|1.||Schiffer, Celia A: 2 articles (08/2003 - 03/2002)|
|2.||Hongpo, W: 1 article (01/2014)|
|3.||Ji, W Q: 1 article (01/2014)|
|4.||Hong, Z: 1 article (01/2014)|
|5.||Alam, M A: 1 article (01/2014)|
|6.||Wang, Yong: 1 article (12/2013)|
|7.||Woster, Patrick M: 1 article (12/2013)|
|8.||Liu, Zhigang: 1 article (12/2013)|
|9.||Kovari, Ladislau C: 1 article (12/2013)|
|10.||Kovari, Iulia A: 1 article (12/2013)|
01/01/1989 - "Because of the very close relationship of their predicted gag and pol gene products and similarities in clinical manifestations of the disease, EIA served as a model to study immunological events involved in the host defence against lymphocytotropic viral infections. "
04/01/2009 - "Compared with HSV-1 lytic infection, the recombinant Pol protein exhibited a reduced stability with a half-life of 7 h. "
06/15/2004 - "Diagnosis of HIV-1 infection: importance of taking into account the anti-pol gene product reactivity in the interpretation of Western blot results."
01/01/2003 - "The most well-known proteolytic action in the retroviral life-cycle is the processing of the Gag and Gag-Pro-Pol polyproteins with the virally encoded protease at the late phase of viral infection. "
02/15/1995 - "Retroviral proteinase(PR)-catalyzed cleavage of the viral Gag and Gag-Pol polyproteins within the nascent virus particle is required for productive viral infection. "
|2.||Weight Loss (Weight Reduction)
|4.||Contagious Ecthyma (Orf)
01/01/2005 - "Diaspora is 11,737 bp in length and contains a single 1892-codon ORF that encodes a gag-pol polyprotein. "
08/11/1997 - "The polypeptide encoded by the burdock ORF contains two adjacent regions homologous to the gag and pol polyproteins of the gypsy mobile element. "
08/01/1996 - "This longer ORF was shown to be capable of encoding a beta-pol protein, larger than wild-type beta-pol, that cross-reacted with beta-pol antibody and exhibited beta-pol enzymatic activity. "
01/01/2005 - "A hepatitis B virus (HBV)-derived sequence that encodes the 832-residue polymerase (Pol) protein of HBV in the primary open reading frame (ORF), and the three (large, middle and small) hepatitis B surface antigen (HBsAg) variants in an alternative ORF was used. "
01/01/1999 - "A sequenced SIRE-1 genomic copy has an uninterrupted ORF that can be translated into a gag-pol polyprotein, followed by an unprecedented second ORF whose conceptual translation yielded a theoretical protein predicted to possess many of the same secondary structural elements found in mammalian retroviral envelope proteins. "
|5.||Acquired Immunodeficiency Syndrome (AIDS)
09/26/1985 - "We demonstrate a much closer relationship of their predicted pol gene products to that of the presumed aetiological agent of human acquired immune deficiency syndrome (AIDS) than to those of other retroviruses. "
01/01/2010 - "The viral Gag and Gag-Pro-Pol polyproteins are processed by the retroviral protease in the last stage of replication and inhibitors of the HIV-1 protease are widely used in AIDS therapy. "
08/01/2003 - "HIV-1 protease is a major drug target against AIDS as it permits viral maturation by processing the gag and pol polyproteins of the virus. "
03/01/2002 - "The homodimeric HIV-1 protease is the target of some of the most effective antiviral AIDS therapy, as it facilitates viral maturation by cleaving ten asymmetric and nonhomologous sequences in the Gag and Pol polyproteins. "
|1.||RNA-Directed DNA Polymerase (Reverse Transcriptase)
|2.||Human immunodeficiency virus 1 p16 protease
|4.||env Gene Products
|5.||gag Gene Products (gag Protein)
|7.||Messenger RNA (mRNA)
|8.||Proteins (Proteins, Gene)
|9.||DNA (Deoxyribonucleic Acid)