Tissue Expansion

A procedure whereby the body is stimulated to generate extra soft tissue by the application of stretching forces that stimulate new growth of tissue which, over a period of time, results in a 2-dimensional expansion of the tissue. The procedure is used in reconstructive surgery for injuries caused by trauma, burns, or ablative surgery. Various types of TISSUE EXPANSION DEVICES have been developed that exert stretching forces.

Also Known As:

Networked: 633 relevant articles (20 outcomes, 37 trials/studies)

Relationship Network

Therapy Context: Research Results

Experts

1.	Gosain, Arun K: 6 articles (01/2018 - 11/2003)
2.	Pan, Bo: 3 articles (01/2022 - 01/2011)
3.	Sasaoka, Toshiyasu: 3 articles (11/2020 - 01/2019)
4.	Tsuneki, Hiroshi: 3 articles (11/2020 - 01/2019)
5.	Wada, Tsutomu: 3 articles (11/2020 - 01/2019)
6.	Wang, Xiaojun: 3 articles (08/2020 - 02/2013)
7.	Margulis, Alexander: 3 articles (02/2017 - 07/2004)
8.	Kuhl, Ellen: 3 articles (01/2017 - 10/2011)
9.	Driscoll, Daniel N: 3 articles (07/2016 - 02/2010)
10.	Fan, Jincai: 3 articles (01/2015 - 08/2004)

Related Diseases

1.	Wounds and Injuries (Trauma) 08/01/2011 - "Using a simple, inexpensive and non-invasive method of pre-operative tissue expansion results in a significant reduction in the costs of wound care for both in-hospital and out-of-hospital treatment. " 11/01/1992 - "Our data showed statistically significant reduction in the force required to close a wound after acute intraoperative tissue expansion when compared with baseline. " 09/01/2014 - "Invited Commentary: External tissue expansion and tension relief systems for improved utilisation of the viscoelastic properties of the skin in wound closure." 01/01/2015 - "To study and discuss role of external tissue expansion and wound closure (ETEWC) technique using hooks and rubber bands. " 11/01/2000 - "The results of the current study show that the technique of soft tissue expansion before total knee arthroplasty in patients at high risk for wound healing problems can successfully prevent catastrophic wound complications after the arthroplasty procedure and can avoid the need for disfiguring soft tissue reconstructions."
2.	Alopecia (Baldness) 07/01/1987 - "Male pattern baldness may be effectively eliminated in most patients through the use of soft-tissue expansion. " 07/01/1987 - "It is the combination of techniques, especially tissue expansion and punch-graft transplantation, that seems to hold the greatest promise for surgical treatment of baldness. " 02/01/2018 - "This study included 32 different children who underwent tissue expansions in the management of postburn alopecia. " 12/01/2021 - "Our results revealed that the ideal and cosmetic results can be obtained by flexible using of local flap modification, single FUE method, and FUE ectopic hair transplantation to repair the dissatisfied postoperative outcomes of temporal and sideburn cicatricial alopecia after tissue expansion." 12/01/2021 - "Corrective strategies for poor appearance after tissue expansion for temporal and sideburn cicatricial alopecia."
3.	Infections 03/01/2020 - "Once the soft-tissue envelope was restored and infection cleared, a full-thickness rotational flap with tissue expansion was performed. " 10/01/2019 - "The purpose of this study was to determine the economic impact of the reduced infection rate observed with the AeroForm tissue expander as compared with saline tissue expansion. " 11/01/2013 - "The goal of this study was to identify risk factors for infection during tissue expansion in TE/I breast reconstruction and to develop a simple risk scoring tool for infection that can be used for clinical application. " 11/01/2013 - "However, few studies have investigated the risk factors for infection during tissue expansion following TE/I breast reconstruction. " 04/20/2022 - "One patient had the expander exposed due to infection after the expander being inserted, while the other patients had no complications of skin and soft tissue expansion. "
4.	Nevus (Nevi) 12/01/1988 - "Giant nevi of the trunk were treated using a combination of abdominoplasty technique, tissue expansion, and split-thickness skin graft, with early "large segment" excision and grafting being the most effective treatment of giant nevi covering the posterior trunk. " 10/01/2023 - "All patients receive tissue expansion, nevus resection, expanded skin flap transfer, and pedicle division. " 01/01/2019 - "Multiple stage tissue expansion for reconstruction of scalp nevocellular nevus in pediatric age group." 01/01/2015 - "Large congenital nevus scalp managed by tissue expansion- a case report." 02/01/2012 - "The patient underwent eight operations and a total of 11 rounds of tissue expansions (500 cc × 9 rounds, 600 cc × 1 round, 300 cc × 1 round) were completed over a 2-year period prior to the removal of the nevus. "
5.	Burns 02/01/2014 - "Tissue expansion in the pediatric burn population continues to be a safe and effective reconstructive option with acceptable complication rates." 02/01/2014 - "This study is a 10-year follow-up to our previous publication reviewing the complication rates of tissue expansion in the pediatric burn population. " 12/01/2011 - "This study included 62 tissue expansions in 37 burn patients from January 2001 to June 2009. " 01/01/2021 - "The current literature focuses largely on tissue expansion for breast reconstruction and in the context of burn and pediatric skin/soft tissue replacement; however, less traditional applications are also prevalent. " 04/01/2020 - "Tissue expansion in child's burn sequelae is ideal in scalp, good in neck, chest and proximal upper limb, and to do carefully in lower limb and face."

Related Drugs and Biologics

1.	Intercellular Signaling Peptides and Proteins (Growth Factors)
2.	Cytokines
3.	Fluorouracil (Carac)
4.	Cyclophosphamide (Cytoxan)
5.	Bevacizumab (Avastin)
6.	Plastics
7.	Lidocaine (Xylocaine)
8.	Hydrogels
9.	Type A Botulinum Toxins (Botox)
10.	Analgesics (Analgesic Drugs)

Related Therapies and Procedures

1.	Transplantation
2.	Abdominoplasty
3.	Mammaplasty (Breast Reconstruction)
4.	Tissue Expansion Devices (Tissue Expander)
5.	Mastectomy (Mammectomy)