A progestational and glucocorticoid hormone antagonist. Its inhibition of progesterone induces bleeding during the luteal phase and in early pregnancy by releasing endogenous prostaglandins from the endometrium or decidua. As a glucocorticoid receptor antagonist, the drug has been used to treat hypercortisolism in patients with nonpituitary CUSHING SYNDROME.
Also Known As:
RU 486; Mifeprex; RU-486; RU486; Mifegyne; Mifégyne; R-38486; R38486; RU-38486; ZK-98296; ZK98296; R 38486; RU 38486; RU38486; ZK 98296; Estra-4,9-dien-3-one, 11-(4-(dimethylamino)phenyl)-17-hydroxy-17-(1-propynyl)-, (11beta,17beta)-