Enzyme systems containing a single subunit and requiring only magnesium for endonucleolytic activity. The corresponding modification methylases are separate enzymes. The systems recognize specific short DNA sequences and cleave either within, or at a short specific distance from, the recognition sequence to give specific double-stranded fragments with terminal 5'-phosphates. Enzymes from different microorganisms with the same specificity are called isoschizomers. EC 220.127.116.11.
Also Known As:
Deoxyribonucleases, Type II Site-Specific; DNase, Site Specific, Type II; Deoxyribonucleases, Type II, Site Specific; Deoxyribonucleases, Type II, Site-Specific; Site-Specific DNase, Type II; Type II Site Specific DNase; Type II Site Specific Deoxyribonucleases; Type II Site-Specific DNase; Deoxyribonucleases, Type II Site Specific; Site Specific DNase, Type II; DNA Restriction Enzymes, Type II; DNase, Site-Specific, Type II; Restriction Endonucleases, Type II; Type II Restriction Enzymes