|2.||Neural Tube Defects (Exencephaly)
|3.||Neurogenic Urinary Bladder (Bladder, Neurogenic)
|4.||Chronic Kidney Failure (Chronic Renal Failure)
|5.||Prostatic Neoplasms (Prostate Cancer)
|1.||Shaw, Gary M: 30 articles (11/2015 - 02/2002)|
|2.||Finnell, Richard H: 16 articles (09/2013 - 02/2002)|
|3.||Zhu, Huiping: 15 articles (09/2013 - 02/2002)|
|4.||Lammer, Edward J: 15 articles (02/2009 - 02/2002)|
|5.||Mitchell, Laura E: 14 articles (01/2015 - 11/2002)|
|6.||Yang, Wei: 13 articles (11/2015 - 06/2005)|
|7.||Oakley, Godfrey P: 13 articles (09/2015 - 01/2002)|
|8.||Canfield, Mark A: 11 articles (11/2012 - 01/2002)|
|9.||Whitehead, Alexander S: 10 articles (08/2010 - 11/2002)|
|10.||Werler, Martha M: 9 articles (02/2014 - 01/2005)|
|1.||Folic Acid (Vitamin M)FDA LinkGeneric
09/01/2011 - "Using SINASC data, there was a significant reduction in spina bifida birth prevalence in Brazil, probably related to the folic acid food fortification program."
03/01/2006 - "Infants with spina bifida experienced a significantly improved first-year survival rate of 92.1% (adjusted hazard ratio: 0.68; 95% confidence interval: 0.50-0.91) during the period of mandatory folic acid fortification, compared with a 90.3% survival rate for those born before fortification. "
12/01/2000 - "Moreover, folic acid supplementation seems at least as effective in spina bifida patients as in controls."
10/01/2009 - "1. On the basis of own investigations the authors did not find positive results of introducing of women' s folic acid prophylaxis programme in Poland in the decrease of number of newborns, treated surgically on spina bifida in the Institute of Mother and Child. "
01/01/2016 - "In studies of live births (LBs) alone, period prevalences of spina bifida were (1) lower in geographical regions with mandatory (33.86 per 100 000 LBs) versus voluntary (48.35 per 100 000 LBs) folic acid fortification, and (2) lower in studies of LBs, stillbirths, and terminations of pregnancy in regions with mandatory (35.22 per 100 000 LBs) versus voluntary (52.29 per 100 000 LBs) fortification. "
02/01/1998 - "Therefore we did a follow-up study in the high risk group of patients with spina bifida and evaluated the efficacy of latex prophylaxis. "
06/01/2008 - "Spina bifida is often identified in utero or soon after birth, allowing vigorous latex allergen avoidance with enhanced efficacy of primary prevention. "
03/01/2002 - "Efficacy of latex avoidance for primary prevention of latex sensitization in children with spina bifida."
03/01/2012 - "Using novel latex extracts, our study showed a different in vivo reactivity pattern in health care workers and in patients with spina bifida to extracts of the internal and external surfaces of gloves, which suggests that sensitization may occur by different routes of exposure, and that this influences the allergen reactivity profiles of these risk groups."
12/01/2010 - "To study the effect of primary latex-free prophylaxis on the prevalence of allergic diseases and atopy as a marker for sensitization spreading in children with spina bifida. "
|3.||Immunoglobulin E (IgE)IBA
06/01/2007 - "We investigated the prevalence of NRL-specific IgE (> 0.35 kU/l, ImmunoCAP system, Pharmacia) in a normal paediatric population (neither atopic nor having undergone surgery) (group I), spina bifida patients (group II), children with urogenital malformations (group III) and children with oesophago-tracheal malformations (group IV). "
05/01/2000 - "Intermethod comparison of in vitro and in vivo IgE assays in spina bifida patients."
10/01/1996 - "The pattern of reactivity was not correlated specifically with IgE levels, but sera from patients suffering from spina bifida reacted specifically with the minor protein of 25 kDa located in LP. "
01/01/1996 - "Further, 2 of 11 spina bifida patients found to be NL-IgE negative by FCA were NL-IgE positive by ECL. "
12/01/1992 - "Rubber-specific IgE in children with spina bifida: identification and management."
01/01/2007 - "Abnormalities like decreased number of embryos, growth delay, spina bifida and sinus arrhythmia from 12th GD were documented in pups of mice showing anti-5-HT4 receptor antibodies. "
08/01/2000 - "Analysis by the CAP system revealed the presence of rHev b 8-specific IgE antibodies in two out of 17 sera from spina bifida patients and in five out of 25 sera (20%) from health-care workers. "
09/01/1998 - "We found significant correlation between duration of SCL and precipitating antibodies against urinary tract pathogens (PAU) (r = 0.23, P < 0.005), between plasma creatinine and PAU in patients with spina bifida (r = 0.64, P < 0.01), between PAU and the number of positive urine cultures (r = 0.17; P < 0.05) and a relation between abnormal urological findings and PAU. "
01/01/1998 - "The high prevalence of latex antibodies in children with spina bifida justifies a primary prophylaxis by avoiding latex contacts, especially during anaesthesia and surgery, a correlation between the number of operations and the development of latex antibodies exists."
