadates (Orthovanadate)IBA 05/01/2006 - "RESULTS: EDTA, sodium orthovanadate, and H-7 were significantly effective in reducing alveolar bone loss" 05/01/2006 - "CONCLUSION: EDTA, sodium orthovanadate, and H-7 are effective in reducing alveolar bone loss in rats following mucoperiosteum surgery." 05/01/2006 - "In this study, four drugs were selected, including cytochalasin D, EDTA, sodium orthovanadate, and H-7, all influencing the cytoskeleton-integrin-extracellular matrix (ECM) pathway, for their ability to reduce alveolar bone loss by local application" Get all the results and reference details, order at left...
194 Drugs and Important Bio-Agents and 221 more articles analyzed in the Full Patient-Physician Summary Report, order at left...

Therapies and Procedures

1.	Ligation 11/15/2006 - "In vivo studies revealed that ligature-induced periodontal bone loss is significantly greater in Akita mice compared with WT. Moreover, intravital microscopy of gingival vessels showed that leukocyte rolling and attachment to the vascular endothelium is enhanced in periodontal vessels of Akita mice" 06/01/2008 - "OBJECTIVE: The aim of this study was to compare ligature-induced alveolar bone loss between obese and non-obese rats" 06/01/2008 - "Test animals demonstrated a mean (SD) alveolar bone loss of 0.51 (0.11) mm and in the controls 0.52 (0.14) mm in teeth with ligatures" 11/01/2007 - "RESULTS: Intra-group comparisons showed significantly higher alveolar bone loss mean values in maxillary sides with ligature (paired sample t-test; p<0.05)" 04/01/2005 - "CONCLUSION: Soluble beta-1,3/1,6-glucan administered by the oral route diminishes ligature-induced periodontal bone loss in this model" Get all the results and reference details, order at left...
2.	Complete Denture (Dentures, Complete) 09/01/2003 - "The aim of this study was to establish if smoking affects alveolar bone loss in complete denture wearers" 03/01/1994 - "A 4-year cephalometric study was conducted on 14 wearers of complete dentures to quantify the anterior alveolar bone loss and to study any associated changes in the maxillomandibular relationships" 08/01/1992 - "Due to extreme alveolar resorption many edentulous patients wearing complete dentures suffer from loss of function of the orofacial system" 01/01/1983 - "Complete denture for cases with marked alveolar resorption]" 01/01/1983 - "Complete denture in cases with marked alveolar resorption--an approach based on C" Get all the results and reference details, order at left...
3.	Ovariectomy (Oophorectomy) 09/01/1997 - "Alveolar bone loss one year following ovariectomy in sheep." 04/01/2002 - "These compounds may also be effective in preventing bone loss associated with hypodynamia or immobility, ovariectomy or postmenopausal hypoestrogenia, chronic corticosteroid use, renal osteodystrophy, hyperparathyroidism and other metabolic disorders affecting the calcified tissues, including alveolar bone loss in periodontal disease as well as dental hard tissues destruction." Get all the results and reference details, order at left...
4.	Aftercare (After-Treatment) 12/01/2000 - "gingivalis in plaque after treatment might be indicative of progressive alveolar bone loss." 12/01/2000 - "Progressive alveolar bone loss was determined using digital subtraction radiography with standardized radiographs taken at baseline and 6 months after treatment" 09/01/2002 - "mean HGF content in GCF from sites with clinically healthy gingiva, defined by the absence of overt signs of gingival inflammation and a probing depth (PD) <3 mm, was 1.7 ng/ml, and that of periodontitis, defined by obvious alveolar bone loss detected by radiographic examination and a PD> or =3 mm, was 3.23 ng/ml. Although treating the periodontitis did not significantly decrease the HGF concentration despite significantly improved clinical scores such as PD and Gingival Index, the total amount of HGF in GCF did decrease significantly after treatment" Get all the results and reference details, order at left...
5.	Tooth Extraction (Tooth Extractions) 07/01/2005 - "This study suggests that tooth hard tissue's electrochemical characteristic might affect the remodeling of alveolar bone, and tooth supraeruption and the alveolar bone loss after tooth extraction might result from the redundant or lack of root electrochemical stimulation to bone." 04/01/2008 - "The concomitant placement of particulate material and a membrane at the time of tooth extraction offers the advantage of minimizing if not eliminating significant 3-dimensional alveolar resorption" 01/01/2003 - "Alveolar bone loss (RRR) is a continuous process following tooth extraction, more pronounced during the first few months after the tooth extraction than later" 09/01/2004 - "To investigate other factors, postoperative bleeding, age, gender, PT-INR level, combined use of anti-platelet drugs, conditions of extracted tooth, a number of tooth extractions at a treatment, methods of management for warfarin therapy, degree of the alveolar bone loss and size of radiolucency of apical region were examined in this study" Get all the results and reference details, order at left...
42 Therapies and Procedures and 97 more articles analyzed in the Full Patient-Physician Summary Report, order at left...

Patient-Physician
Research Summary Report
on Alveolar Bone Loss

*WARNING* This specific disease subtype has a relatively small number of significant evidence outcomes. You may proceed to order anyway, or go back to the search field and enter a more general type of the target illness. Once your report has been ordered, however, we can't refund the purchase.

CureHunter Patient-Physician Summary Reports collect in one document all the medications ever reported in the US National Library of Medicine—1949 to the present—to be effective against your target disease. CureHunter research summary reports will vary in length from 25 to 250 pages. Analytic charts allow you and your physicians to see at a glance your medication options—including new, promising, off-label and experimental.

Free Updates for 1 Year
All 21 Outcomes
Top 194 Key Medications
Top 42 Key Therapies and Procedures
Detailed History Charts
Full Research Reference Details
Sample PDF for "Psoriasis" >>

Price:

$24.00 & Delivery via PDF download,
updates for 1 year

Research Interface

Rapidly retrieve summaries of all the evidence for any disease in seconds. Save hours of search and analysis time. CureHunter is unlike any "search engine" you have ever used. Where standard "search engines" produce lists of links, CureHunter quantifies evidence, extracts it from the literature and calculates a result you can use to immediately facilitate evidence based decision making in Real Clinical Time.

Unlimited Disease, Drug and Therapy Search
2 clicks from Disease to Drug to Evidence
Trial References
All the Positive Outcomes
Detailed Relationship Timeline Charts
Full Article Reference Details
Includes Mobile Interface Subscription
One-click to FDA Products/Patents
Request Institution License details >>

Price:

$490.00 access via web interface, 1 year subscription

Proceed to Checkout >>

Mobile Interface

Retrieve summaries of all the evidence for any disease from your Mobile Phone or PDA. Accelerate decision making in the field. Speed up your study of new drug and disease domains. Refresh your knowledge on the road.

Access from any web enabled PDA or Phone
Trial references
All the Positive Outcomes
Drug and Therapy searches
Full Article Reference Details
Try Mobile Interface >>

Price:

$45.00 access via "curehunter.com/m", 1 year subscription

Proceed to Checkout >>