|1.||Li, Ping: 2 articles (10/2014 - 01/2011)|
|2.||Jin, Xiaodong: 2 articles (10/2014 - 01/2011)|
|3.||Li, Qiang: 2 articles (10/2014 - 01/2011)|
|4.||Zhou, Libin: 2 articles (10/2014 - 01/2011)|
|5.||Liu, Xinguo: 2 articles (10/2014 - 01/2011)|
|6.||Choi, Hye Joung: 2 articles (02/2014 - 01/2011)|
|7.||Zhu, Bao Ting: 2 articles (02/2014 - 01/2011)|
|8.||Attia, Sabry M: 2 articles (06/2013 - 03/2008)|
|9.||Poon, Randy Y C: 2 articles (06/2012 - 08/2006)|
|10.||Samuel, Temesgen: 2 articles (01/2010 - 01/2005)|
01/01/2011 - "To understand how human tumor cells respond to the combined treatment with nocodazole and high LET radiation, alterations in cell cycle, mitotic disturbances and cell death were investigated in the present study. "
12/26/2013 - "Moreover, nocodazole, an antimicrotubule drug, potently induces LATS2 to suppress tumor growth in vivo by targeting β-catenin/BCL9. "
11/06/2009 - "Interestingly, nocodazole (NCZ), which induces G2/M block, increased the percentage of senescent cells as well as the expression of miR-290 and of the tumor suppressor p16, thus mimicking culture senescence. "
12/01/2007 - "CCT120202-treated human tumor cells showed a delay in mitosis, abrogation of nocodazole-induced mitotic arrest, and spindle defects. "
01/01/2004 - "Transfection of CHFR in one of these cancer cell lines lowered the mitotic index after nocodazole treatment. "
08/01/2004 - "In addition, ASFV infection resulted in the increased acetylation of microtubules as well as their protection against depolymerization by nocodazole. "
11/13/2013 - "Although the MT depolymerizing agent nocodazole affected dynamic MTs, HIV-1 particles localized to nocodazole-resistant stable MTs, and infection was minimally affected. "
12/01/2012 - "Treatment of BEFV-infected cells with nocodazole significantly decreased the M protein synthesis and viral yield, indicating that microtubules play an important role in BEFV productive infection, likely by mediating trafficking of BEFV-containing endosomes. "
05/01/2009 - "These results demonstrate that a single dose of nocodazole delays, but does not block, WNV infection of the brain."
05/01/2009 - "C57BL/6J mice were treated with nocodazole, a microtubule inhibitor that blocks ART, prior to infection with WNV. "
08/25/1993 - "To examine the role of microtubules in TfR traffic, K562 cultured human leukemia cells treated with nocodazole to depolymerize microtubules were studied. "
03/01/1983 - "Chemotherapeutic efficacy of Nocodazole encapsulated in liposomes on L1210 murine leukemia."
03/01/2009 - "In this study, we used models of aphidicolin and nocodazole-synchronized HL-60 and NB4 leukemia cell lines to determine the kinetics of ERK activity during the progression of the cell cycle and to test the effects of commercially available inhibitors on G(2)/M progression of synchronized leukemia cells. "
02/01/1989 - "In an attempt to identify a soluble oncodazole analogue that could be easily formulated, a series of substituted oncodazoles was synthesized and evaluated for tubulin binding affinity, in vitro cytotoxicity against cultured mouse B-16 cells, and ability to prolong lifespan at the maximally tolerated dose in the P388 mouse leukemia model. "
03/01/1983 - "The present data indicate that enclosing Nocodazole, a water insoluble antimitotic compound, in liposomes results in an enhanced therapeutic activity against L1210 murine leukemia."
08/01/2014 - "Nocodazole-treated oocytes did not display increased DNA damage signals that were marked by γH2A.X signal strength, but reformed spindles and underwent maturation, although aneuploidy increased after extended nocodazole treatment. "
12/15/2009 - "Nocodazole-mediated aneuploidy was increased in p53-defective (p53Mut) cells; however, it was not increased in p53 wild-type (p53WT) cells. "
05/08/2008 - "The depletion of HSF1 from cells highly expressing HSF1 reduced nocodazole-mediated aneuploidy in cells. "
06/22/2006 - "A549, aneuploid cell line, aberrantly passed through the mitotic phase and became multinuclei morphology in the presence of nocodazole. "
10/15/2005 - "Overexpression of mutant Mad2 in HeLa cells led to the appearance of aneuploid cells in the presence of nocodazole, and this indicated that these mutations caused a defect in MAD2 protein. "
|5.||Breast Neoplasms (Breast Cancer)
06/01/2012 - "Nocodazole in a dose of 100 ng/ml was used to induce polyploidization in a breast cancer cell line MDA-MB-231 cells. "
01/15/2007 - "Microinjection of the ANK peptide in breast cancer cell line overexpressing SNCG (MCF7-SNCG) exhibited a similar cell killing response by nocodazole as in the SNCG-negative MCF7 cells. "
01/01/2004 - "In conclusion, our data suggested that low CHFR expression associated with high mitotic indices in response to nocodazole treatment were common in the breast cancer cell lines studied. "
10/23/2003 - "Accompanied with a reduction of BubR1 protein level, BCSG1 expression resulted in multinucleation of breast cancer cells upon treatment with spindle inhibitor nocodazole, indicating an impaired mitotic checkpoint. "
07/01/2002 - "After treatment with 1 microM nocodazole, seven of ten breast cancer lines (type A cells) arrested in mitosis, whereas the other three (type B cells) did not. "
|7.||Proteins (Proteins, Gene)
|2.||Heterologous Transplantation (Xenotransplantation)
|4.||Drug Therapy (Chemotherapy)