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Calcitonin Gene-Related Peptide

Calcitonin gene-related peptide. A 37-amino acid peptide derived from the calcitonin gene. It occurs as a result of alternative processing of mRNA from the calcitonin gene. The neuropeptide is widely distributed in neural tissue of the brain, gut, perivascular nerves, and other tissue. The peptide produces multiple biological effects and has both circulatory and neurotransmitter modes of action. In particular, it is a potent endogenous vasodilator.
Also Known As:
Calcitonin Gene-Related Peptide I; Calcitonin Gene-Related Peptide II; alpha-CGRP; beta-CGRP; Calcitonin Gene Related Peptide; Calcitonin Gene Related Peptide I; Calcitonin Gene Related Peptide II; Gene-Related Peptide, Calcitonin; Peptide, Calcitonin Gene-Related; alpha CGRP; beta CGRP
Networked: 1883 relevant articles (44 outcomes, 233 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Edvinsson, Lars: 27 articles (01/2016 - 01/2002)
2. Ohtori, Seiji: 26 articles (12/2015 - 09/2003)
3. Takahashi, Kazuhisa: 25 articles (12/2015 - 04/2004)
4. Goadsby, Peter J: 20 articles (10/2015 - 11/2002)
5. Russo, Andrew F: 18 articles (06/2015 - 04/2002)
6. Aoki, Yasuchika: 17 articles (10/2015 - 04/2004)
7. Inoue, Gen: 17 articles (10/2015 - 10/2006)
8. Li, Yuan-Jian: 17 articles (03/2013 - 05/2002)
9. Orita, Sumihisa: 16 articles (10/2015 - 10/2009)
10. Olesen, J: 16 articles (01/2012 - 05/2000)

Related Diseases

1. Migraine Disorders (Migraine)
2. Headache (Headaches)
3. Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage)
4. Heart Failure
5. Ischemia

Related Drugs and Biologics

1. Calcitonin Gene-Related Peptide Receptors (Calcitonin-Gene Related Peptide Receptor)
2. Substance P
3. N- (6- (2,3- difluorophenyl)- 2- oxo- 1- (2,2,2- trifluoroethyl)azepan- 3- yl)- 4- (2- oxo- 2,3- dihydro- 1H- imidazo(4,5- b)pyridin- 1- yl)piperidine- 1- carboxamide
4. Neuropeptides
5. Vasoactive Intestinal Peptide (VIP (Vasoactive Intestinal Peptide))
6. calcitonin gene-related peptide (8-37)
7. Vasodilator Agents (Vasodilators)
8. olcegepant
9. Neuropeptide Y
10. Capsaicin (Zostrix)

Related Therapies and Procedures

1. Denervation
2. Radiotherapy
3. Aftercare (After-Treatment)
4. Anesthesia
5. Axotomy