Alfentanil (Alfenta)

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473 relevant articles (35 outcomes, 73 trials/studies) found for this Drug

Description: A short-acting opioid anesthetic and analgesic derivative of FENTANYL. It produces an early peak analgesic effect and fast recovery of consciousness. Alfentanil is effective as an anesthetic during surgery, for supplementation of analgesia during surgical procedures, and as an analgesic for critically ill patients.

Also Known As:

Alfenta; Alfentanil Hydrochloride; Esteve Brand of Alfentanil Hydrochloride; Fanaxal; ICI Brand of Alfentanil Hydrochloride; Janssen Brand of Alfentanil Hydrochloride; Limifen; R-39209; Rapifen; R 39209; R39209; Alfentanyl; Propanamide, N-(1-(2-(4-ethyl-4,5-dihydro-5-oxo-1H-tetrazol-1-yl)ethyl)-4-(methoxymethyl)-4-piperidinyl)-N-phenyl-

Relationship Network

Drug Context: Research Results

Heterocyclic Compounds: 23

1-Ring Heterocyclic Compounds

Piperidines: 7

Fentanyl: 2922

Alfentanil: 473

Experts

1.	Van Obbergh, Luc: 2 articles (01/2007 - 12/2005)
2.	Desager, Jean-Pierre: 2 articles (01/2007 - 12/2005)
3.	Wallemacq, Pierre: 2 articles (01/2007 - 12/2005)
4.	Horsmans, Yves: 2 articles (01/2007 - 12/2005)
5.	Walker, Alysa: 2 articles (10/2005 - 11/2004)
6.	Kharasch, Evan D: 2 articles (10/2005 - 11/2004)
7.	Sheffels, Pamela: 2 articles (10/2005 - 11/2004)
8.	Hoffer, Christine: 2 articles (10/2005 - 11/2004)
9.	Arendt-Nielsen, L: 2 articles (09/2003 - 07/2001)
10.	Gallagher, G: 2 articles (01/2001 - 12/2000)

Related Diseases

1.	Pain (Aches) 03/01/2001 - "The effects of alfentanil on cold and cold pain thresholds and spontaneous pain scores correlates with previous studies suggesting an opiate central analgesic effect" 11/01/1993 - "Pain is quantified by the patient on a numerical scale of 1 to 10 at 1.5-min intervals during Phase 1 and 9-min intervals during Phase 2. In simulation trials in which a fixed approximate model was used for the effect of sedation on pain while the pharmacokinetics of alfentanil were varied from one simulated patient to another, zero pain was achieved in under 15 min with minimal overshoot in plasma drug concentration and was maintained, with only minor deviation, by means of low drug concentrations." 04/01/2008 - "In contrast, in brain regions known to process the affective dimension of pain (parahippocampal gyrus, amygdala, anterior insula), pain-related activation disappeared at the lowest alfentanil dose, without genotype differences." 04/01/2008 - "In brain regions associated with the processing of the sensory intensity of pain (primary and secondary somatosensory cortices, posterior insular cortex), activation decreased linearly in relation to alfentanil concentrations, which was significantly less pronounced in OPRM1 118G carriers" 03/01/2007 - "OUTCOMES MEASUREMENT: Preprocedural anxiety, intraprocedural alfentanil consumption, visual analogue scale for pain" Order ALL the reference details at left...
2.	Postoperative Pain 10/01/1996 - "CONCLUSION: Compared to intravenous infusion of alfentanil epidural infusion resulting in the same plasma concentrations is not more effective in relieving postoperative pain" 10/01/1996 - "BACKGROUND: This study was designed to compare the efficacy of epidural vs. intravenous administration of alfentanil for treatment of postoperative pain" 06/01/1994 - "This study was designed to compare the efficacy and serum concentrations of alfentanil given subcutaneously (SQ) or epidurally (EPID) for treatment of postoperative pain" 10/01/2008 - "Patients in Groups LK and LDK required less alfentanyl for control of intraoperative and early postoperative pain" 08/01/1996 - "Alfentanil dose-response relationships for relief of postoperative pain." Order ALL the reference details at left...
3.	Vomiting 08/01/1993 - "Vomiting after alfentanil anesthesia." 10/01/1992 - "Vomiting after alfentanil anesthesia: effect of dosing method." 06/01/1990 - "The purpose of this study was to examine three anesthetic techniques utilizing alfentanil with regard to time to awakening, time to orientation and incidence of nausea and vomiting" 12/01/2000 - "Vomiting and nausea with alfentanil was noted in three patients" 03/01/1997 - "Variables measured were intraoperative alfentanil requirements, time until extubation, presence and intensity of pain in the immediate postoperative period and incidence of vomiting" Order ALL the reference details at left...
4.	Burns 11/01/1992 - "The volume of distribution and total clearance of alfentanil were reduced significantly in the burns group" 11/01/1992 - "Disposition of alfentanil in burns patients." 12/01/2000 - "Median (range) total dose of alfentanil was 2.6 (1-10.7) mg. This study supports the efficacy of an operator-adjusted target-controlled infusion of alfentanil to provide analgesia for burn dressing changes." 12/01/2000 - "This study aimed to determine whether an operator-adjusted target-controlled infusion of alfentanil could provide effective analgesia for burn dressing changes" 12/01/2000 - "The use of a target-controlled infusion of alfentanil to provide analgesia for burn dressing changes A dose finding study." Order ALL the reference details at left...
5.	Nausea 06/01/1990 - "The purpose of this study was to examine three anesthetic techniques utilizing alfentanil with regard to time to awakening, time to orientation and incidence of nausea and vomiting" 03/01/2005 - "One patient in group II had nausea and another one patient displayed hypoxemia after alfentanil administration" 12/01/2000 - "Vomiting and nausea with alfentanil was noted in three patients" 05/01/1996 - "One patient experienced nausea but no vomiting, no other adverse effects of alfentanil were noted" 10/01/1992 - "We conclude that alfentanil infusion for laparoscopic surgery entails a high risk for nausea and vomiting." Order ALL the reference details at left...

Related Drugs and Biologics

1.	Propofol (Diprivan)
2.	Fentanyl (Sublimaze)
3.	Ketamine
4.	remifentanil (Ultiva)
5.	Lidocaine (Xylocaine)
6.	Midazolam (Versed)
7.	Droperidol
8.	Methohexital (Brevital)
9.	Opioid Analgesics (Opioids)
10.	Nitrous Oxide (Laughing Gas)

Related Therapies and Procedures

1.	Anesthesia
2.	Patient-Controlled Analgesia (Analgesia, Patient Controlled)
3.	Analgesia
4.	Lithotripsy (Extracorporeal Shockwave Lithotripsy)
5.	Hysterectomy

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