Spina Bifida Occulta

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40 relevant articles (2 outcomes, 1 trials/studies) found for this Disease

Description: A common congenital midline defect of fusion of the vertebral arch without protrusion of the spinal cord or meninges. The lesion is also covered by skin. L5 and S1 are the most common vertebrae involved. The condition may be associated with an overlying area of hyperpigmented skin, a dermal sinus, or an abnormal patch of hair. The majority of individuals with this malformation are asymptomatic although there is an increased incidence of tethered cord syndrome and lumbar SPONDYLOSIS. (From Joynt, Clinical Neurology, 1992, Ch55, p34)

Also Known As:

Occult Spina Bifida; Closed Spinal Bifida; Sinus, Dermal; Spina Bifida, Occult; Dermal Sinus; Spinal Bifida, Closed

Relationship Network

Disease Context: Research Results

Nervous System Diseases: 3406

Nervous System Malformations: 21

Neural Tube Defects: 2918

Spinal Dysraphism: 823

Spina Bifida Occulta: 40

Congenital, Hereditary, and Neonatal Diseases and Abnormalities: 420

Congenital Abnormalities: 9308

Nervous System Malformations: 21

Neural Tube Defects: 2918

Spinal Dysraphism: 823

Spina Bifida Occulta: 40

Related Diseases

1.	Neural Tube Defects (Exencephaly)
2.	Abscess
3.	Meningitis
4.	Congenital Abnormalities (Deformity)
5.	Dermoid Cyst (Dermoid)
32 Diseases and 23 more articles analyzed in the Research Interface, order at left...

Experts

1.	Duru, S: 1 article (03/2001)
2.	Ceylan, S: 1 article (03/2001)
3.	Briner, W: 1 article (01/2001)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Spina Bifida Occulta:

1.	VitaminsIBA 04/01/1992 - "A combination of the three vitamins was effective in reducing VPA-induced exencephaly (23-30%), spina bifida occulta (60%), and palate and rib malformations" Get all the results and reference details, order at left...
2.	PlasticsIBA 12/01/1999 - "The nasal dermal sinus cyst is one of many midline nasal masses that often pose diagnostic and treatment dilemmas for the plastic and reconstructive surgeon" 10/01/1999 - "The nasal dermal sinus cyst is one of many midline nasal masses that often pose diagnostic and treatment dilemmas for the plastic and reconstructive surgeon" 10/01/1999 - "The nasal dermal sinus cyst is one of many midline nasal masses that often pose diagnostic and treatment dilemmas for the plastic and reconstructive surgeon" Get all the results and reference details, order at left...
3.	Metrizamide FDA Link 09/01/1984 - "On examination, there was a dermal sinus in the skin overlying the spine of the seventh cervical vertebra, and myelography with computed tomography scan demonstrated a block to the flow of metrizamide contrast material at T-5 with cephalad extension of an intradural cystic lesion to the C-5 level" 10/01/1980 - "Congenital thoracic dermal sinus: diagnosis by computer assisted metrizamide myelography." Get all the results and reference details, order at left...
4.	Triad FDA Link 12/01/2000 - "Patients 2 and 3 are cousins whose fathers are affected by spina bifida occulta and Currarino triad, respectively" 11/01/1993 - "The main findings include--in addition to the classical congenital fusion of cervical vertebrae and the clinical triad of short neck, limitation of head and neck movement and low-set posterior hairline--several associated abnormalities: scoliosis, spina bifida occulta, absence of ribs, conductive hearing loss, mirror movements, unilateral renal ectopia with dilation of the collecting system, and microtia" Get all the results and reference details, order at left...
5.	Direction compoundIBA 05/01/2006 - "Interestingly, different from other dermal sinuses, the dermal sinus runs to caudal direction, and was fused filum terminale with dermoid cyst" 09/01/2002 - "Magnetic resonance (MR) imaging revealed a dermal sinus tract in the cranial direction to a cystic tumor at L2-4 levels" Get all the results and reference details, order at left...
6.	Vitamin B 6IBA 04/01/1992 - "On the other hand, vitamin B6 + vitamin B12 significantly reduced VPA-induced exencephaly (23%), spina bifida occulta (80%), palate and rib malformations, kidney abnormalities, and fetal weight retardation" Get all the results and reference details, order at left...
7.	Platelet-Derived Growth Factor alpha ReceptorIBA 11/24/1998 - "Mice heterozygous for the PDGFRalpha-mutation Patch, and at the same time homozygous for the undulated mutation in the Pax1 gene, exhibit a high incidence of lumbar spina bifida occulta, suggesting a functional relation between PDGFRalpha and Pax1" Get all the results and reference details, order at left...
8.	Gadolinium DTPA (Magnevist)FDA Link 09/01/1991 - "Gadopentetate dimeglumine-enhanced MR imaging of spinal dermal sinus tract." Get all the results and reference details, order at left...
9.	CA-15-3 Antigen (CA 15-3 Antigen)IBA 09/01/2007 - "METHODS: The tethering tract in 20 patients with spina bifida occulta underwent histological examination with H & E staining and epithelial membrane antigen (EMA) immunolabeling, and additional selected specimens were stained with Masson trichrome" Get all the results and reference details, order at left...
10.	GABA Receptors (GABA Receptor)IBA 01/01/2001 - "The effect of GABA receptor ligands in experimental spina bifida occulta." Get all the results and reference details, order at left...
22 Drugs and Important Bio-Agents and 23 more articles analyzed in the Research Interface, order at left...

