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N-Methyl-D-Aspartate Receptors (NMDA Receptors)

A class of ionotropic glutamate receptors characterized by affinity for N-methyl-D-aspartate. NMDA receptors have an allosteric binding site for glycine which must be occupied for the channel to open efficiently and a site within the channel itself to which magnesium ions bind in a voltage-dependent manner. The positive voltage dependence of channel conductance and the high permeability of the conducting channel to calcium ions (as well as to monovalent cations) are important in excitotoxicity and neuronal plasticity.
Also Known As:
NMDA Receptors; Receptors, N-Methyl-D-Aspartate; N-Methylaspartate Receptors; Receptors, N-Methylaspartate; N Methyl D Aspartate Receptors; N Methylaspartate Receptors; NMDA Receptor Ionophore Complex; Receptors, N Methyl D Aspartate; Receptors, N Methylaspartate; NMDA Receptor-Ionophore Complex; Receptors, NMDA
Networked: 2157 relevant articles (56 outcomes, 188 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Felipo, Vicente: 12 articles (12/2015 - 08/2002)
2. Gmiro, V E: 11 articles (05/2014 - 03/2000)
3. Hashimoto, Kenji: 9 articles (09/2014 - 06/2005)
4. Magazanik, L G: 8 articles (12/2012 - 09/2002)
5. Vécsei, László: 7 articles (11/2014 - 04/2004)
6. Cauli, Omar: 7 articles (06/2014 - 11/2007)
7. Biegon, Anat: 7 articles (01/2014 - 06/2003)
8. Coyle, Joseph T: 7 articles (09/2012 - 01/2002)
9. Javitt, Daniel C: 7 articles (01/2010 - 01/2004)
10. Llansola, Marta: 6 articles (12/2015 - 08/2002)

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2. Pain (Aches)
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Related Drugs and Biologics

1. N-Methylaspartate (NMDA)
2. Glutamic Acid (Glutamate)
3. Dizocilpine Maleate (Dizocilpine)
4. Ketamine
5. Calcium
6. Memantine (Namenda)
7. Magnesium
8. Levodopa (L Dopa)
9. Ammonia
10. AMPA Receptors (AMPA Receptor)

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