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Factor XIa (Coagulation Factor XIa)

Activated form of factor XI. In the intrinsic pathway, Factor XI is activated to XIa by factor XIIa in the presence of cofactor HMWK; (HIGH MOLECULAR WEIGHT KININOGEN). Factor XIa then activates factor IX to factor IXa in the presence of calcium.
Also Known As:
Coagulation Factor XIa; Activated Factor XI; Blood Coagulation Factor XI, Activated; Contact Activation Product; Factor XIa, Coagulation; XIa, Coagulation Factor; Factor XI, Activated
Networked: 40 relevant articles (2 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Butenas, Saulius: 5 articles (04/2012 - 01/2008)
2. Undas, Anetta: 5 articles (04/2012 - 01/2008)
3. Gailani, David: 4 articles (09/2014 - 08/2006)
4. Tuma, Ronald F: 2 articles (02/2013 - 07/2012)
5. Navaneetham, Duraiswamy: 2 articles (02/2013 - 07/2012)
6. Wu, Wenman: 2 articles (02/2013 - 07/2012)
7. Walsh, Peter N: 2 articles (02/2013 - 07/2012)
8. Li, Hongbo: 2 articles (02/2013 - 07/2012)
9. Travers, Richard J: 1 article (09/2015)
10. Diamond, Scott L: 1 article (09/2015)

Related Diseases

1. Hemorrhage
2. Hemophilia B (Haemophilia B)
3. Thrombosis (Thrombus)
4. Acute Coronary Syndrome
5. Hereditary Angioedemas

Related Drugs and Biologics

1. Fibrinolytic Agents (Antithrombotic Agents)
2. Factor IX (PTC)
3. Thromboplastin (Tissue Factor)
4. Thrombin
5. Factor XIIa (Coagulation Factor XIIa)
6. Protease Inhibitors (Protease Inhibitor)
7. Factor XI (Plasma Thromboplastin Antecedent)
8. Factor VIII (Coagulation Factor VIII)
9. Calcium
10. alpha 1-Antitrypsin (alpha 1 Antitrypsin)