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Mercaptopurine (6 Mercaptopurine)

An antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with other drugs, in the treatment of or in remission maintenance programs for leukemia.
Also Known As:
6 Mercaptopurine; Purinethol; 6 Thiopurine; 1,7-Dihydro-6H-purine-6-thione; 6-Mercaptopurine Monohydrate; 6-Thiohypoxanthine; 6-Thiopurine; 6H-Purine-6-thione, 1,7-dihydro-; BW 57-323H; Leupurin; Mecaptopurine Anhydrous; Mercaptopurina Wellcome; Puri-Nethol; Purimethol; 6 Mercaptopurine Monohydrate; 6 Thiohypoxanthine; BW 57 323H; BW 57323H; 6-Mercaptopurine
Networked: 1822 relevant articles (233 outcomes, 166 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1. Schmiegelow, Kjeld: 33 articles (05/2022 - 04/2003)
2. Relling, Mary V: 21 articles (01/2022 - 01/2002)
3. Evans, William E: 19 articles (01/2022 - 01/2002)
4. Nersting, Jacob: 18 articles (01/2022 - 06/2009)
5. de Boer, Nanne K H: 16 articles (01/2022 - 04/2005)
6. Sandborn, William J: 15 articles (08/2022 - 01/2002)
7. Yang, Jun J: 14 articles (04/2022 - 04/2015)
8. Mulder, Chris J J: 13 articles (11/2021 - 01/2003)
9. Pui, Ching-Hon: 12 articles (01/2022 - 01/2002)
10. Korelitz, Burton I: 12 articles (08/2014 - 04/2003)

Related Diseases

1. Crohn Disease (Crohn's Disease)
2. Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
3. Ulcerative Colitis
4. Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
5. Leukemia

Related Drugs and Biologics

1. Azathioprine (Imuran)
2. Methotrexate (Mexate)
3. Steroids
4. Thioguanine (Tioguanine)
5. 2-mercaptopurine
6. Adrenal Cortex Hormones (Corticosteroids)
7. Immunosuppressive Agents (Immunosuppressants)
8. Prednisone (Sone)
9. Cytarabine (Cytosar-U)
10. Prodrugs

Related Therapies and Procedures

1. Therapeutics
2. Remission Induction
3. Immunomodulation
4. Maintenance Chemotherapy
5. Cranial Irradiation