|1.||Aggarwal, Nitin T: 1 article (07/2008)|
|2.||Campbell, William B: 1 article (07/2008)|
|3.||Gauthier, Kathryn M: 1 article (07/2008)|
|4.||Kelley, Glen L: 1 article (08/2005)|
|5.||Azhar, Salman: 1 article (08/2005)|
|6.||Muhuri, D: 1 article (06/2005)|
|7.||Gomes, A: 1 article (06/2005)|
|8.||Dasgupta, S C: 1 article (06/2005)|
|9.||Sherman, B E: 1 article (07/2000)|
|10.||Chole, R A: 1 article (07/2000)|
10/01/1982 - "BW755C produced a depressive effect on carrageenin-induced pleurisy, but on triple vaccine-induced pleurisy, BW755C produced only a slight depressive effect. "
01/01/1987 - "Both nonsteroidal anti-inflammatory drugs and a mixed lipoxygenase-cyclooxygenase inhibitor (BW 755C) preferentially inhibited fluid accumulation in RPAR pleurisy elicited with 5 mg BSA and 1 mg anti-BSA and in carrageenan pleurisy. "
03/01/1986 - "Furthermore, KME-4, when administered orally 5 h after the carrageenan, inhibited both monocyte numbers and exudate volume in a 24 h pleurisy and was more effective than indomethacin and BW755c which inhibited only monocyte migration. "
02/05/1982 - "In rat carrageenin pleurisy, dexamethasone (0.25 mg/kg p.o.) inhibited exudate accumulation in the pleural cavity throughout the period of testing while the non-steroidal anti-inflammatory drugs indomethacin (10 mg/kg p.o.) and BW755C (100 mg/kg p.o.) inhibited it for 6 and 9 h respectively after the intrapleural injection of carrageenin but not thereafter. "
02/05/1982 - "Comparison of the anti-inflammatory effects of dexamethasone, indomethacin and BW755C on carrageenin-induced pleurisy in rats."
10/01/1986 - "The Paf-induced haemoconcentration and plasma exudation were significantly reduced by pretreatment with prednisolone (20 mg kg-1 s.c.) or BW755C (50 mg kg-1 p.o.), while Paf-induced leukopenia was unaffected by either drug. "
10/01/1986 - "The mixed cyclo-oxygenase/lipoxygenase inhibitor compound BW 755C was very effective in blocking bronchoconstriction by the highest dose of FMLP used, but failed to interfere with leukopenia. "
01/01/1989 - "To determine whether invading leukocytes mediate these responses, acute inflammatory cell influx was suppressed either by inducing leukopenia with nitrogen mustard or by administration of BW-755C, a mixed cyclooxygenase-lipoxygenase inhibitor. "
01/01/1986 - "Ovalbumin challenge in sensitized guinea pigs in vivo resulted in airway constriction, circulatory failure and an abrupt fall in continuously measured platelet count by 75 +/- 12%, followed by death of all animals within 5-8 min. Pretreatment with diphenhydramine, BW-755C and kadsurenone (or alprazolam) improved survival to 64% (i.e., 7 of 11 animals) compared to a survival rate of 0% (i.e., 0 of 8 vehicle treated controls). "
01/01/1988 - "Experiments were carried out to lower the mortality (LD70-90) of rats in ovalbumin-induced anaphylactic (DA) shock and in endotoxin-induced (ET) shock, and of mice after injection of Platelet-activating Factor (PAF shock) comparing the effects of the cyclooxygenase (COX)-inhibitors aspirin (ASA), indomethacin, of the COX-/lipoxygenase (LOX)-inhibitors nordihydroguajaretic acid (NDGA), phenidone and X 86 (analogue of BW 755c), of the inhibitor of thromboxane (TX) synthesis HOE 944, of the TX-antagonist BM 13177, of the PAF-antagonist BN 52021 and of ketotifen. "
|4.||Myocardial Ischemia (Ischemic Heart Diseases)
05/23/1994 - "Application of the cyclooxygenase/lipoxygenase inhibitor BW755C (40 mg/kg i.p.) reduced the severity of seizures and protected significantly from irreversible brain lesions induced by KA. "
05/23/1994 - "The cyclooxygenase and lipoxygenase inhibitor BW755C protects rats against kainic acid-induced seizures and neurotoxicity."
|1.||Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)
|5.||Nordihydroguaiaretic Acid (Masoprocol)