Ethylene Dibromide (1,2 Dibromoethane)

An effective soil fumigant, insecticide, and nematocide. In humans, it causes severe burning of skin and irritation of the eyes and respiratory tract. Prolonged inhalation may cause liver necrosis. It is also used in gasoline. Members of this group have caused liver and lung cancers in rodents. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), 1,2-dibromoethane may reasonably be anticipated to be a carcinogen.
Also Known As:
1,2 Dibromoethane; 1,2-Dibromoethane; Dowfume W 85; Dowfume W85; Ethylene Bromide; Ethylene Dibromides; sym-Dibromoethane; Bromide, Ethylene; Dibromide, Ethylene; Dibromides, Ethylene; sym Dibromoethane; Ethane, 1,2-dibromo-
Networked: 40 relevant articles (1 outcomes, 4 trials/studies)

Relationship Network

Bio-Agent Context: Research Results


1. Peng, Lin: 1 article (10/2015)
2. Cheng, Na: 1 article (10/2015)
3. Mu, Ling: 1 article (10/2015)
4. Bai, Huiling: 1 article (10/2015)
5. Yan, Yulong: 1 article (10/2015)
6. Jain, Manish: 1 article (10/2013)
7. Kosta, Susmit: 1 article (10/2013)
8. Argal, Suarabh: 1 article (10/2013)
9. Pahwa, Naresh: 1 article (10/2013)
10. Bharani, Rajesh: 1 article (10/2013)

Related Diseases

1. Dehydration (Water Stress)
2. Neoplasms (Cancer)
3. Hyperplasia
06/01/1993 - "We show here that whereas c-fos and c-jun expression increased soon after partial hepatectomy or carbon tetrachloride administration, an increased expression of c-jun in the absence of c-fos expression occurred during direct hyperplasia induced by lead nitrate and ethylene dibromide. "
05/01/1990 - "Experiments were designed to investigate the expression of three cell-cycle-dependent proto-oncogenes in response to two different types of proliferative stimuli: compensatory cell proliferation after partial hepatectomy (PH) or CCl4 and liver hyperplasia induced by the mitogens ethylene dibromide (EDB) and cyproterone acetate (CPA). "
05/01/1993 - "The inability of direct hyperplasia to stimulate the development of enzyme-altered hepatic foci was not unique to lead nitrate since the same phenomenon was observed when three other hepatomitogens, nafenopin, cyproterone acetate, and ethylene dibromide, were used."
05/01/1990 - "After a 2-week recovery period liver cell proliferation was repeatedly induced by four or eight necrogenic doses of carbon tetrachloride (compensatory cell proliferation), or by four or eight treatments with three different liver mitogens, namely lead nitrate, ethylene dibromide and nafenopin (direct hyperplasia). "
05/01/1989 - "Our earlier studies have revealed that direct hyperplasia induced by liver mitogens such as lead nitrate, ethylene dibromide, nafenopin and cyproterone acetate, unlike compensatory cell proliferation induced by partial hepatectomy and CCl4, does not support the formation of enzyme-altered islands induced by chemical carcinogens in the liver. "
4. Poisoning
5. Aspermia

Related Drugs and Biologics

1. Nafenopin
2. Cyproterone Acetate
3. lead nitrate
4. Mitogens
5. Carcinogens
6. Benzene (Benzole)
7. 1,2-dibromo-3-chloropropane (DBCP)
8. Epichlorohydrin (Epichlorhydrin)
9. 1,3-butadiene
10. propylene oxide

Related Therapies and Procedures

1. Hepatectomy
2. Plasma Exchange
3. Oral Administration