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Tylosin

Macrolide antibiotic obtained from cultures of Streptomyces fradiae. The drug is effective against many microorganisms in animals but not in humans.
Also Known As:
Fradizine; Tylan; Tylosin Hydrochloride; Tylosin Tartrate; Tylosin Tartrate (Salt); Tylosine; Hydrochloride, Tylosin; Tartrate, Tylosin
Networked: 206 relevant articles (29 outcomes, 35 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Westermarck, Elias: 5 articles (08/2014 - 03/2005)
2. Nagaraja, T G: 4 articles (04/2021 - 07/2007)
3. Belk, Keith E: 3 articles (01/2022 - 11/2017)
4. Morley, Paul S: 3 articles (01/2022 - 11/2017)
5. Amachawadi, Raghavendra G: 3 articles (04/2021 - 06/2018)
6. Zaheer, Rahat: 3 articles (01/2020 - 01/2013)
7. Schwarz, Stefan: 3 articles (10/2016 - 01/2007)
8. Spillmann, Thomas: 3 articles (08/2014 - 10/2009)
9. Skrzypczak, Teresa: 3 articles (04/2011 - 03/2005)
10. Gaspari, Anthony A: 2 articles (05/2021 - 01/2021)

Related Diseases

1. Infections
2. Diarrhea
3. Liver Abscess
4. Weight Gain
5. Body Weight (Weight, Body)
04/01/1986 - "Tylosin at 44 mg/kg changed to 22 mg/kg at 57 kg body weight caused an increase (P = .07) in rate of gain for the overall grower-finisher period and an improvement in feed efficiency in the grower (P = .07) and the grower-finisher (P less than .05) periods. "
10/01/2001 - "Tylosin at all levels provided improvement in Day 29 body weight, average daily gain, feed to gain ratio, and average daily feed intake compared to unmedicated birds. "
10/01/1982 - "In the 1st phase of this study, tylosin was administered IM to quail, pigeons, and emus at a dosage rate of 25 mg/kg of body weight and to cranes at a dosage rate of 15 mg/kg. The average peak plasma concentrations of tylosin in quail, pigeons, cranes, and emus were 4.31, 5.63, 3.62, and 3.26 microgram/ml, respectively. "
02/01/1977 - "Data generated through 17 clinical cases indicated that the minimum inhibitory concentration for tylosin in Pasteurella spp tested was about 6.25 mcs/ml and for hemolytic Staphylococcus spp tested greater than or equal to 0.4 mug/ml. Thus, it would appear that tylosin, given at the recommended dose (6.6 to 11.0 mg tylosin activity/kg of body weight once or twice per day), would produce serum levels insufficient to treat all Pasteurella spp and some hemolytic Staphylococcus spp tested since a serum level of tylosin at slightly higher than 1 mug/ml for about 30 minutes was achieved in this study."
01/01/2022 - "After one week of challenge, the broilers that received tylosin had a higher body weight gain (BWG) than those in the control group (p < 0.05), while the other treatments presented intermediate values. "

Related Drugs and Biologics

1. Anti-Bacterial Agents (Antibiotics)
2. Phosphates (Orthophosphate)
3. Chlortetracycline (Aureomycin)
4. Tablets
5. Macrolides
6. Oxytetracycline (Terramycin)
7. danofloxacin
8. tilmicosin
9. Lincomycin (Lincocin)
10. Erythromycin (Erycette)

Related Therapies and Procedures

1. Therapeutics
2. Injections
3. Intravenous Administration
4. Intramuscular Injections
5. Drug Therapy (Chemotherapy)