|1.||Fichna, Jakub: 11 articles (11/2015 - 01/2012)|
|2.||Talley, Nicholas J: 11 articles (05/2009 - 05/2002)|
|3.||Chey, William D: 8 articles (11/2012 - 02/2005)|
|4.||Talley, N J: 8 articles (03/2010 - 09/2000)|
|5.||Sałaga, Maciej: 6 articles (10/2015 - 03/2014)|
|6.||Benninga, Marc A: 6 articles (04/2015 - 07/2006)|
|7.||McCallum, Richard W: 6 articles (01/2014 - 10/2005)|
|8.||Tack, J: 6 articles (01/2014 - 06/2006)|
|9.||Camilleri, M: 6 articles (06/2013 - 01/2000)|
|10.||Conwell, Darwin L: 6 articles (03/2013 - 01/2003)|
03/01/2014 - "Most linaclotide-treated IBS-C patients who were FDA non-responders reported some improvement in abdominal pain and stool frequency, and global relief/satisfaction. "
10/01/2013 - "Data from Phase II and III clinical trials demonstrated that linaclotide seems to produce a statistically significant increase in stool frequency, improved straining, decreased abdominal pain and discomfort."
01/01/2013 - "A significantly greater proportion of linaclotide-treated vs. placebo-treated patients were 12-week abdominal pain/discomfort responders (Trial 31: 54.8% vs. 41.8%; Trial 302: 54.1% vs. 38.5%; P < 0.001) and IBS degree-of-relief responders (Trial 31: 37.0% vs. 18.5%; Trial 302: 39.4% vs. 16.6%; P < 0.0001). "
12/01/2013 - "During 26 weeks of linaclotide administration, a significantly greater percentage of patients (70%) had at least a 30% reduction in abdominal pain compared with patients given placebo (50%). "
01/01/2013 - "Linaclotide treatment significantly improved abdominal pain/discomfort and degree-of-relief of IBS-C symptoms compared with placebo over 12 and 26 weeks. "
|2.||Anti-Bacterial Agents (Antibiotics)IBA
07/01/2014 - "After 2 years of follow-up, recurrences of nonoperatively treated right lower quadrant abdominal pain are less than 14% and may be safely and effectively treated with further antibiotics."
10/01/2015 - "Nine of 17 patients (52.9%) required inpatient hospitalization following ERCP; the most common indications were abdominal pain and need for IV antibiotics. "
06/01/2014 - "Use of antibiotics in infancy and childhood and risk of recurrent abdominal pain--a Swedish birth cohort study."
12/01/2013 - "Although conservative management with fasting and antibiotics ameliorated the abdominal pain, the mass remained approximately 5cm at its largest diameter. "
10/01/2013 - "Statements with 100% agreement and 'high' evidence levels indicated that: (i) specific probiotics help reduce overall symptom burden and abdominal pain in some IBS patients; (ii) in patients receiving antibiotics/Helicobacter pylori eradication therapy, specified probiotics are helpful as adjuvants to prevent/reduce the duration/intensity of AAD; (iii) probiotics have favourable safety in patients in primary care. "
|3.||Prednisolone (Predate)FDA LinkGeneric
07/01/2003 - "Although lamina propria T-lymphocyte counts decreased significantly after prednisolone (22.0% +/- 5.6%, P = 0.003), but not after placebo (11.5% +/- 8.6%, P = 0.1), this was not associated with any significant treatment-related improvement in abdominal pain, diarrhoea, frequency or urgency. "
03/01/2012 - "After the administration of oral prednisolone 40 mg daily for therapeutic trial, abdominal pain and endoscopic lesions were improved. "
02/01/2004 - "His abdominal pain and muscle involvement improved 1 week after commencing oral prednisolone therapy. "
10/01/1999 - "The patient improved with conservative treatment but complained of abdominal pain when the prednisolone (PSL) dose was decreased. "
06/01/2008 - "The patient was referred to our hospital because of severe abdominal pain that was unresponsive to prednisolone. "
08/01/1991 - "The study population included 133 consecutive patients with a chief complaint of abdominal pain who had amylase drawn over a 2-week period at a university hospital ED. "
01/28/2015 - "Generally, it is defined as the onset of new pancreatic-type abdominal pain severe enough to require hospital admission or prolonged hospital stay with levels of serum amylase two to three times greater than normal, occurring 24 h after ERCP. "
08/07/2013 - "During postprocedural follow-up, abdominal pain and elevated amylase levels were noted in three patients and one patient developed abdominal perforation. "
04/01/2013 - "A 7-year-old girl was referred to our hospital for severe abdominal pain and elevated serum levels of amylase and aminotransferase. "
01/01/2013 - "The main clinical features of this case were abdominal pain and increased levels of plasma amylase as well as liver function test. "
|5.||tegaserod (Zelnorm)FDA Link
01/01/2004 - "Tegaserod did not significantly improve the patients' individual symptoms of abdominal pain and discomfort although bowel habit showed a statistically significant improvement with tegaserod 4 mg and there was a non-significant trend in favour of tegaserod 12 mg. When GI symptoms were assessed separately, those indicative of GI motility such as number of bowel movements and days without bowel movements were generally improved with tegaserod although the proportion of patients experiencing diarrhoea was significantly higher in the tegaserod 12 mg group compared with placebo (RR 2.75, 95% CI 1.90, 3.97), with a number needed to harm (NNH) of 20. "
11/01/2004 - "Patients who were treated with tegaserod had an overall improvement in IBS symptoms (Subject's Assessment of Global Relief) as well as in secondary end points, such as abdominal pain and discomfort, stool consistency, change in bowel movements and relief of bloating. "
01/01/2004 - "Tegaserod has been assessed in a number of international multicentre trials and its use leads to an improvement in abdominal pain and bowel dysfunction as well as global well-being, at the expense of remarkably few adverse effects. "
04/01/2003 - "In clinical trials with tegaserod, the Subject's Global Assessment (SGA) of Relief (a global measure that includes overall wellbeing, abdominal pain/discomfort, and bowel function) was used to identify responders. "
01/01/2008 - "In the group with other indications to start tegaserod therapy, moderate or significant relief of abdominal pain and bloating was noted in 64% and 68% of patients, respectively. "
|6.||Opioid Analgesics (Opioids)IBA
01/01/2007 - "We hold that current evidence supports the administration of opioids to children with acute abdominal pain, and future trials will help determine safe and effective timing and dosing related to opioid administration."