01/01/1998 - "Antibodies against banana were more frequent in the latex sensitized children with spina bifida. "
09/01/2002 - "Although D-chiro- and myo-inositol both reduced the frequency of spina bifida in curly tail mice by all routes of administration, D-chiro-inositol consistently exhibited the more potent effect, reducing spina bifida by 73-86% in utero compared with a 53-56% reduction with myo-inositol. "
02/15/2008 - "In this study, we present a Fkbp8 mouse mutant that has an isolated and completely penetrant spina bifida, which is folate- and inositol-resistant. "
07/01/2009 - "Stepwise multiple logistic regression analysis showed that high maternal glucose and low myo-inositol are the main risk factors for H2 spina bifida children, whereas for H1 spina bifida children, maternal BMI was the main risk factor. "
04/01/2009 - "Spina bifida frequency is reduced in Axd by methionine and in curly tail by inositol. "
06/01/2004 - "We investigated the biochemical concentrations of these nutrients and polymorphisms in the myo-inositol transporter SLC5A11, myo-inositol synthase ISYNA1, and zinc transporter SLC39A4 in association with spina bifida risk. "
|6.||Tretinoin (Retinoic Acid)FDA LinkGeneric
06/01/2015 - "Induced coverage of spina bifida by TRASCET minimizes the Chiari-II malformation in the retinoic acid rodent model, further suggesting it as a practical alternative for the prenatal management of spina bifida."
06/01/2015 - "Sprague-Dawley fetuses (n=62) exposed to retinoic acid were divided into three groups at term (21-22 days gestation): untreated isolated spina bifida (n=21), isolated spina bifida treated with intra-amniotic injection of concentrated, syngeneic, labeled amniotic fluid mesenchymal stem cells (afMSCs) on gestational day 17 (n=28), and normal controls (n=13). "
08/01/2012 - "Here, we investigated cell apoptosis in whole embryos and proliferation of neural progenitor cells in the spinal neural tube during neurulation in all-trans retinoic acid (atRA)-induced spina bifida in fetal rats. "
04/01/2003 - "We have previously reported that the retinoic acid (RA) catabolizing enzyme CYP26A1 plays an important role in protecting tail bud tissues from inappropriate exposure to RA generated in the adjacent trunk tissues by RALDH2, and that Cyp26a1-null animals exhibit spina bifida and caudal agenesis. "
05/01/2002 - "We provide genetic evidence that ALDH1A2 and CYP26A1 activities concurrently establish local embryonic retinoic acid levels that must be finely tuned to allow posterior organ development and to prevent spina bifida."
|7.||L 644711 (B-3(+))IBA
04/15/2000 - "Characterization of T cell responses to Hev b 3, an allergen associated with latex allergy in spina bifida patients."
11/01/1999 - "Cloning, expression, and characterization of recombinant Hev b 3, a Hevea brasiliensis protein associated with latex allergy in patients with spina bifida."
01/01/2001 - "Development of recombinant Hev b 3, a major NRL allergen relevant to children with spina bifida, enhances the likelihood for improved diagnostic reagents. "
05/01/2002 - "In addition, Hev b 3 and Hev b 1, the two major allergens for children with spina bifida, are also commonly found. "
02/01/1999 - "Cloning and molecular characterization of Hev b 3, a spina-bifida-associated allergen from Hevea brasiliensis latex."
03/01/1994 - "The affinity-purified antigen of CRI-C (C-Ag) had multiple bands of less than 20 kd and was 3.9 times more potent in RAST inhibition than NAL when sera from patients with spina bifida were used. "
09/01/1993 - "Also no relationship between spina bifida and red blood cell antigens. "
04/30/1980 - "The geographical correlations between the mortality rates of Spina-Bifida and incidence of Spina-Bifida and Anencephaly and the HLA antigen frequencies are studied. "
03/01/1980 - "The geographical correlation between the incidence of spina bifida and anencephaly and the HLA and ABO antigen frequencies are studied. "
08/01/1991 - "Children with spina bifida have a significantly greater likelihood than controls of having IgE specific for rubber antigens. "
02/01/2008 - "Correlation between cystatin C- and renal scan-determined glomerular filtration rate in children with spina bifida."
