Deoxyribonuclease EcoRI (Eco RI)

One of the Type II site-specific deoxyribonucleases (EC It recognizes and cleaves the sequence G/AATTC at the slash. EcoRI is from E coliRY13. Several isoschizomers have been identified. EC 3.1.21.-.
Also Known As:
Eco RI; Eco-RI; EcoRI Endonuclease; Endodeoxyribonuclease ECoRI; Endodeoxyribonuclease HsaI; Endonuclease Eco159I; Endonuclease Eco82I; Endonuclease RsrI; Endonuclease SsoI; HsaI Endonuclease; Restriction Endonuclease RsrI; DNA Restriction Enzyme EcoRI; Deoxyribonuclease SsoI; Endonuclease EcoRI
Networked: 54 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results


1. Reich, Norbert O: 1 article (08/2004)
2. Hopkins, Ben B: 1 article (08/2004)
3. Panani, A: 1 article (03/2004)
4. Stamouli, M: 1 article (03/2004)
5. Dervenoulas, J: 1 article (03/2004)
6. Tsiotra, P: 1 article (03/2004)
7. Young, B D: 1 article (03/2004)
8. Kontsioti, F: 1 article (03/2004)
9. Bollas, G: 1 article (03/2004)
10. Pappa, V: 1 article (03/2004)

Related Diseases

1. Infection
2. Neoplasms (Cancer)
01/01/1981 - "We also demonstrate that the deletions observed on the Eco RI fragment containing the C mu gene in myeloma cells and in C mu gene-containing recombinant DNAs do not usually occur in normally differentiating B lymphocytes and are likely to be confined to myeloma tumor cells."
03/01/1987 - "Hybridization with different oncogene probes showed the presence of an human Eco RI N-ras-hybridizing fragment in the primary and secondary derived tumors, indicating that a transforming N-ras oncogene in human melanoma had been transferred to recipient cells and that transformed cells induced tumors in nude mice."
10/01/1985 - "By Southern blot analysis, the P(1)450 gene restriction patterns are similar between MOPC 41 DNA and normal mouse liver DNA digested with Eco RI, Bam HI, or Hind III, suggesting there is no evidence for a gross chromosomal rearrangement in the tumor P(1)450 gene. "
06/01/1982 - "Greater numbers of MuMTV sequences were detected in both early and late-arising mammary tumors by Eco RI restriction endonuclease mapping than were detected in tissues from uninfected BALB/c mice. "
02/01/1979 - "Since Eco RI and Bam HI cleavage of DNA from each mammary tumor generates a unique set of viral-specific fragments, we propose that the tumors are composed principally of cells derived from a subset of the many infected cells in a mammary gland; this proposal is supported by our finding that Eco RI digestion of DNA from several transplants of a primary tumor yields the pattern characteristic of the primary tumor."
3. Lymphoma (Lymphomas)
4. alpha-Thalassemia
5. Contagious Ecthyma (Orf)

Related Drugs and Biologics

1. DNA (Deoxyribonucleic Acid)
2. DNA Restriction Enzymes (Restriction Endonuclease)
3. Messenger RNA (mRNA)
4. Complementary DNA (cDNA)
5. Endonucleases
6. polyacrylamide
7. alpha-Globins
8. A-Form DNA (A-DNA)
9. RNA (Ribonucleic Acid)
10. Enzymes

Related Therapies and Procedures

1. Transplants (Transplant)