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Spinal Fractures

Broken bones in the vertebral column.
Also Known As:
Fracture, Spinal; Fractures, Spinal; Spinal Fracture
Networked: 208 relevant articles (14 outcomes, 28 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Pain (Aches)
2. Spinal Stenosis (Stenosis, Spinal)
3. Osteoporosis
4. Prostatic Neoplasms (Prostate Cancer)
5. Neoplasm Metastasis (Metastasis)

Experts

1. Leferink, V J M: 4 articles (10/2004 - 02/2002)
2. Reginster, Jean-Yves: 3 articles (02/2006 - 04/2004)
3. ten Duis, H J: 3 articles (06/2003 - 12/2001)
4. Zimmerman, K W: 3 articles (06/2003 - 12/2001)
5. Zou, Jun: 2 articles (10/2014 - 07/2010)
6. Gan, Minfeng: 2 articles (10/2014 - 07/2010)
7. Yang, Huilin: 2 articles (10/2014 - 07/2010)
8. Wang, Yan: 2 articles (06/2013 - 05/2010)
9. Osborne, Richard H: 2 articles (11/2009 - 10/2006)
10. Buchbinder, Rachelle: 2 articles (11/2009 - 10/2006)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Spinal Fractures:
1. Heparin (Liquaemin)FDA LinkGeneric
2. zoledronic acid (zoledronate)FDA Link
01/01/2008 - "A multi-centered observational study evaluated the efficacy of zoledronic acid for improving pain and mobility, and preventing skeletal-related events (SRE) (fracture, spinal compression, pain-relieving radiotherapy), in patients with prostate cancer and bone metastasis. "
08/01/2012 - "The search for evidence was based on real clinical scenarios, and used the following keywords (MeSH terms): Osteoporosis, Osteoporosis/ chemically induced*= (Glucocorticoids= Adrenal Cortex Hormones, Steroids), Glucocorticoids, Glucocorticoids/administration and dosage, Glucocorticoids/therapeutic use, Glucocorticoids/adverse effects, Prednisone/adverse effects, Dose-Response Relationship, Drug, Bone Density/drug effects, Bone Density Conservation Agents/pharmacological action, Osteoporosis/prevention & control, Calcium, Vitamin D, Vitamin D deficiency, Calcitriol, Receptors, Calcitriol; 1-hydroxycholecalciferol, Hydroxycholecalciferols, 25-Hydroxyvitamin D3 1-alpha-hydroxylase OR Steroid Hydroxylases, Prevention and Control, Spinal fractures/prevention & control, Fractures, Spontaneous, Lumbar Vertebrae/injuries, Lifestyle, Alcohol Drinking, Smoking OR tobacco use disorder, Movement, Resistance Training, Exercise Therapy, Bone density OR Bone and Bones, Dual-Energy X-Ray Absorptiometry OR Absorptiometry Photon OR DXA, Densitometry, Radiography, (Diphosphonates Alendronate OR Risedronate Pamidronate OR propanolamines OR Ibandronate OR Zoledronic acid, Teriparatide OR PTH 1-34, Men AND premenopause, pregnancy, pregnancy outcome maternal, fetus, lactation, breast-feeding, teratogens, Children (6-12 years), adolescence (13-18 years). "
3. Dalteparin (Dalteparin Sodium)FDA Link
4. Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA
5. FluoridesIBA
6. Parathyroid Hormone (Parathormone)IBA
7. pamidronate (APD)FDA LinkGeneric
09/01/2012 - "Here, a case of a 9-year-old girl with familial HCS and multiple spinal fractures, who has been effectively treated with pamidronate, is presented. "
08/01/2012 - "The search for evidence was based on real clinical scenarios, and used the following keywords (MeSH terms): Osteoporosis, Osteoporosis/ chemically induced*= (Glucocorticoids= Adrenal Cortex Hormones, Steroids), Glucocorticoids, Glucocorticoids/administration and dosage, Glucocorticoids/therapeutic use, Glucocorticoids/adverse effects, Prednisone/adverse effects, Dose-Response Relationship, Drug, Bone Density/drug effects, Bone Density Conservation Agents/pharmacological action, Osteoporosis/prevention & control, Calcium, Vitamin D, Vitamin D deficiency, Calcitriol, Receptors, Calcitriol; 1-hydroxycholecalciferol, Hydroxycholecalciferols, 25-Hydroxyvitamin D3 1-alpha-hydroxylase OR Steroid Hydroxylases, Prevention and Control, Spinal fractures/prevention & control, Fractures, Spontaneous, Lumbar Vertebrae/injuries, Lifestyle, Alcohol Drinking, Smoking OR tobacco use disorder, Movement, Resistance Training, Exercise Therapy, Bone density OR Bone and Bones, Dual-Energy X-Ray Absorptiometry OR Absorptiometry Photon OR DXA, Densitometry, Radiography, (Diphosphonates Alendronate OR Risedronate Pamidronate OR propanolamines OR Ibandronate OR Zoledronic acid, Teriparatide OR PTH 1-34, Men AND premenopause, pregnancy, pregnancy outcome maternal, fetus, lactation, breast-feeding, teratogens, Children (6-12 years), adolescence (13-18 years). "
8. DNA Transposable Elements (Element, IS)IBA
9. Vitamin DFDA LinkGeneric
10. DiphosphonatesIBA

Therapies and Procedures

1. Decompression
2. Vertebroplasty
3. Kyphoplasty
4. Radiotherapy
5. Spinal Fusion (Spondylosyndesis)