Oncogene Protein gp140(v-fms)
Transforming glycoprotein coded by the fms oncogene from the Susan McDonough strain of feline sarcoma virus (SM-FeSV). The oncogene protein v-fms lacks sequences, which, in the highly homologous proto-oncogene protein c-fms (CSF-1 receptor), normally serve to regulate its tyrosine kinase activity. The missing sequences in v-fms mimic the effect of ligand and lead to constitutive cell growth. The protein gp120(v-fms) is post-translationally modified to generate gp140(v-fms).
Also Known As:
fms Oncogene Product gp120; fms Oncogene Product gp140; gp120 v-fms; gp140 v-fms; gp120 v fms; gp140 v fms; v fms Protein; v-fms, gp120; v-fms, gp140; fms Oncogene Protein gp120; fms Oncogene Protein gp140; gp120(v-fms); gp140(v-fms); v-fms Protein
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