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Complement C3a (Complement 3a)

The smaller fragment generated from the cleavage of complement C3 by C3 CONVERTASE. C3a, a 77-amino acid peptide, is a mediator of local inflammatory process. It induces smooth MUSCLE CONTRACTION, and HISTAMINE RELEASE from MAST CELLS and LEUKOCYTES. C3a is considered an anaphylatoxin along with COMPLEMENT C4A; COMPLEMENT C5A; and COMPLEMENT C5A, DES-ARGININE.
Also Known As:
Complement 3a; C3a Complement; Complement Component 3a; C3a, Complement; Complement, C3a; Component 3a, Complement
Networked: 43 relevant articles (3 outcomes, 1 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Monk, Peter N: 2 articles (12/2014 - 05/2012)
2. Woodruff, Trent M: 2 articles (12/2014 - 05/2012)
3. Floudas, Christodoulos A: 2 articles (12/2014 - 05/2012)
4. Morikis, Dimitrios: 2 articles (12/2014 - 05/2012)
5. Bellows-Peterson, Meghan L: 2 articles (12/2014 - 05/2012)
6. Kieslich, Chris A: 2 articles (12/2014 - 05/2012)
7. Connolly, E Sander: 2 articles (09/2011 - 08/2007)
8. Meinert, H: 2 articles (01/2001 - 01/2001)
9. Northoff, H: 2 articles (01/2001 - 01/2001)
10. Röhlke, W: 2 articles (01/2001 - 01/2001)

Related Diseases

1. Necrosis
2. Ischemia
3. Lung Injury
4. Amnesia (Dissociative Amnesia)
5. Systemic Inflammatory Response Syndrome (Sepsis Syndrome)

Related Drugs and Biologics

1. Interleukins
2. Cytokines
3. Scopolamine (Hyoscine)
4. Interferons
5. thymidine 5'-triphosphate (TTP)
6. C-Reactive Protein
7. Interleukin-6 (Interleukin 6)
8. procalcitonin
9. Anaphylatoxins
10. Anaphylatoxin C5a Receptor