alpha Subunit Glycoprotein Hormones
166
relevant articles (3 outcomes,
14 trials/studies)
found for this Bio-Agent
Description:
The alpha chain of pituitary glycoprotein hormones (THYROTROPIN; FOLLICLE STIMULATING HORMONE; LUTEINIZING HORMONE) and the placental CHORIONIC GONADOTROPIN. Within a species, the alpha subunits of these four hormones are identical; the distinct functional characteristics of these glycoprotein hormones are determined by the unique beta subunits. Both subunits, the non-covalently bound heterodimers, are required for full biologic activity.
Also Known As:
Glycoprotein Hormones, alpha Subunit; ASGPH; CG-alpha; Chorionic Gonadotropin, alpha; Chorionic Gonadotropin, alpha Subunit; Common alpha Subunit Glycoprotein Hormones; FSH-alpha; Follicle Stimulating Hormone, alpha Subunit; Genzyme Brand of Thyrotropin Alfa; Glycoprotein Hormones, alpha Chain; Glycoprotein Hormones, alpha Polypeptide; HCG-alpha; LH-alpha; Lutotropin-alpha; TSH-alpha; CG alpha; FSH alpha; HCG alpha; LH alpha; Lutotropin alpha; TSH alpha; Thyroid Stimulating Hormone, alpha Subunit; FSH, alpha Subunit; Follicle-Stimulating Hormone, alpha Subunit; HCG, alpha Subunit; Human Chorionic Gonadotropin, alpha Subunit; LH, alpha Subunit; Luteinizing Hormone, alpha Subunit; Pituitary Glycoprotein Hormone, alpha Subunit; TSH, alpha Subunit; Thyroid-Stimulating Hormone, alpha Subunit; Thyrotropin alpha Subunit
Relationship Network
Bio-Agent Context: Research Results
Experts
| 1. | Schijf, Charles P T:
1 article
(10/2005)
|
| 2. | Massuger, Leon F A G:
1 article
(10/2005)
|
| 3. | Thomas, Chris M G:
1 article
(10/2005)
|
| 4. | van Trommel, Nienke E:
1 article
(10/2005)
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| 5. | Sweep, Fred C G J:
1 article
(10/2005)
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| 6. | Gunz, G:
1 article
(07/2001)
|
| 7. | Enjalbert, A:
1 article
(07/2001)
|
| 8. | Saveanu, A:
1 article
(07/2001)
|
| 9. | Morange-Ramos, I:
1 article
(07/2001)
|
| 10. | Dufour, H:
1 article
(07/2001)
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Related Diseases
| 1. | Germ Cell and Embryonal Neoplasms (Germ Cell Tumor)
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| 2. | Hyperthyroidism
11/20/1979
- " to 13.6 ng/ml. In 7 patients with hyperthyroidism, serum levels of TSH-alpha varied from U.D. " 02/01/1994
- " Hyperthyroidism secondary to a pituitary adenoma secreting TSH, FSH, alpha-subunit and GH." 11/01/1985
- " Transsphenoidal removal of the tumour normalized serum hormones (T3, T4 free T4, TSH, alpha-subunit and Prl), and eradicated the clinical signs of hyperthyroidism and galactorrhoea. " 11/01/1984
- " A 43-yr-old woman, who had previously had a subtotal thyroidectomy, presented with hyperthyroidism and amenorrhea-galactorrhea due to a pituitary adenoma secreting TSH, TSH-alpha, and PRL. " 01/01/1988
- " A 36-year-old woman with hyperthyroidism, elevated blood thyroid-stimulating hormone (TSH) and alpha-subunit levels, amenorrhea, hyperprolactinemia and no evidence of acromegaly, was found to have a pituitary adenoma containing TSH, alpha-subunit and growth hormone by immunohistochemistry. "
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| 3. | Gestational Trophoblastic Neoplasms (Trophoblastic Neoplasms, Gestational)
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| 4. | Neoplasms (Cancer)
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| 5. | Adenoma (Adenomas)
09/01/1993
- " Tissue from 19 of the 22 clinically nonfunctioning adenomas was cultured, and concentrations of LH, FSH, alpha-subunit, and CGA were measured. " 12/01/1987
- " GH-, PRL-, TSH-, FSH-, LH-, alpha-subunit-producing adenomas, null cell adenomas and oncocytomas showed no convincing staining. " 04/01/1998
- " Although she did not have hyperprolactinemia, the in vitro culture and immunohistochemical studies revealed that the adenoma cells produced and released PRL, in addition to TSH, alpha-subunit and GH. " 08/01/1998
- " Although the number of parathyroid cells expressing hCG-alpha was in general low, the occurrence of numerous immunoreactive cells appeared to be concentrated in primary adenoma and MEN-I (20 and 33 per cent of positive cases, respectively). " 01/01/2008
- " Having segregated "intermediate-type" adenomas (26 cases), we found significant differences between typical DG-type (47 cases) and SG-type adenomas (31 cases); SG-type adenomas had younger ages (44 vs. 50), higher frequency of macroadenomas (86% vs. 58%), invasiveness (65% vs. 38%), advanced grades (3 or 4) in Knosp's classification (50% vs. 24%), and weaker immunoreaction for GH, beta-TSH, alpha-subunit, E-cadherin, and beta-catenin. "
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