|1.||Lees, Jacqueline A: 8 articles (05/2013 - 04/2002)|
|2.||Hinds, Philip W: 6 articles (05/2010 - 03/2003)|
|3.||Sakai, Toshiyuki: 5 articles (01/2015 - 05/2007)|
|4.||Bronson, Roderick T: 5 articles (08/2011 - 04/2002)|
|5.||Slack, Ruth S: 5 articles (07/2007 - 02/2002)|
|6.||Mignotte, Bernard: 4 articles (09/2015 - 05/2005)|
|7.||Blanck, George: 4 articles (12/2014 - 02/2006)|
|8.||Zhang, Peng: 4 articles (09/2014 - 01/2012)|
|9.||Dong, Shang-Wen: 4 articles (09/2014 - 01/2012)|
|10.||Wang, Yuan-Guo: 4 articles (09/2014 - 01/2012)|
|1.||Retinoblastoma (Glioblastoma, Retinal)
09/01/2004 - "To develop and use improved Semliki Forest vectors (SFVs) for functional and structural analyses of the retinoblastoma protein (RB) in developing retina and retinoblastoma cells. "
09/01/2004 - "Retinoblastoma protein purification and transduction of retina and retinoblastoma cells using improved alphavirus vectors."
03/05/2004 - "Previous studies have suggested that tTG may modulate retinoblastoma (Rb) protein, an important suppressor of apoptosis. "
01/01/1998 - "Two of the cell lines that express the retinoblastoma (Rb) protein had no sign of a deregulated Rb pathway but further studies at the protein level are necessary to demonstrate whether these two cell lines should have a normal Rb pathway or whether they will join the majority of cell lines with deregulated Rb pathway."
03/27/1995 - "Studies of the retinoblastoma (RB) gene product suggest that it may work as a fundamental regulator to coordinate pathways of cellular growth and differentiation. "
09/01/2014 - "Our previous studies indicate that the NRP/B-BTB/POZ domain is involved in the dimerization of NRP/B and in a complex formation with the tumor suppressor, retinoblastoma protein. "
01/01/2014 - "LAP2α has been reported to regulate cell proliferation by affecting the activity of retinoblastoma protein in tissue progenitor cells and numerous studies showed upregulation of LAP2α in cancer. "
04/01/2013 - "The aim of this study was to determine whether there are differences in the expression and localization of RB protein in HER2-positive breast cancers compared to breast cancers showing no expression of HER2. "
01/01/2012 - "Previous studies showed that the SV40Tag oncoprotein binds to and inactivates tumor suppressors p53 and retinoblastoma protein (Rb), thereby inducing tumorigenesis. "
08/16/2011 - "Previous studies suggested that inhibition of RBP2 contributed to tumor suppression by the retinoblastoma protein (pRB). "
|3.||Breast Neoplasms (Breast Cancer)
04/01/2013 - "There are only a few published studies on the expression and localization of RB protein in the cells of HER2-positive breast cancer. "
08/17/2000 - "In this study we analysed the growth suppressive effect of HPR on human breast cancer cell lines in vitro and the role of the retinoblastoma protein (pRb) in this response. "
04/01/1994 - "Expression of retinoblastoma protein in human breast cancer: an immunohistochemical study."
04/01/2013 - "Active transport of RB protein from the nucleus to the cytoplasm as one of the development mechanisms of HER2-positive breast cancer."
05/01/2012 - "Retinoblastoma protein determines aggressiveness in triple-negative breast cancer."
|4.||Urinary Bladder Neoplasms (Bladder Cancer)
05/01/2010 - "Identification of molecular prognosticators that might be helpful in discriminating between responders and nonresponders to BCG treatment is therefore of major clinical importance; thus we focused on the cell-cycle related retinoblastoma protein (pRB), which had been already investigated in bladder cancer. "
07/21/2003 - "The objective of the study was to investigate the predictive value of various clinical, biochemical, and histopathological parameters, with special emphasis on the expression of the retinoblastoma protein (pRB), on the radiation response in bladder cancer. "
02/04/1999 - "Recent studies have shown that patients whose bladder cancer exhibit overexpression of RB protein as measured by immunohistochemical analysis do equally poorly as those with loss of RB function. "
08/19/1992 - "This study demonstrates that altered patterns of Rb protein expression may be an important prognostic variable in patients presenting with invasive bladder cancer."
01/01/2015 - "There are many patients with bladder cancer with confirmed absence of retinoblastoma protein, which is responsible of holding on the process of coming up the cells with mutation into synthesis, where the replication process undergoes. "
|5.||Osteosarcoma (Osteogenic Sarcoma)
10/01/1997 - "We tested the efficacy of our system by expressing the wt or mutant p16 genes in the osteosarcoma cell line, U20S, which lacks p16 and retains functional retinoblastoma protein (pRb). "
03/01/1992 - "Further studies confirmed that the underphosphorylated Rb protein (p105Rb) present in G1 lysates of synchronized human MG63 osteosarcoma cells could be readily phosphorylated by purified PDPK in vitro, resulting in the characteristic shift in the apparent molecular mass (SDS-PAGE) of the Rb protein that is reported to accompany the hyperphosphorylation and functional inactivation of this protein. "
01/01/2010 - "A role for the retinoblastoma protein as a regulator of mouse osteoblast cell adhesion: implications for osteogenesis and osteosarcoma formation."
08/01/2007 - "Different effects of ribosome biogenesis inhibition on cell proliferation in retinoblastoma protein- and p53-deficient and proficient human osteosarcoma cell lines."
11/01/2006 - "The retinoblastoma protein in osteoblast differentiation and osteosarcoma."
|2.||Proteins (Proteins, Gene)
|4.||Messenger RNA (mRNA)
|6.||erucylphospho- N,N,N- trimethylpropylammonium
|8.||Glutathione S-Transferase pi
|9.||Multidrug Resistance-Associated Proteins
|1.||Drug Therapy (Chemotherapy)
|2.||Heterologous Transplantation (Xenotransplantation)