Therapies and Procedures

1.	Laminectomy 12/16/1967 - "Results of treatment of progressive lesions in spina bifida occulta five to ten years after laminectomy." 06/01/1977 - "A patient suffering from intramedullary spinal cord abscess associated with an infected dermal sinus, meningitis, and low-lying spinal cord, underwent laminectomy and drainage, after which there was marked improvement" 08/01/2008 - "Total excision of dermal sinus tract, dermoid cyst, and the intramedullary abscess by means of a L2-S3 laminectomy, followed by antibiotic therapy resulted in good functional recovery" Get all the results and reference details, order at left...
2.	Lasers (Laser) 08/01/1999 - "During investigations preceding a trial of laser reflexo therapy in functional enuretic children aged 7 to 10 years spina bifida occulta was observed in 86.6% of subjects" 08/01/1999 - "Incidental spina bifida occulta in functional enuresis observed during laser reflexo therapy." Get all the results and reference details, order at left...
3.	X-Ray Film 01/01/2007 - "RESULTS: On plain X-ray films of the spine, spina bifida occulta (lumbar vertebrae in three, lumbosacral vertebrae in 19 and sacral vertebrae in 31) was recognized in 53 children (69%)" 06/01/1995 - "Cervical spine x-ray films showed occult spina bifida from C-1 to T-1 associated with an abnormal long club-like bone located parallel to the epidural space between C-5 and C-7" 01/01/1991 - "The cadaveric case presented describes plain film radiographic and anatomical findings of spina bifida occulta at the first and second sacral levels, and an enlarged spinous process of the fifth lumbar vertebra, in a 78 year old male cadaver with a tethered spinal cord terminating at the first sacral level" Get all the results and reference details, order at left...
4.	Rhinoplasty 12/01/1999 - "A comprehensive discussion of the pathogenesis, diagnosis, sequelae, and surgical management, and a representative case analysis, of the nasal dermal sinus cyst is presented to delineate the role of open rhinoplasty in optimizing the care of this congenital nasal deformity." 10/01/1999 - "A comprehensive discussion of the pathogenesis, diagnosis, sequelae, and surgical management, and a representative case analysis, of the nasal dermal sinus cyst is presented to delineate the role of open rhinoplasty in optimizing the care of this congenital nasal deformity." 10/01/1999 - "A comprehensive discussion of the pathogenesis, diagnosis, sequelae, and surgical management, and a representative case analysis, of the nasal dermal sinus cyst is presented to delineate the role of open rhinoplasty in optimizing the care of this congenital nasal deformity." Get all the results and reference details, order at left...
5.	Spinal Anesthesia 05/01/1998 - "With exact anatomical findings of MRI, spinal anesthesia can be safely performed for patients with spina bifida occulta." 05/01/1998 - "A 32-year-old woman with spina bifida occulta was scheduled for hemorroidectomy under spinal anesthesia" 05/01/1998 - "Spinal anesthesia in a patient with spina bifida occulta]" 10/01/1997 - "Spinal hematoma following spinal anesthesia in a patient with spina bifida occulta." 12/01/1959 - "Occult spina bifida and neurological disorders in spinal anesthesia" Get all the results and reference details, order at left...
12 Therapies and Procedures and 20 more articles analyzed in the Research Interface, order at left...

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