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Almitrine (Vectarion)

A respiratory stimulant that enhances respiration by acting as an agonist of peripheral chemoreceptors located on the carotid bodies. The drug increases arterial oxygen tension while decreasing arterial carbon dioxide tension in patients with chronic obstructive pulmonary disease. It may also prove useful in the treatment of nocturnal oxygen desaturation without impairing the quality of sleep.
Also Known As:
Vectarion; Almitrine Bis(methanesulfonate); Almitrine Dimesylate; Almitrine Monomesylate; Euthérapie Brand of Almitrine Dimesilate; Servier Brand of Almitrine Dimesilate; Monomesylate, Almitrine; Almitrine Bismesylate; 1,3,5-Triazine-2,4-diamine, 6-(4-(bis(4-fluorophenyl)methyl)-1-piperazinyl)-N,N'-di-2-propenyl-
Networked: 285 relevant articles (27 outcomes, 52 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Dembinski, R: 4 articles (03/2001 - 02/2000)
2. Rossaint, R: 4 articles (03/2001 - 02/2000)
3. Max, M: 3 articles (03/2001 - 02/2000)
4. Kuhlen, R: 3 articles (03/2001 - 02/2000)
5. Dalibon, Nicolas: 2 articles (03/2004 - 04/2002)
6. Liu, Ngai: 2 articles (03/2004 - 04/2002)
7. Fischler, Marc: 2 articles (03/2004 - 04/2002)
8. Moutafis, Marc: 2 articles (03/2004 - 04/2002)
9. Pachocki, R: 2 articles (05/2003 - 09/2001)
10. Górecka, D: 2 articles (05/2003 - 09/2001)

Related Diseases

1. Chronic Obstructive Pulmonary Disease (COPD)
2. Anoxia (Hypoxia)
3. Obstructive Sleep Apnea
4. Respiratory Insufficiency (Respiratory Failure)
5. Peripheral Nervous System Diseases (PNS Diseases)

Related Drugs and Biologics

1. Gases
2. Nitric Oxide (Nitrogen Monoxide)
3. Almitrine (Vectarion)
4. Oxygen
5. Epoprostenol (Prostacyclin)
6. 2,4-bis(2-acetoxybenzamido)benzoic acid (AB 50)
7. Doxapram (Doxapram Hydrochloride)
8. Cyclooxygenase Inhibitors
9. Medroxyprogesterone Acetate (Depo-Provera)
10. Progesterone

Related Therapies and Procedures

1. Oral Administration
2. Artificial Respiration (Mechanical Ventilation)
3. Vagotomy
4. Positive-Pressure Respiration (PEEP)
5. Analgesia