Dideoxynucleosides
27
relevant articles (1 outcomes,
1 trials/studies)
found for this Bio-Agent
Description:
Nucleosides that have two hydroxy groups removed from the sugar moiety. The majority of these compounds have broad-spectrum antiretroviral activity due to their action as antimetabolites. The nucleosides are phosphorylated intracellularly to their 5'-triphosphates and act as chain-terminating inhibitors of viral reverse transcription.
Also Known As:
ddNus; 2',3' Dideoxynucleosides; 2',3'-Dideoxynucleosides; Dideoxyribonucleosides
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Bio-Agent Context: Research Results