|1.||Felipo, Vicente: 12 articles (12/2015 - 08/2002)|
|2.||Gmiro, V E: 11 articles (05/2014 - 03/2000)|
|3.||Hashimoto, Kenji: 9 articles (09/2014 - 06/2005)|
|4.||Magazanik, L G: 8 articles (12/2012 - 09/2002)|
|5.||Vécsei, László: 7 articles (11/2014 - 04/2004)|
|6.||Cauli, Omar: 7 articles (06/2014 - 11/2007)|
|7.||Biegon, Anat: 7 articles (01/2014 - 06/2003)|
|8.||Coyle, Joseph T: 7 articles (09/2012 - 01/2002)|
|9.||Javitt, Daniel C: 7 articles (01/2010 - 01/2004)|
|10.||Llansola, Marta: 6 articles (12/2015 - 08/2002)|
10/09/1999 - "These findings suggest that pregnancy affords some protection against seizures induced by an activation of NMDA receptors in the brain."
12/01/2012 - "The results of the present study suggest that NMDA receptors are involved in the molecular mechanisms of seizures of different etiologies."
06/08/2007 - "While in this study we present novel data about the role of the GABAergic system in MMA-induced convulsions, the central role of NMDA receptors in the neurochemical actions of MMA is further reinforced since they seem to trigger GABAergic failure."
03/01/2004 - "The results from these studies suggest that NMDA receptors containing the NR2B subunit may contribute to the expression of fully kindled secondarily generalized seizures; however, they appear less important for the development of kindling. "
10/01/1989 - "These studies were conducted to determine whether amygdaloid kindling results in the long-term alteration of NMDA receptors which could explain the persistent reduction in seizure threshold seen in this phenomenon. "
02/01/2000 - "Our results suggest that intrathecal administration of MgSO(4) may be therapeutically beneficial for patients with tonic pain involving the spinal NMDA receptors."
04/01/2010 - "The current study shows that NMDA receptors in supraspinal facilitatory sites maintain noninflammatory muscle pain. "
01/01/2010 - "Our study thus introduces a new concept of more than two drugs acting on opioid and NMDA receptors to modulate pain response."
09/25/2007 - "In this study, we used cortex-specific NR1 knockout mice (C57BL/6 strain) to elucidate the role of cortical NMDA receptors in pain processes. "
06/01/2004 - "Previous studies have indicated an involvement of NMDA receptors in the development of beta-opioid tolerance and associated abnormal pain sensitivity. "
|3.||Schizophrenia (Dementia Praecox)
01/01/2014 - "Our study was based on the hypothesis that a non competitive antagonist of NMDA receptors can improve clinical effects of antipsychotic therapy in a subgroup of patients with schizophrenia with clinical signs of glutamatergic hyperfunction such as catatonic symptoms and disorganization. "
01/01/2012 - "Postmortem studies have revealed abnormalities in endogenous modulators of NMDA receptors in schizophrenia as well as components of a postsynaptic density where NMDA receptors are localized. "
01/01/2011 - "These data show a significant downregulation of NMDA receptors due to dysbindin deficiency and illuminate molecular mechanisms mediating the association between dysbindin insufficiency and cognitive impairments associated with schizophrenia, encouraging study of the dysbindin/NR1 expression association in humans with schizophrenia."
10/01/2006 - "Since hypofunction of NMDA receptors has been implicated in the pathophysiology of schizophrenia, this study tests the hypothesis that GlyT1 genetic variants confer susceptibility to schizophrenia. "
04/15/2006 - "Evidence from previous studies indicate that NMDA receptors contribute to the pathophysiology of schizophrenia. "
03/01/2015 - "To enhance understanding of the underlying mechanisms, the current study examined the role of NMDA receptors in mediating the beneficial effects of Post C (3 min ischemia) administered 2 days after GCI in adult male rats. "
06/01/2008 - "This study explored the role of NMDA receptors in ischemia-reperfusion-induced renal dysfunction in rats. "
09/01/1996 - "These findings contrast with results from parallel studies showing increased striatal binding to NMDA receptors following ischemia. "
10/01/2013 - "Our results demonstrate that enhanced Ca(2+) activity of the astrocytic network plays a key role on the activation of extrasynaptic NMDA receptors in hippocampal neurons, which enhances brain damage during ischemia. "
10/01/2013 - "Although growing evidence suggests that activation of extrasynaptic NMDA receptors initiates neuronal death, no direct evidence demonstrated their activation during ischemia. "
|5.||Neuralgia (Stump Neuralgia)
11/01/2010 - "Thus, neuropathic pain symptoms can be attenuated by targeting the Mg-mediated blockade of NMDA receptors, offering new therapeutic opportunities for the management of chronic neuropathic pain."
02/01/2006 - "Anatomical, biochemical and pharmacological studies over the past five years have greatly added to our understanding of the role of NR2B subunit-containing NMDA receptors in chronic and neuropathic pain states, and have shown that NR2B-mediated analgesic effects might be supra- rather than intra-spinally mediated, and that phosphorylation of the NR2B subunit could be responsible for the initiation and maintenance of the central sensitization seen in neuropathic pain states. "
09/01/2002 - "Because recent studies emphasized the role of peripherally distributed NMDA receptors in processing the nociceptive information, we investigated whether peripheral application of the ointment containing KET is able to attenuate the symptoms of local neuropathic pain. "
05/14/2013 - "We found that in a mouse model in which peripheral nerve injury leads to the development of neuropathic pain, the insular cortex showed changes in synaptic plasticity, which were associated with a long-term increase in the amount of synaptic N-methyl-d-aspartate receptors (NMDARs), but not that of extrasynaptic NMDARs. "
05/14/2013 - "An increase in synaptic NMDA receptors in the insular cortex contributes to neuropathic pain."
|2.||Glutamic Acid (Glutamate)
|3.||Dizocilpine Maleate (Dizocilpine)
|8.||Levodopa (L Dopa)
|10.||AMPA Receptors (AMPA Receptor)