01/01/2007 - "The review provide some evidence to support the notion that the use of opioid analgesics in patients with acute abdominal pain is helpful in terms of patient comfort and does not retard decisions to treat."
11/01/1999 - "Opioids relieved abdominal pain. "
02/01/2007 - "Randomized clinical trials (RTCs) comparing the use of opioid analgesics with placebo administered before any procedure in patients with acute nontraumatic abdominal pain were included. "
02/01/2007 - "The aim of the present study was to determine whether the use of opioid analgesics in patients with acute nontraumatic abdominal pain increases the risk of diagnostic error. "
|7.||Morphine (MS Contin)FDA LinkGeneric
01/20/2010 - "Abdominal pain was significantly relieved and the patients' cooperation was improved in the morphine group after 30 minutes treatment compared with the control group and before morphine administration (P<0.05). "
01/20/2010 - "Morphine relieved abdominal pain and improved the patients' cooperation for treatment and care. "
09/01/2010 - "This study involved 10 patients (5 male and 5 female) with cancerous abdominal pain, for whom the original opioid regimen was switched to morphine alone or continued in combination with morphine. "
01/01/2003 - "The study was a prospective, double-blind clinical trial in which adult Emergency Department (ED) patients with undifferentiated abdominal pain were randomized to receive placebo (control group, n = 36) or morphine sulphate (MS group, n = 38). "
11/01/1997 - "We conducted a randomized, prospective, placebo-controlled trial to investigate changes in physical examination following the administration of placebo, 5 mg, or 10 mg of morphine to 49 patients with acute abdominal pain. "
|8.||Misoprostol (Cytotec)FDA LinkGeneric
01/01/2011 - "After treating herself for a self-diagnosed pregnancy with illegally provided misoprostol, this patient presented with persistent lower abdominal pain. "
01/01/2011 - "A girl presented with constant lower abdominal pain after taking misoprostol for pregnancy termination. "
04/01/2008 - "Self-administered vaginal misoprostol of 1000 micrograms at home the evening before operative hysteroscopy is safe and highly acceptable, although a small proportion of women experienced severe lower abdominal pain. "
11/01/2005 - "Only 2 women (3.9%) experienced mild lower abdominal pain after misoprostol application. "
07/01/2004 - "Lower abdominal pain peaked at 1 and 2 hours after oral misoprostol, while it did so at 2 and 3 hours after vaginal misoprostol. "
05/01/2003 - "A trial of dietary lactose restriction may be beneficial in reducing abdominal pain in children with lactose maldigestion."
01/01/2013 - "The concurrent reduction in abdominal pain and improved overall tolerance could be a meaningful benefit to lactose intolerant individuals."
06/01/1981 - "This result compared with improvement occurring in five of 12 (42%) absorbers with recurrent abdominal pain who received a regular diet for one year and suggests that the elimination of lactose will not affect the overall frequency of improvement in recurrent abdominal pain. "
05/21/1994 - "A lactose-free diet was proposed and led to the disappearance of abdominal pain in 24% and a clear improvement in 32%. "
05/15/1985 - "Incomplete lactose absorption is a relatively benign condition that can be added to the differential diagnosis of gas-fluid levels in the colon and may account for some cases of spontaneous resolution of clinical and radiologic signs in children presenting with acute recurrent abdominal pain."
|10.||rifaximin (L 105)FDA Link
08/01/2011 - "In addition, more patients in the rifaximin group than in the placebo group (p < 0.001) reported an adequate relief of bloating, and an improvement in abdominal pain and stool consistency - secondary outcome measures. "
11/01/2013 - "We recorded one serious adverse event in a participant in the rifaximin group who had grade 3 right lower quadrant abdominal pain 72 h after the last intake of study drug. "
08/01/2011 - "In summary, a 2-week course of rifaximin provided significant relief of IBS symptoms, as well as bloating and abdominal pain."
