Optic Disk Drusen (Optic Disc Drusen)

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37 relevant articles (0 outcomes, 0 trials/studies) found for this Disease

Description: Optic disk bodies composed primarily of acid mucopolysaccharides that may produce pseudopapilledema (elevation of the optic disk without associated INTRACRANIAL HYPERTENSION) and visual field deficits. Drusen may also occur in the retina (see RETINAL DRUSEN). (Miller et al., Clinical Neuro-Ophthalmology, 4th ed, p355)

Also Known As:

Optic Disc Drusen; Drusen, Optic Disc; Optic Disc Drusens; Optic Disk Drusens; Optic Nerve Drusen; Drusen, Optic Disk; Drusen, Optic Nerve

Disease Context: Research Results

Nervous System Diseases: 3414

Cranial Nerve Diseases: 147

Optic Nerve Diseases: 876

Optic Disk Drusen: 37

Eye Diseases: 1244

Optic Nerve Diseases: 876

Optic Disk Drusen: 37

Related Diseases

1.	Hemorrhage
2.	Choroidal Neovascularization
3.	Optic Nerve Diseases (Optic Neuropathy)
4.	Angioid Streaks
5.	Retinoschisis (Retinoschisis, Juvenile)

Experts

1.	Pomeranz, Howard D: 1 article (02/2006)
2.	Katz, Bradley J: 1 article (02/2006)
3.	Lavaque, Alejandro J: 1 article (01/2005)
4.	Shah, Anish: 1 article (01/2005)
5.	Liggett, Peter E: 1 article (01/2005)
6.	Chaudhry, Nauman A: 1 article (01/2005)
7.	de Abreu, J Rui Faria: 1 article (09/2004)
8.	Silva, R: 1 article (09/2004)
9.	Travassos, A: 1 article (09/2004)
10.	Loureiro, R: 1 article (09/2004)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Optic Disk Drusen:

1.	Retinaldehyde (Retinal)IBA 06/01/2008 - "BACKGROUND: New technology allows more precise definition of structural alterations of all retinal layers although it has not been used previously in cases of optic disc drusen" 02/01/2006 - "PURPOSE: To evaluate the visual field with the use of automated perimetry and to evaluate the retinal nerve fiber layer (RNFL) with optical coherence tomography (OCT) in patients with buried optic nerve drusen (OND)" 02/01/2006 - "Visual field defects and retinal nerve fiber layer defects in eyes with buried optic nerve drusen." 07/01/2005 - "Peau d'orange was noted in 18 patients, optic nerve drusen in 5, and retinal crystalline bodies in 9. Choroidal neovascular membrane was present in 15 patients" 09/01/2000 - "CONCLUSION: Retinal nerve fiber layer myelination can occur spontaneously in adolescence, progress in adolescence, and be associated with optic nerve drusen." Order ALL the reference details at left...
2.	Fluorescein (Funduscein)FDA Link 01/01/2004 - "B-scan sonography, fluorescein angiography and computed tomography are the best imaging procedures for diagnosing of the optic disc drusen" 10/01/2003 - "Orbital computerized tomography(CT), B-scan echography and photography with a fluorescein angiography filter identified the granular lesions as optic nerve drusen" 01/01/1995 - "We performed computed tomography (CT), magnetic resonance imaging (MRI), fundus fluorescein angiography and B-mode ultrasonography (B-USG) on four patients with optic disc drusen as the sole identifiable pathological process" 06/01/1990 - "Perimetry, echography and fluorescein fundus angiography revealed optic disc drusen." 12/01/1982 - "As part of an examination of 180 patients with optic disc drusen, autofluorescence pictures had been taken in 116 patients and fluorescein angiograms in 67 patients" Order ALL the reference details at left...
3.	verteporfin (Visudyne)FDA Link 01/01/2005 - "Photodynamic therapy with verteporfin may be a useful treatment option in patients with choroidal neovascular membranes secondary to optic nerve drusen." 01/01/2005 - "The authors describe the use of photodynamic therapy with verteporfin for subfoveal choroidal neovascular membrane secondary to optic nerve drusen" 09/01/2004 - "Bilateral CNV associated with optic nerve drusen treated with photodynamic therapy with verteporfin." 09/01/2004 - "PURPOSE: To report a case of bilateral choroidal neovascularization (CNV) associated with optic nerve drusen (OND) treated with photodynamic therapy (PDT) with verteporfin" Order ALL the reference details at left...
4.	Melanins (Melanin)IBA 07/01/1984 - "The patient had small globes, bilateral posterior subcapsular cataracts, lacy vacuolation of the iris, ciliary process hyalinisation, unilateral asteroid hyalosis, total absence of rods and cones, intraretinal melanin pigment, retinal pigment epithelium atrophy, focal chorioretinal fusion, preretinal fibrosis, bilateral giant optic disc drusen, and optic nerve atrophy" Order ALL the reference details at left...
5.	Iron (Serum Iron Level)IBA 04/01/1975 - "All optic disc drusen were calcified and five of the ten disc drusen stained positively for the presence of iron." Order ALL the reference details at left...
6.	Insulin (Novolin)FDA Link 09/01/2006 - "PURPOSE: To report an insulin-dependent diabetic patient who was referred by the diabetic screening clinic as having proliferative diabetic retinopathy who was found to have bilateral optic disc drusen with optociliary shunt resembling neovascularization on the disc" Order ALL the reference details at left...
7.	HeliumIBA 10/01/2003 - "The optic nerve drusen could be seen more clearly by infrared laser than by helium-neon laser" Order ALL the reference details at left...
8.	ElastinIBA 01/01/2007 - "The starting point seems to be the accumulation of polyanions in the elastin of the cribriform plate, followed by disruption of axonal transport, mitochondrial extrusion and subsequent formation of optic disc drusen." Order ALL the reference details at left...
9.	Carbon MonoxideIBA 01/01/1975 - "A cilioretinal artery was observed to co-exist with optic disc drusen with a high frequency, i.e" Order ALL the reference details at left...
10.	Blood Proteins (Serum Proteins)IBA 03/01/1977 - "We believe that the tendency to develop optic nerve drusen results, at least in part, from a congenitally abnormal disc vasculature that allows transudation of plasma proteins that in turn serve as a nidus for the deposition of extracellular materials." Order ALL the reference details at left...

