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Leukotrienes

A family of biologically active compounds derived from arachidonic acid by oxidative metabolism through the 5-lipoxygenase pathway. They participate in host defense reactions and pathophysiological conditions such as immediate hypersensitivity and inflammation. They have potent actions on many essential organs and systems, including the cardiovascular, pulmonary, and central nervous system as well as the gastrointestinal tract and the immune system.
Networked: 2325 relevant articles (58 outcomes, 195 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Peters-Golden, Marc: 19 articles (12/2014 - 01/2002)
2. Haeggström, Jesper Z: 14 articles (02/2014 - 06/2002)
3. Steinhilber, Dieter: 12 articles (02/2015 - 08/2005)
4. Werz, Oliver: 11 articles (09/2014 - 08/2005)
5. Bäck, Magnus: 10 articles (02/2014 - 10/2006)
6. Henderson, William R: 10 articles (08/2013 - 01/2002)
7. Kanaoka, Yoshihide: 10 articles (05/2013 - 10/2004)
8. Holgate, S T: 10 articles (08/2008 - 06/2000)
9. Levy, Bruce D: 9 articles (02/2015 - 09/2002)
10. Serhan, Charles N: 9 articles (02/2015 - 09/2002)

Related Diseases

1. Asthma (Bronchial Asthma)
2. Inflammation
3. Urticaria (Hives)
4. Rhinitis
5. Lung Injury

Related Drugs and Biologics

1. Prostaglandins
2. zileuton (Zyflo)
3. montelukast (Singulair)
4. Leukotriene Antagonists (Leukotriene Receptor Antagonists)
5. Adrenal Cortex Hormones (Corticosteroids)
6. Thromboxanes
7. Immunoglobulin E (IgE)
8. Arachidonic Acid (Vitamin F)
9. Histamine (Histamine Dihydrochloride)
10. Leukotriene C4

Related Therapies and Procedures

1. Transplantation (Transplant Recipients)
2. Immunotherapy
3. Tourniquets
4. Ligation
5. Intravenous Infusions