|1.||Breit, Rainer: 2 articles (02/2006 - 05/2002)|
|2.||Hartmann, Frank: 2 articles (02/2006 - 05/2002)|
|3.||Kubuschok, Boris: 2 articles (02/2006 - 05/2002)|
|4.||Schilling, Martin: 2 articles (02/2006 - 05/2002)|
|5.||Pfreundschuh, Michael: 2 articles (02/2006 - 05/2002)|
|6.||Russo, Eleonora: 1 article (12/2014)|
|7.||Bifulco, Maurizio: 1 article (12/2014)|
|8.||Vitale, Mario: 1 article (12/2014)|
|9.||Salzano, Marcella: 1 article (12/2014)|
|10.||Salzano, Salvatore: 1 article (12/2014)|
05/01/1993 - "We also identified ras p21 products in these neoplasms by means of p21 ras monoclonal antibody studies. "
10/01/1989 - "We also identified ras p21 products in these neoplasms by means of p21 ras monoclonal antibody studies. "
12/01/2014 - "Activating mutations in RAS genes and p21 Ras overactivation are common occurrences in a variety of human tumors. "
06/01/2013 - "p21 ras acts as an initiator in HCC complicating type 4 chronic HCV and is downregulated with HCC progression, which most likely promotes tumor cell survival because it facilitates the downregulation of apoptosis with tumor progression."
05/04/2007 - "Selective suppression of PKCdelta activity and consequent induction of apoptosis is a potential strategy for targeting of tumor cells containing an activated p21(RAS)."
|2.||Lung Neoplasms (Lung Cancer)
01/01/2003 - "Therefore, our study suggests that P21 ras and P53 protein play a role in the pathogenesis of NSCLCs but they have no value as a prognostic markers in the case of lung cancers."
01/01/2000 - "The presence of a ras mutation or p21(ras) oncoprotein overexpression correlates with an unfavorable prognosis for patients with nonsmall-cell lung cancer (3). "
09/01/1993 - "The present study indicated that there was P21(ras) in human lung cancer and normal control and the expression level of ras gene in lung cancer was related to the differentiation of cancer."
09/01/1993 - "[A study on P21(ras) in human lung cancer and body fluid of cancer patients]."
01/01/2003 - "Human non-small-cell lung cancers (NSCLCs) of 48 patients were analyzed immunohistochemically to detect P21 ras and P53 proteins expression. "
|3.||Colonic Neoplasms (Colon Cancer)
10/01/1995 - "The current study examined sera from 160 colon cancer patients and 60 normal individuals to determine whether antibody to mutated p21 ras protein was present. "
07/15/1995 - "The current study examined whether primed T cell immunity to mutant p21 ras proteins and/or peptides can be detected in patients with pancreatic or colon cancer. "
|4.||Hepatocellular Carcinoma (Hepatoma)
06/01/2013 - "The goal of this study was to investigate the status of p21 ras in early-stage/low-grade and late-stage/high-grade hepatocellular carcinoma and its possible link to apoptosis. "
02/01/2000 - "This demonstrates that the activated p21(Ras) protein has anti-apoptotic activity in transformed mouse hepatocytes in vivo and suggests that the preferential outgrowth of Ha-ras-mutated hepatoma cells is mediated by suppression of apoptosis rather than by stimulation of cell division."
08/01/1996 - "However, the correlation between hepatocellular carcinoma and ALDH-3 expression was better than p21 Ras or the other markers we have studied. "
08/01/1996 - "For all treatment groups, both the early (26 weeks) expression of p21 Ras and ALDH-3 correlated with hepatocellular carcinoma incidence at 52 weeks. "
06/01/2013 - "Although p21 ras has been reported to be upregulated in hepatocellular carcinoma complicating chronic hepatitis C type I, p21 ras has a different role in advanced stages, as it has been found to be downregulated. "
|5.||Neoplasm Metastasis (Metastasis)
01/01/1989 - "While these expression and mutation studies support the idea that p21 ras directly regulates metastasis formation, it is also evident that there are many examples of human and murine cancers which show no differences in ras expression in primary and metastatic tumor cells. "
01/01/2003 - "No significant association of P21 ras and P53 expression was found with age, histologic type, histologic grade, tumor size or lymph node metastasis of the studied NSCLCs. "
03/15/1986 - "The metastases expressed the EJ c-Ha-ras-1 p21 ras proteins; however, one metastasis was discovered that had lost the expression of the c-Ha-ras-1 gene. "
|1.||Proteins (Proteins, Gene)
|4.||Epidermal Growth Factor Receptor (EGF Receptor)
|5.||DNA (Deoxyribonucleic Acid)
|8.||rho GTP-Binding Proteins (rho GTP-Binding Protein)
|10.||Proto-Oncogene Proteins c-jun