Therapies and Procedures

1.	Lasers (Laser) 03/01/1992 - "We examined four patients with the suspected diagnosis of optic disc drusen by scanning laser ophthalmoscopy (SLO) and fundus photography" 04/01/2004 - "CONCLUSION: Early diagnosis and immediate laser photocoagulation of vision-threatening choroidal neovascular membranes associated with optic disc drusen helps stop progression towards the macula and improves longterm visual acuity." 04/01/2004 - "Laser photocoagulation for choroidal neovascular membrane associated with optic disc drusen." 01/01/2000 - "Laser photocoagulation for choroidal neovascularization developed in a patient with optic disc drusen and angioid streaks]" 10/01/2003 - "The optic nerve drusen could be seen more clearly by infrared laser than by helium-neon laser" Order ALL the reference details at left...
2.	Light Coagulation 04/01/2004 - "CONCLUSION: Early diagnosis and immediate laser photocoagulation of vision-threatening choroidal neovascular membranes associated with optic disc drusen helps stop progression towards the macula and improves longterm visual acuity." 04/01/2004 - "Laser photocoagulation for choroidal neovascular membrane associated with optic disc drusen." 07/01/1981 - "Thus, despite potential submacular hemorrhage, we do not recommend routine photocoagulation for peripapillary choroidal neovascular membranes secondary to optic disk drusen." 01/01/2000 - "Laser photocoagulation for choroidal neovascularization developed in a patient with optic disc drusen and angioid streaks]" 04/01/2004 - "PURPOSE: To report two cases of choroidal neovascular membrane associated with optic disc drusen which were successfully treated using argon laser photocoagulation" Order ALL the reference details at left...
3.	Photochemotherapy (Photodynamic Therapy) 01/01/2005 - "Photodynamic therapy for choroidal neovascular membrane secondary to optic nerve drusen." 01/01/2005 - "Photodynamic therapy with verteporfin may be a useful treatment option in patients with choroidal neovascular membranes secondary to optic nerve drusen." 01/01/2005 - "The authors describe the use of photodynamic therapy with verteporfin for subfoveal choroidal neovascular membrane secondary to optic nerve drusen" 09/01/2004 - "Bilateral CNV associated with optic nerve drusen treated with photodynamic therapy with verteporfin." 09/01/2004 - "PURPOSE: To report a case of bilateral choroidal neovascularization (CNV) associated with optic nerve drusen (OND) treated with photodynamic therapy (PDT) with verteporfin" Order ALL the reference details at left...
4.	Laser In Situ Keratomileusis (LASIK) 09/01/2001 - "LASIK and optic nerve drusen." Order ALL the reference details at left...
5.	Vitrectomy 10/01/2004 - "METHODS: A retrospective study was carried out on four eyes (four patients) undergoing vitrectomy, retinotomy, and removal of CNV associated with optic disk drusen" Order ALL the reference details at left...

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