01/06/2011 - "In addition, significantly more patients in the rifaximin group had a response to treatment as assessed by daily ratings of IBS symptoms, bloating, abdominal pain, and stool consistency. "
10/01/2009 - "Larger doses of rifaximin were statistically better for abdominal pain. "
01/01/2008 - "The minimum duration of therapy considered was one week, and studies had to report either a global assessment of cure or improvement in symptoms, or cure of or improvement in abdominal pain, after treatment. "
12/01/2011 - "The Rosemont classification system can identify patients who are more likely to have improvement in abdominal pain after treatment with pancreatic enzyme supplementation."
07/01/2008 - "The symptoms of hemafecia and abdominal pain were improved, the disease active index (DAI) was lowered after treatment in both groups (P <0.01), but the improvement of hemafecia, time of disappearance of mucous bloody stool and decrease of DAI in the treatment group were superior to those in the control group (P <0.05 or P <0.01). "
09/01/2014 - "The patient's chief complaints of right upper abdominal pain and abdominal fullness remarkably improved after treatment initiation. "
01/01/1983 - "Frequency, stool consistency, abdominal pain and signs of venous stasis improved after treatment. "
01/01/1989 - "The authors believe that elective cholecystectomy is to be recommended (emergency cholecystectomy is associated with a high morbidity) as the children operated were improved by surgery, with resolution of abdominal pain."
01/01/1998 - "Although more than one-third complained of abdominal pain after cholecystectomy, 93% had improved or were cured. "
10/01/2015 - "The aim of this study was to determine characteristics associated with patient-reported absence of abdominal pain after cholecystectomy, improved abdominal symptoms, and patient-reported positive cholecystectomy results in a prospective cohort multicentre study. "
01/01/2014 - "She refused cholecystectomy, and the abdominal pain gradually improved in response to conservative treatment. "
10/01/2011 - "Factors that predict relief from upper abdominal pain after cholecystectomy."
|3.||Drug Therapy (Chemotherapy)
01/01/2014 - ", one trial found that drug therapies that reduce gastric acidity improved gastro-intestinal symptoms such as abdominal pain; seven trials reported significant improvement in measures of fat malabsorption; and two trials reported no significant improvement in nutritional status. "
01/01/2012 - "However, one trial found that drug therapies that reduce gastric acidity improved gastro-intestinal symptoms such as abdominal pain; seven trials reported significant improvement in measures of fat malabsorption; and two trials reported no significant improvement in nutritional status. "
05/01/2008 - "The abdominal pain and appetite loss improved after the first course of chemotherapy, and therapeutic efficacy was rated PR. "
12/01/1994 - "A 43 year old woman in remission from acute myeloid leukaemia developed abdominal pain, severe melaena, diarrhoea and gram-negative septicaemia whilst severely pancytopenic following consolidation chemotherapy. "
08/01/1991 - "Chest X ray findings improved after 4 months' antituberculous chemotherapy, but he complained of right lower abdominal pain and a mass with tenderness. "
01/01/2004 - "The author suggests that the ROME II criteria for FFR could be improved by including the following additional items: a history of BMs that obstruct the toilet, a history of chronic abdominal pain relieved by enemas or laxatives, and the presence of an abdominal fecal mass or rectal fecal mass."
01/01/2015 - " trial reported none of the following pre-specified secondary outcomes: stool consistency using Bristol stool form scale , use of alternative products , laxative agents , enemas , relief of abdominal pain/discomfort and stool frequency . "
02/01/2013 - "A 61-year-old man and a 45-year-old man presented with abdominal pain after forceful entry of tap water into the rectum, during rinsing of the anus after defecation in the first case, and during self-administered enema in the second case. "
11/01/2005 - "The patient developed abdominal pain approximately 3.5 h after a pre-procedural enema was administered. "
07/01/2004 - "The RS procedure provided excellent continence control, with a shortening of the enema duration, a lower fluid volume, and good cosmesis, and without any ACE-related abdominal pain. "
09/01/2005 - "The therapeutic value of elective laparoscopic appendectomy in the management of chronic abdominal pain."
09/01/2014 - "Efficacy of preoperative computed tomography imaging to reduce negative appendectomies in patients undergoing surgery for left lower quadrant abdominal pain."
06/01/1999 - "Three patients had undergone previous diagnostic explorations for abdominal pain, the appendix was not removed, and a subsequent appendectomy relieved the discomfort. "
01/01/1998 - "Sonographic diagnosis of right sided abdominal pain helped to reduce the risk of restricted indication for diagnostic laparoscopy respectively appendectomy by reducing the number of unnecessary operations without relevant change of perforation rate."
11/01/1980 - "Ninety-six per cent of these 70 children had been relieved of their recurrent abdominal pain by appendectomy. "