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Ocular Onchocerciasis (River Blindness)

Filarial infection of the eyes transmitted from person to person by bites of Onchocerca volvulus-infected black flies. The microfilariae of Onchocerca are thus deposited beneath the skin. They migrate through various tissues including the eye. Those persons infected have impaired vision and up to 20% are blind. The incidence of eye lesions has been reported to be as high as 30% in Central America and parts of Africa.
Also Known As:
River Blindness; Onchocerciasis, Ocular; Blindness, River; Ocular Onchocerciases; Onchocerciases, Ocular
Networked: 104 relevant articles (7 outcomes, 12 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Onchocerciasis
2. Infection
3. Body Weight (Weight, Body)
4. Keratitis
5. Inflammation

Experts

1. Pearlman, E: 6 articles (06/2012 - 07/2000)
2. Pearlman, Eric: 5 articles (04/2006 - 03/2002)
3. Hoerauf, Achim: 4 articles (04/2015 - 11/2002)
4. Basáñez, María-Gloria: 4 articles (04/2015 - 03/2007)
5. Diaconu, E: 4 articles (09/2007 - 11/2000)
6. Tanya, Vincent N: 3 articles (08/2015 - 01/2007)
7. Makepeace, Benjamin L: 3 articles (08/2015 - 01/2007)
8. Taylor, Mark J: 3 articles (04/2015 - 06/2003)
9. Specht, Sabine: 3 articles (04/2015 - 03/2013)
10. Churcher, Thomas S: 3 articles (04/2015 - 09/2009)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Ocular Onchocerciasis:
1. Ivermectin (Mectizan)FDA Link
2. Diethylcarbamazine (Hetrazan)FDA Link
3. Doxycycline (Vibramycin)FDA LinkGeneric
4. Ophthalmic Solutions (Eye Drops)IBA
5. CoffeeFDA Link
6. AntigensIBA
7. Suramin (Suramin Sodium)IBA
8. CytokinesIBA
9. Apolipoproteins C (ApoC)IBA
10. Interleukin-13IBA

Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Intravitreal Injections