An antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids. It acts by interfering with the enzymatic steps involved in the conversion of acetate to hydroxymethylglutaryl coenzyme A as well as inhibiting the activity of HYDROXYMETHYLGLUTARYL COA REDUCTASES which is the rate limiting enzyme in the biosynthesis of cholesterol.
Also Known As:
3-Hydroxy-3-methylpentanedioic Acid; beta-Hydroxy-beta-Methylglutarate; 3 Hydroxy 3 methylglutaric Acid; 3 Hydroxy 3 methylpentanedioic Acid; Acid, 3-Hydroxy-3-methylglutaric; Acid, 3-Hydroxy-3-methylpentanedioic; beta Hydroxy beta Methylglutarate; 3-Hydroxy-3-methylglutaric Acid; Pentanedioic acid, 3-hydroxy-3-methyl-
Networked: 9 relevant articles (1 outcomes, 0 trials/studies)

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Bio-Agent Context: Research Results

Related Diseases

1. Hyperlipidemias (Hyperlipidemia)
2. Atherosclerosis
3. Gallstones (Gallstone)
4. Hyperammonemia
5. Hyperlipoproteinemia Type II (Familial Hypercholesterolemia)

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