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Heparin Cofactor II

A sulfated plasma protein with a MW of approximately 66kDa that resembles ANTITHROMBIN III. The protein is an inhibitor of thrombin in plasma and is activated by dermatan sulfate or heparin. It is a member of the serpin superfamily.
Also Known As:
Heparin Co-Factor II; Heparin Cofactor 2; Leuserpin 2; Protease Inhibitor Leuserpin 2; Serpin D1; Heparin Co Factor II; Heparin cofactor II
Networked: 148 relevant articles (3 outcomes, 15 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Tollefsen, Douglas M: 7 articles (07/2011 - 01/2002)
2. Matsumoto, Toshio: 5 articles (10/2012 - 06/2004)
3. Akaike, Masashi: 5 articles (10/2012 - 06/2004)
4. Sata, Masataka: 4 articles (10/2012 - 06/2007)
5. Aihara, Ken-ichi: 4 articles (10/2012 - 06/2004)
6. Ikeda, Yasumasa: 4 articles (10/2012 - 06/2004)
7. Azuma, Hiroyuki: 4 articles (10/2009 - 06/2004)
8. Iwase, Takashi: 3 articles (10/2012 - 06/2007)
9. Vicente, Cristina P: 3 articles (07/2011 - 01/2002)
10. Mourão, Paulo A S: 3 articles (05/2011 - 01/2004)

Related Diseases

1. Atherosclerosis
2. Infection
3. Septic Shock (Toxic Shock Syndrome)
4. Thrombosis (Thrombus)
5. Venous Thrombosis (Deep-Vein Thrombosis)

Related Drugs and Biologics

1. Serine Proteases (Serine Protease)
2. Protein S
3. Protein C
4. Thrombin
5. Antithrombin III
6. Prothrombin (Factor II)
7. Thrombomodulin
8. von Willebrand Factor
9. antithrombin III-protease complex
10. Heparin (Liquaemin)

Related Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Critical Care
3. Liver Transplantation
4. Bone Marrow Transplantation (Transplantation, Bone Marrow)
5. Stents