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Tumor Lysis Syndrome

A syndrome resulting from cytotoxic therapy, occurring generally in aggressive, rapidly proliferating lymphoproliferative disorders. It is characterized by combinations of hyperuricemia, lactic acidosis, hyperkalemia, hyperphosphatemia and hypocalcemia.
Also Known As:
Tumour Lysis Syndrome; Syndrome, Tumor Lysis; Syndrome, Tumour Lysis; Syndromes, Tumor Lysis; Syndromes, Tumour Lysis; Tumor Lysis Syndromes; Tumour Lysis Syndromes
Networked: 510 relevant articles (27 outcomes, 19 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Hyperuricemia
2. Acute Kidney Injury (Acute Renal Failure)
3. Hematologic Neoplasms (Hematological Malignancy)
4. B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
5. Leukemia

Experts

1. Byrd, John C: 7 articles (12/2014 - 08/2003)
2. Phelps, Mitch A: 5 articles (10/2013 - 03/2009)
3. Grever, Michael R: 5 articles (10/2013 - 03/2009)
4. Darmon, Michael: 4 articles (10/2014 - 09/2008)
5. Cairo, Mitchell S: 4 articles (11/2013 - 12/2002)
6. Johnson, Amy J: 4 articles (10/2013 - 03/2009)
7. Pession, Andrea: 4 articles (08/2011 - 01/2005)
8. Kobayashi, Ryoji: 3 articles (07/2015 - 07/2005)
9. Schlemmer, Benoit: 3 articles (06/2015 - 09/2008)
10. Canet, Emmanuel: 3 articles (06/2015 - 08/2013)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Tumor Lysis Syndrome:
1. rasburicase (Elitek)FDA Link
2. Uric Acid (Urate)IBA
3. Urate Oxidase (Uricase)IBA
4. sevelamer (RenaGel)FDA Link
5. Allopurinol (Remid)FDA LinkGeneric
6. lenalidomide (CC 5013)FDA Link
7. bortezomib (Velcade)FDA Link
8. Dexamethasone (Maxidex)FDA LinkGeneric
9. Thalidomide (Thalomid)FDA Link
10. Carboplatin (JM8)FDA LinkGeneric

Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Renal Dialysis (Hemodialysis)
3. Aftercare (After-Treatment)
4. Remission Induction
5. Radiotherapy