|1.||Welte, Karl: 6 articles (05/2010 - 04/2002)|
|2.||Touw, Ivo P: 4 articles (06/2010 - 08/2004)|
|3.||Zeidler, Cornelia: 4 articles (07/2008 - 04/2002)|
|4.||Germeshausen, Manuela: 3 articles (05/2010 - 01/2007)|
|5.||Schneider, Armin: 3 articles (01/2010 - 05/2006)|
|6.||Schäbitz, Wolf-Rüdiger: 3 articles (04/2007 - 05/2006)|
|7.||Touw, I P: 3 articles (12/2006 - 04/2001)|
|8.||Alter, Blanche P: 3 articles (07/2006 - 04/2002)|
|9.||Dale, David C: 3 articles (07/2006 - 05/2006)|
|10.||Freedman, Melvin H: 3 articles (07/2006 - 04/2002)|
07/01/2013 - "G-CSF receptor positive (aka G-CSFr(+) or CD114(+)) cells isolated from a primary tumor and the NGP cell line by flow cytometry were highly tumorigenic and capable of both self-renewal and differentiation to progeny cells. "
07/01/2009 - "LCSCs shared with the primary tumors the expression of various OC-associated markers, including cMet and G-CSF receptor. "
10/01/2007 - "G-CSF receptor was not detected to be expressed in the advanced-stage tumor. "
04/01/2001 - "Despite the presence of the G-CSF receptor in all biopsies and cell lines, no proliferation was found after rhG-CSF incubation of the cell lines or the tumor samples for 3 and for 6 days, respectively. "
04/01/2001 - "Granulocyte colony-stimulating factor receptors (G-CSFR) have been observed on the surface of not only hematopoietic cells but also several cancer cells. "
|2.||Acquired Immunodeficiency Syndrome (AIDS)
|3.||Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
03/01/2006 - "Because patients with a truncated G-CSF receptor have a high risk of developing acute myeloid leukemia (AML), we hypothesized that dysregulation of ROSs contributes to leukemogenesis. "
01/15/2005 - "In the subset of patients with SCN transforming to acute myeloid leukemia (AML), mutations that truncate the cytoplasmic tail of the G-CSF receptor (G-CSFR) have been detected. "
05/01/2003 - "The detection of flow cytometric G-CSF receptor expression and it's effect on therapy in acute myeloid leukemia."
12/01/2001 - "SCN patients with mutations in the G-CSF receptor gene are predisposed to acute myeloid leukemia. "
08/15/1997 - "These findings suggest the possibility that the soluble G-CSF receptor could be used in a clinical application for acute myeloblastic leukemia patients in the future."
01/01/1996 - "The results of our present study demonstrate that rhG-CSF reduced the growth of L-8801 leukemic cells in vitro and in vivo mediated through G-CSF receptors, thereby suppressing the development of leukemia."
07/01/2005 - "Because SCN patients with a mutation in the G-CSF receptor frequently develop leukemia, this 3-base pair deletion in the juxtamembrane sequence of the G-CSF receptor gene in this patient may be one step in the course of leukemic transformation."
04/01/1997 - "G-CSF receptor anomaly -the intra-cellular carboxy terminal region- was noted in a few patients (6 out of 54), initially in two patients who later developed secondary leukemia. "
04/01/1993 - "With this simplified method, G-CSF receptors were detected on almost all of the myeloid acute leukemia cells, but not on the nonmyeloid leukemic cells. "
06/01/1992 - "Granulocyte colony-stimulating factor receptors on human acute leukemia: biphenotypic leukemic cells possess granulocyte colony-stimulating factor receptors."
07/01/2008 - "G-CSF receptor mutations in patients with congenital neutropenia."
04/01/1997 - "No point mutations in the G-CSF receptor critical domain could be detected in cells from the other 24 congenital neutropenia patients. "
04/01/1997 - "Among these four congenital neutropenia patients with a mutated G-CSF receptor, two developed AML. "
04/01/1997 - "Four of 28 patients with congenital neutropenia displayed a point mutation in the tested cytoplasmic region of the G-CSF receptor gene. "
01/01/1997 - "Similar results were obtained by Touw et al., demonstrating that five out of 25 patients with congenital neutropenia reveal G-CSF receptor mutations. "
|1.||Granulocyte Colony-Stimulating Factor (G-CSF)
|2.||Messenger RNA (mRNA)
|3.||Severe congenital neutropenia
|4.||Recombinant Granulocyte Colony Stimulating Factor (Recombinant G CSF)
|5.||Leukocyte Elastase (Neutrophil Elastase)
|6.||severe chronic Neutropenia
|7.||Nonsense Codon (Nonsense Mutation)
|8.||Surface Antigens (Surface Antigen)
|10.||Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)
|1.||Drug Therapy (Chemotherapy)
|3.||Transplantation (Transplant Recipients)