06/01/2003 - "Cystatin C proved to be a superior marker in patients with spina bifida. "
06/01/2003 - "Only cystatin C served as a suitable marker to estimate glomerular filtration rate in patients with spina bifida. "
06/01/2003 - "Correlation coefficients for cystatin C were 0.45 and 0.84 in the spina bifida and control groups, respectively, while correlation coefficients for beta-trace protein were 0.31 and 0.75, respectively. "
06/01/2003 - "Measuring glomerular filtration rate with cystatin C and beta-trace protein in children with spina bifida."
|10.||Tetrahydrofolate Dehydrogenase (Dihydrofolate Reductase)IBA
06/01/2007 - "The 19-bp deletion polymorphism in intron-1 of dihydrofolate reductase (DHFR) may decrease rather than increase risk for spina bifida in the Irish population."
05/01/2007 - "Variation and expression of dihydrofolate reductase (DHFR) in relation to spina bifida."
02/01/2004 - "New 19 bp deletion polymorphism in intron-1 of dihydrofolate reductase (DHFR): a risk factor for spina bifida acting in mothers during pregnancy?"
01/01/2010 - "Dihydrofolate reductase gene (DHFR) 19-bp deletion polymorphisms result in varied DHFR enzymatic activity affecting the risk for preterm delivery, spina bifida, and the efficacy of methotrexate (MTX). "
08/01/1975 - "A study of ankle X-rays of spina bifida children before and after extra-articular subtalar fusion in which the bone graft is removed from the ipsilateral tibia has shown that the valgus tilt of the mortice may increase after this procedure."
08/01/2006 - "However, in patients with a renal transplant or spina bifida, the 2 new equations were less biased and more precise. "
02/01/2002 - "Between February 1986 and April 2000, 17 cadaveric renal transplants were performed in 11 females and 5 males with spina bifida. "
09/01/1994 - "Between February 1989 and December 1991, we performed 5 cadaveric renal transplants in 4 patients with spina bifida. "
01/01/2013 - "We report our management of a renal transplant patient with spina bifida, who was diagnosed with stage IIIC, poor-risk, non-seminomatous germ cell carcinoma. "
|2.||Intermittent Urethral Catheterization
03/01/2011 - "The need for clean intermittent catheterization was the only medical factor associated with parenting stress in mothers of children with spina bifida. "
06/01/2008 - "This means that new patients with spina bifida should be treated from birth by clean intermittent catheterization and pharmacological suppression of detrusor overactivity. "
06/01/2004 - "Complications associated with clean intermittent catheterization in children with spina bifida."
01/01/1999 - "To evaluate a population of adult spina bifida patients performing clean intermittent catheterization (CIC) and determine the indications for urologic consultation and intervention. "
11/01/1997 - "Retrospective analyses were performed to elucidate the clinical significance between Credé voiding (n = 56) and Valsalva voiding (n = 22) in the urological management of spina bifida patients who do not match the indication of clean intermittent catheterization. "
|3.||Urinary Diversion (Ileal Conduit)
07/01/2011 - "All patients who underwent bladder augmentation or ileal conduit diversion between 1998 and 2005 with a diagnosis consistent with spina bifida were included in the study. "
07/01/2011 - "Therefore, we characterized the use of bladder augmentation and urinary diversion in patients with spina bifida in a nationally representative, all payer, all ages data set. "
07/01/2011 - "Bladder augmentation versus urinary diversion in patients with spina bifida in the United States."
08/01/2004 - "Vaginal delivery in a patient with spina bifida and a Mitrofanoff urinary diversion."
11/01/2002 - "Pregnancy in patients with spina bifida and urinary diversion."
12/01/2013 - "This study assessed the effects of pulsed Nd:YAG laser treatment of neuropathic foot ulcers in children with spina bifida. "
12/01/2013 - "Effect of pulsed Nd:YAG laser in the treatment of neuropathic foot ulcers in children with spina bifida: a randomized controlled study."
12/01/2011 - "Faun tail nevus and spinal dysraphism: cosmetic improvement with alexandrite laser epilation."
12/01/2013 - "Treatment with pulsed neodymium:yttrium aluminum garnet (Nd:YAG) laser combined with standard wound care decreases wound size and improves wound appearance for stage III neuropathic foot ulcers in children with spina bifida."
12/01/2011 - "A total of 176 patients with spina bifida participated in a randomized controlled trial (ISRCTN trial number 56278131) of either continuation or discontinuation of low dose chemoprophylaxis. "
12/01/2011 - "Antibiotic prophylaxis (low dose chemoprophylaxis) has been prescribed since the introduction of clean intermittent catheterization in children with spina bifida. "
04/01/2009 - "The introduction of clean intermittent catheterization (CIC) in 1972 and low-dose chemoprophylaxis (LDCP, antibiotic prophylaxis), anticholinergic medication and urological surgery in the mid-1980s has improved the long-term outcome of renal function in children with neurogenic bladder sphincter dysfunction (NBSD) due to spina bifida (SB). "