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AIDS Dementia Complex

A neurologic condition associated with the ACQUIRED IMMUNODEFICIENCY SYNDROME and characterized by impaired concentration and memory, slowness of hand movements, ATAXIA, incontinence, apathy, and gait difficulties associated with HIV-1 viral infection of the central nervous system. Pathologic examination of the brain reveals white matter rarefaction, perivascular infiltrates of lymphocytes, foamy macrophages, and multinucleated giant cells. (From Adams et al., Principles of Neurology, 6th ed, pp760-1; N Engl J Med, 1995 Apr 6;332(14):934-40)
Also Known As:
AIDS-Related Dementia Complex; Acquired-Immune Deficiency Syndrome Dementia Complex; Dementia Complex, Acquired Immune Deficiency Syndrome; Encephalopathy, AIDS; Encephalopathy, HIV; HIV-1 Cognitive and Motor Complex; AIDS Encephalopathies; AIDS Related Dementia Complex; Complex, AIDS Dementia; Complex, AIDS-Related Dementia; Dementia Complex, AIDS; Dementia Complex, AIDS Related; Dementia, HIV; Dementias, HIV; Encephalopathies, AIDS; Encephalopathies, HIV; HIV 1 Associated Cognitive Motor Complex; HIV 1 Cognitive and Motor Complex; HIV Associated Cognitive Motor Complex; HIV Dementias; HIV Encephalopathies; AIDS Encephalopathy; Dementia Complex, AIDS-Related; HIV Dementia; HIV Encephalopathy; HIV-1-Associated Cognitive Motor Complex; HIV-Associated Cognitive Motor Complex
Networked: 387 relevant articles (25 outcomes, 36 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Acquired Immunodeficiency Syndrome (AIDS)
2. Infection
3. Parkinson Disease (Parkinson's Disease)
4. Opportunistic Infections (Opportunistic Infection)
5. Dementia (Dementias)

Experts

1. Nath, Avindra: 17 articles (12/2013 - 06/2003)
2. Brew, Bruce J: 12 articles (01/2010 - 01/2003)
3. Price, Richard W: 10 articles (01/2010 - 10/2002)
4. Schifitto, Giovanni: 8 articles (01/2013 - 04/2002)
5. Nath, A: 8 articles (05/2008 - 06/2000)
6. Sacktor, Ned: 7 articles (02/2008 - 04/2002)
7. Hagberg, Lars: 6 articles (01/2010 - 05/2004)
8. Chang, Linda: 5 articles (09/2011 - 06/2003)
9. Cinque, Paola: 5 articles (01/2010 - 05/2004)
10. Guillemin, Gilles J: 5 articles (01/2009 - 01/2003)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to AIDS Dementia Complex:
1. Zidovudine (Retrovir)FDA LinkGeneric
2. Anti-Retroviral Agents (Antiretroviral Agents)IBA
3. abacavir (Ziagen)FDA Link
4. RNA (Ribonucleic Acid)IBA
5. Protons (Proton)IBA
6. N-acetylaspartate (N-acetyl aspartate)IBA
7. N-Methylaspartate (NMDA)IBA
8. Didanosine (Videx)FDA LinkGeneric
9. CreatineIBA
10. Methylphenidate (Ritalin)FDA LinkGeneric

Therapies and Procedures

1. Highly Active Antiretroviral Therapy (HAART)
2. First Aid (Aids, First)
3. Drug Therapy (Chemotherapy)
4. Art Therapy
5. Aftercare (After-Treatment)