Retinoblastoma Genes
Tumor suppressor genes located on human chromosome 13 in the region 13q14 and coding for a family of phosphoproteins with molecular weights ranging from 104 kDa to 115 kDa. One copy of the wild-type Rb gene is necessary for normal retinal development. Loss or inactivation of both alleles at this locus results in retinoblastoma.
Also Known As:
Genes, Retinoblastoma; Gene, Rb; Gene, Retinoblastoma; Rb Gene; Retinoblastoma Gene; Genes, Rb; Rb Genes
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