Dietary Phosphorus

Phosphorus used in foods or obtained from food. This element is a major intracellular component which plays an important role in many biochemical pathways relating to normal physiological functions. High concentrations of dietary phosphorus can cause nephrocalcinosis which is associated with impaired kidney function. Low concentrations of dietary phosphorus cause an increase in calcitriol in the blood and osteoporosis.

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Networked: 230 relevant articles (5 outcomes, 22 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Kalantar-Zadeh, Kamyar: 8 articles (01/2017 - 03/2010)
2.	Taketani, Yutaka: 7 articles (11/2020 - 01/2007)
3.	Takeda, Eiji: 6 articles (11/2020 - 01/2007)
4.	Uribarri, Jaime: 5 articles (12/2021 - 07/2007)
5.	Kovesdy, Csaba P: 5 articles (05/2015 - 03/2010)
6.	Gutiérrez, Orlando M: 5 articles (11/2013 - 07/2010)
7.	Yamamoto, Hironori: 4 articles (11/2020 - 01/2007)
8.	Sevick, Mary Ann: 4 articles (05/2017 - 02/2008)
9.	Arai, Hidekazu: 4 articles (03/2017 - 07/2014)
10.	Morimoto, Yuuka: 4 articles (03/2017 - 07/2014)

Related Diseases

1.	Hyperphosphatemia 11/01/2023 - "This review aims to discuss the evolution of dietary phosphorus management while highlighting areas for future research that can help move the field toward stronger evidence-based guidance to prevent and treat hyperphosphatemia." 03/01/2017 - "Accurate assessment of dietary phosphorus intake is necessary to prevent hyperphosphatemia. " 01/01/2014 - "These findings suggest that long-term dietary phosphorus loads and long-term hyperphosphatemia may have important negative effects on bone health. " 11/01/2007 - "This new management concept for hyperphosphatemia is the first to establish a direct link between dietary phosphorus intake and PB dose and to empower patients to self-adjust PB dose according to dietary phosphorus intake. " 08/01/2015 - "The present study was conducted to analyze the dietary phosphorus intake and distribution in different food categories in peritoneal dialysis (PD) patients, to evaluate the relationship between dietary phosphorus intake and hyperphosphatemia. "
2.	Malnutrition (Nutritional Deficiencies) 07/26/2022 - "(2) Methods: Among 415 patients from the multi-center prospective Malnutrition, Diet, and Racial Disparities in Kidney Disease Study, we examined the associations of absolute dietary phosphorus intake (mg/day), ascertained by food frequency questionnaires, with all-cause mortality using multivariable Cox models. " 11/22/2023 - "The Hidden and Complex Relationship between Dietary Phosphorus and Malnutrition in Hemodialysis Patients with Chronic Kidney Disease." 07/01/2009 - "Better reporting of phosphorus content of foods by manufacturers could result in improved dietary phosphorus control without risk of protein malnutrition." 01/01/2006 - "This can represent additional advice to the patient for limiting the dietary phosphorus load at the same protein intake, leading to a better control of phosphate balance together with a lower risk of protein malnutrition." 01/01/2016 - "Introduction Osteodystrophy management includes dietary phosphorus restriction, which may limit protein intake, exacerbate malnutrition-inflammation syndrome and mortality among hemodialysis patients. "
3.	Urolithiasis 09/01/1987 - "It is concluded that supplemental dietary phosphorus is most effective for protection against silica urolithiasis under conditions contributing toward urinary acidification due to a possible synergism between dietary phosphorus and urinary acidifying salts."
4.	Disease Progression 11/01/2014 - "Dietary phosphorus overloading promoted dystrophic disease progression in mdx mice, whereas restricting dietary phosphorus intake improved muscle pathological characteristics and function. " 11/01/2014 - "In contrast, minimal muscle necrosis and inflammation were observed in exercised mdx mice fed a low-phosphorus diet, suggesting potential beneficial therapeutic effects of lowering dietary phosphorus intake on disease progression. "
5.	Kidney Calculi (Kidney Stone) 12/01/1984 - "The protective effects of dietary magnesium were counteracted when dietary phosphorus levels were increased from 400 mg to 550 or 700 mg. If the dietary content of phosphorus and magnesium permitted the formation of renal calculi, the severity of the condition was also influenced by the dietary level of calcium. "

Related Drugs and Biologics

1.	Phosphorus (Red Phosphorus)
2.	Calcium
3.	Proteins (Proteins, Gene)
4.	Salts
5.	Phosphates (Orthophosphate)
6.	Magnesium
7.	Silicon Dioxide (Silica)
8.	Calcitriol (Calcijex)
9.	Parathyroid Hormone (Parathormone)
10.	Potassium

Related Therapies and Procedures

1.	Renal Dialysis (Hemodialysis)
2.	Peritoneal Dialysis
3.	Protein-Restricted Diet (Diet, Protein Restricted)
4.	Therapeutics
5.	Conservative Treatment