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Imipenem

Semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains. It is stable to beta-lactamases. Clinical studies have demonstrated high efficacy in the treatment of infections of various body systems. Its effectiveness is enhanced when it is administered in combination with CILASTATIN, a renal dipeptidase inhibitor.
Also Known As:
Imipenem Anhydrous; Imipenem, Anhydrous; MK-0787; MK0787; Anhydrous Imipenem; Anhydrous, Imipenem; MK 0787; N Formimidoylthienamycin; Imipemide; N-Formimidoylthienamycin; 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 6-(1-hydroxyethyl)-3-((2-((iminomethyl)amino)ethyl)thio)-7-oxo-, (5R-(5alpha,6alpha(R*)))-
Networked: 1684 relevant articles (207 outcomes, 231 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1. Young, Katherine: 17 articles (01/2022 - 06/2017)
2. Motyl, Mary R: 11 articles (08/2021 - 07/2012)
3. Pachón, J: 11 articles (01/2016 - 04/2000)
4. Lob, Sibylle H: 10 articles (08/2021 - 06/2017)
5. Sahm, Daniel F: 10 articles (08/2021 - 06/2017)
6. Karlowsky, James A: 9 articles (04/2021 - 06/2017)
7. Pichardo, C: 9 articles (07/2011 - 04/2000)
8. Hsueh, Po-Ren: 8 articles (03/2022 - 10/2005)
9. Mainardi, Jean-Luc: 8 articles (01/2020 - 10/2007)
10. Nicolau, David P: 8 articles (01/2020 - 10/2005)

Related Diseases

1. Infections
2. Pneumonia (Pneumonitis)
3. Sepsis (Septicemia)
4. Intraabdominal Infections
5. Fever (Fevers)

Related Drugs and Biologics

1. Anti-Bacterial Agents (Antibiotics)
2. Meropenem (Merrem)
3. Ceftazidime (Fortum)
4. Amikacin (A.M.K)
5. Carbapenems (Carbapenem Antibiotics)
6. Cilastatin
7. Vancomycin
8. Ciprofloxacin (Cipro)
9. Metronidazole (Metric)
10. Tigecycline (Tygacil)

Related Therapies and Procedures

1. Therapeutics
2. Drug Therapy (Chemotherapy)
3. Length of Stay
4. Continuous Renal Replacement Therapy
5. Critical Care (Surgical Intensive Care)