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Androstane-3,17-diol (Androstane 3,17 diol)

The unspecified form of the steroid, normally a major metabolite of TESTOSTERONE with androgenic activity. It has been implicated as a regulator of gonadotropin secretion.
Also Known As:
Androstane 3,17 diol; 5 Androstane 3,17 diol; 5 alpha-Androstane-3 alpha,17 beta-diol; 5 alpha-Androstane-3 beta,17 alpha-diol; 5 alpha-Androstane-3 beta,17 beta-diol; 5 alpha-Androstane-3alpha,17 beta-diol; 5 beta-Androstane-3 alpha,17 beta-diol; 5-Androstane-3,17-diol; 5alpha-Androstane-3beta,17alpha-diol; 5 alpha Androstane 3 alpha,17 beta diol; 5 alpha Androstane 3 beta,17 alpha diol; 5 alpha Androstane 3 beta,17 beta diol; 5 alpha Androstane 3alpha,17 beta diol; 5 beta Androstane 3 alpha,17 beta diol; 5alpha Androstane 3beta,17alpha diol
Networked: 41 relevant articles (0 outcomes, 4 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Melcangi, R C: 1 article (09/2001)
2. Magnaghi, V: 1 article (09/2001)
3. Galbiati, M: 1 article (09/2001)
4. Martini, L: 1 article (09/2001)
5. Frye, C A: 1 article (05/2000)
6. McCormick, C M: 1 article (05/2000)

Related Diseases

1. Prostatic Hyperplasia (Benign Prostatic Hyperplasia)
2. Hirsutism
3. Prostatic Neoplasms (Prostate Cancer)
08/01/1988 - "Testicular tissue obtained from ten patients orchiectomized for prostatic cancer was incubated with [3H]5 alpha-dihydrotestosterone (DHT) in order to study the metabolic transformation into 5 alpha-androstane-3 alpha,17 beta-diol (3 alpha-diol) and 5 alpha-androstane-3 beta,17 beta-diol (3 beta-diol). "
09/01/1985 - "The concentrations of testosterone, 5 alpha-dihydrotestosterone, 5 alpha-androstan-3 alpha, 17 beta-diol, 5 alpha-androstane-3 beta, 17 beta-diol, estradiol-17 beta and testosterone-glucosiduronate were measured in the plasma of the testicular vein and artery simultaneously with the estimation in peripheral venous and arterial plasma 60 min after an infusion of 3000 micrograms dihydrotestosterone (DHT) or estradiol (E2), respectively, in patients undergoing orchiectomy for prostatic cancer. "
01/01/1981 - "Serum levels of testosterone (T), dihydrotestosterone (DHT), androsterone (A), 5 alpha-androstane-3 alpha, 17 beta-diol (5 alpha-diol) and estradiol-17 beta (E2) were measured by radioimmunoassay in the sera of 9 patients with untreated prostatic cancer and in 11 with benign prostatic hypertrophy (BPH). "
04/01/1982 - "By means of specific radioimmunoassays unconjugated testosterone, 5 alpha-dihydrotestosterone, 5 alpha-androstane-3 alpha, 17 beta-diol, 5 alpha-androstane-3 beta, 17 beta-diol and estradiol-17 beta as well as testosterone-glucosiduronate were estimated in the plasma of the spermatic vein and artery simultaneously with the determination in peripheral venous and arterial plasma in ten male patients undergoing orchiectomy for prostatic cancer. "
01/01/1988 - "Total tissue content and subcellular distribution of DHEA sulfate, DHEA, androst-5-ene-3 beta,17 beta-diol, androst-4-ene-3,17-dione, testosterone, 5 alpha-DHT, and 5 alpha-androstane-3 alpha,17 beta-diol as well as the activities of steroid sulfate-sulfatase, 17 beta-hydroxysteroid dehydrogenase, 5 alpha-reductase, 3 alpha/beta-hydroxysteroid dehydrogenase, and creatine kinase were quantified in 12 untreated primary tumors of prostatic cancer. "
4. Seizures (Seizure)
5. Neoplasms (Cancer)

Related Drugs and Biologics

1. Androstane-3,17-diol (Androstane 3,17 diol)
2. Testosterone (Sustanon)
3. Dihydrotestosterone (Androstanolone)
4. Estradiol (Estrace)
5. Androstenedione (4 Androstene 3,17 dione)
6. Progesterone
7. Dehydroepiandrosterone (DHEA)
8. Androsterone
9. Cholestenone 5 alpha-Reductase (5 alpha-Reductase)
10. 17-alpha-Hydroxyprogesterone (17 Hydroxyprogesterone)

Related Therapies and Procedures

1. Orchiectomy (Orchidectomy)
2. Injections
3. Castration