Androstenediol

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71 relevant articles (7 outcomes, 4 trials/studies) found for this Bio-Agent

Description: An intermediate in TESTOSTERONE biosynthesis, found in the TESTIS or the ADRENAL GLANDS. Androstenediol, derived from DEHYDROEPIANDROSTERONE by the reduction of the 17-keto group (17-HYDROXYSTEROID DEHYDROGENASES), is converted to TESTOSTERONE by the oxidation of the 3-beta hydroxyl group to a 3-keto group (3-HYDROXYSTEROID DEHYDROGENASES).

Also Known As:

5-Androstene-3,17-diol; 5-Androstene-3beta-17beta-Diol; Androst-5-ene-3 beta,17 beta-Diol; Androst-5-ene-3,17-diol; Bisexovister; Delta 5-Androstenediol; Hermaphrodiol; Parke Davis Brand of Androstenediol; delta 5-Androstene-3 beta,17 beta-Diol; 5 Androstene 3,17 diol; 5 Androstene 3beta 17beta Diol; Androst 5 ene 3 beta,17 beta Diol; Androst 5 ene 3,17 diol; Delta 5 Androstenediol; delta 5 Androstene 3 beta,17 beta Diol; Androst-5-ene-3,17-diol, (3beta,17beta)-

Relationship Network

Bio-Agent Context: Research Results

Polycyclic Compounds: 59

4a-methylene-17-methyl-A-homo-B,19-dinorandrost-9-ene-3,17-diol

5-androstene-3 beta,17 beta-diol sulfate

Hormones, Hormone Substitutes, and Hormone Antagonists

Hormones: 46253

Gonadal Hormones: 260

Gonadal Steroid Hormones: 2275

Testosterone Congeners: 17

Androstenediol: 71

Metharmon F: 3

4a-methylene-17-methyl-A-homo-B,19-dinorandrost-9-ene-3,17-diol

5-androstene-3 beta,17 beta-diol sulfate

Experts

1.	Shimizu, Tomoharu: 7 articles (03/2007 - 08/2004)
2.	Chaudry, Irshad H: 7 articles (03/2007 - 08/2004)
3.	Choudhry, Mashkoor A: 6 articles (08/2006 - 08/2004)
4.	Bland, Kirby I: 6 articles (08/2006 - 08/2004)
5.	Szalay, Laszlo: 4 articles (04/2006 - 08/2004)
6.	Suzuki, Takao: 3 articles (08/2006 - 04/2006)
7.	Hsieh, Ya-Ching: 3 articles (08/2006 - 08/2005)
8.	Rue, Loring W: 3 articles (04/2006 - 08/2004)
9.	Loria, R M: 3 articles (09/2000 - 01/2000)
10.	Szalay, László: 2 articles (08/2006 - 07/2006)

Related Diseases

1.	Infection 09/01/1997 - "In these studies the influence of androstenediol on the course of an experimental virus infection was examined. " 01/01/2000 - "Androstenediol stimulates myelopoiesis and enhances resistance to infection in gamma-irradiated mice." 06/23/1993 - "Androstenediol regulates systemic resistance against lethal infections in mice." 01/01/1992 - "Androstenediol regulates systemic resistance against lethal infections in mice." 08/03/1999 - "Androstenediol (AED) prevents neuroendocrine-mediated suppression of the immune response to an influenza viral infection." Order ALL the reference details at left...
2.	Wounds and Injuries (Trauma) 09/01/2009 - "These findings suggest that restoration of immune regulation by androstenediol can reverse the delayed open wound contraction secondary to steroid stress." 08/01/2005 - "BACKGROUND: A recent study suggested that administration of androstenediol (Adiol) after trauma-hemorrhage (T-H) improves hepatic functions; however, the mechanism responsible for the salutary effect of Adiol remains unknown. " 07/01/2006 - "OBJECTIVE: To examine the mechanism by which androstenediol improves cardiac function following trauma-hemorrhage (T-H). " 08/01/2004 - "Salutary effects of androstenediol on cardiac function and splanchnic perfusion after trauma-hemorrhage." 09/01/2009 - "Animals that were stressed with methyl prednisolone but receiving androstenediol contracted their open wounds at faster rates compared with methyl prednisolone-stressed animals treated with the vehicle alone. " Order ALL the reference details at left...
3.	Hemorrhage 08/01/2005 - "BACKGROUND: A recent study suggested that administration of androstenediol (Adiol) after trauma-hemorrhage (T-H) improves hepatic functions; however, the mechanism responsible for the salutary effect of Adiol remains unknown. " 07/01/2006 - "OBJECTIVE: To examine the mechanism by which androstenediol improves cardiac function following trauma-hemorrhage (T-H). " 08/01/2004 - "Salutary effects of androstenediol on cardiac function and splanchnic perfusion after trauma-hemorrhage." 04/01/2006 - "Androstenediol ameliorates alterations in immune cells cytokine production capacity in a two-hit model of trauma-hemorrhage and sepsis." 08/01/2006 - "Androstenediol administration after trauma-hemorrhage attenuates inflammatory response, reduces organ damage, and improves survival following sepsis." Order ALL the reference details at left...
4.	Sepsis (Septicemia) 04/01/2006 - "Furthermore, survival rate following T-H and subsequent sepsis was improved by androstenediol treatment. " 04/01/2006 - "Since androstenediol administration following T-H attenuated cytokine production and reduced mortality in a double-hit model of T-H and sepsis, this agent appears to be a novel and useful adjunct for maintaining the immune cell functions following T-H and for decreasing the mortality rate from subsequent susceptibility to sepsis." 04/01/2006 - "Androstenediol ameliorates alterations in immune cells cytokine production capacity in a two-hit model of trauma-hemorrhage and sepsis." 08/01/2006 - "Androstenediol administration after trauma-hemorrhage attenuates inflammatory response, reduces organ damage, and improves survival following sepsis." 08/01/2006 - "Although androstenediol (adiol or 5-androstene-3beta,17beta-diol), a metabolite of dehydroepiandrosterone (DHEA), has protective effects following trauma-hemorrhage (T-H), it remains unknown whether administration of adiol has any salutary effects on the inflammatory response and outcome following a combined insult of T-H and sepsis. " Order ALL the reference details at left...
5.	Encephalitis (Encephalitis, Rasmussen) 08/14/1998 - "Increased levels of IFN-gamma in the trigeminal ganglion correlate with protection against HSV-1-induced encephalitis following subcutaneous administration with androstenediol." 03/15/1998 - "Androstenediol antagonizes herpes simplex virus type 1-induced encephalitis through the augmentation of type I IFN production." 03/15/1998 - "Dehydroepiandrosterone and androstenediol (AED) have previously been found to protect mice from viral-induced encephalitis resulting in an increased survival rate of the animals. " Order ALL the reference details at left...

Related Drugs and Biologics

1.	Dehydroepiandrosterone (DHEA)
2.	Hormones
3.	cyclosporine metabolite M17
4.	Estradiol (Estrace)
5.	Androgens
6.	Antigens
7.	Testosterone (Sustanon)
8.	Androstenedione (4 Androstene 3,17 dione)
9.	Steroids
10.	Dehydroepiandrosterone Sulfate

Related Therapies and Procedures

1.	Resuscitation
2.	Orchiectomy (Orchidectomy)
3.	Oral Administration

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