|1.||Silverman, Robert H: 5 articles (06/2012 - 02/2005)|
|2.||De Meirleir, Kenny: 5 articles (02/2007 - 01/2003)|
|3.||Frenkiel, Marie-Pascale: 3 articles (08/2011 - 06/2003)|
|4.||Desprès, Philippe: 3 articles (08/2011 - 06/2003)|
|5.||Williams, Bryan R G: 3 articles (08/2006 - 02/2005)|
|6.||Nijs, Jo: 3 articles (11/2005 - 01/2003)|
|7.||Englebienne, Patrick: 3 articles (06/2005 - 01/2003)|
|8.||Song, Cuiping: 2 articles (12/2014 - 05/2014)|
|9.||Cheng, Anchun: 2 articles (12/2014 - 05/2014)|
|10.||Ding, Chan: 2 articles (12/2014 - 05/2014)|
|1.||Chronic Hepatitis C
05/01/1997 - "Serum 2',5'-oligoadenylate synthetase concentrations in acute and chronic hepatitis C."
10/01/1993 - "It was our aim to evaluate whether the baseline activity of 2-5 oligoadenylate synthetase (2-5 OAS) in serum and changes induced by the treatment with interferon are relevant factors in remission of chronic hepatitis C. "
02/01/1996 - "Effect of alpha interferon (IFN-alpha) on 2'-5' oligoadenylate synthetase activity in peripheral blood mononuclear cells of patients with chronic hepatitis C: relationship to the antiviral effect of IFN-alpha."
10/01/1995 - "Activity of the interferon-induced 2',5'-oligoadenylate synthetase in patients with chronic hepatitis C."
12/01/1994 - "Longitudinal changes in lymphocyte subpopulations, including total and activated T cells, B cells, and NK cells as well as NK activity and 2',5'-oligoadenylate synthetase (2'5' AS) levels were determined in peripheral blood before, during, and after therapy with human recombinant interferon-alpha (HurIFN-alpha) in 39 patients with serologically and biopsy-confirmed chronic hepatitis C. "
01/01/1989 - "In acute hepatitis patients, an early but transient elevation of 2',5'-oligoadenylate synthetase was observed; the mean level at 1 week was significantly greater than the mean level at 4 weeks after the onset of their illness (p less than 0.01). "
05/01/1997 - "Serum 2',5'-oligoadenylate synthetase concentration in the acute stage of hepatitis was above 200 pmol/dL in all four patients who recovered and in only of two of the remaining 10 patients (p < 0.02, Fisher's exact test). "
06/01/1991 - "[2'-5' oligoadenylate synthetase activity in patients with acute viral hepatitis and chronic type B hepatitis, and its clinical significance]."
04/01/1991 - "Persistent detection of raised 2',5' oligoadenylate synthetase activity levels during the acute stage of non-A, non-B hepatitis may thus be an indicator of progression of the disease."
04/01/1991 - "We measured the sequential changes in 2',5' oligoadenylate synthetase activity in 21 patients with acute viral hepatitis (5 with type A, 6 with type B, and 10 with type non-A, non-B hepatitis) by radioimmunoassay. "
|3.||Systemic Lupus Erythematosus (Libman-Sacks Disease)
06/01/1983 - "The interferon (IFN)-induced enzyme 2-5A synthetase was elevated in mononuclear cells from both serum IFN-positive and -negative systemic lupus erythematosus (SLE) patients. "
03/01/1986 - "Spontaneous production of the interferon induced enzyme 2',5'-oligoadenylate synthetase (2',5'-A synthetase) was significantly greater in blood lymphocytes of patients with systemic lupus erythematosus (SLE), Behçet's syndrome, and rheumatoid arthritis than in control lymphocytes. "
08/01/2012 - "Previous studies in mice identified the 2'-5' oligoadenylate synthetase 1b (Oas1b) gene as a determining factor for resistance to WNV infection. "
11/01/2010 - "Subsequent study revealed that HCV infection induces IFN-stimulated response element activation, as evidenced by upregulation of 2',5'-oligoadenylate synthetase 1. However, nuclear translocation of IRF-7 was impaired following HCV infection. "
06/01/1996 - "Freshly explanted liver cells and peripheral blood mononuclear cells (PBMC) from 80 patients with chronic HCV infection were used to study the capacity of IFN to induce the enzyme 2',5'-oligoadenylate synthetase (2'5'-AS) in vitro. "
01/01/2015 - "Moreover, IFN-mediated signalling pathways (IFN, STAT1 and the 2',5'-oligoadenylate synthetase) were activated during PSaV infection. "
06/01/2013 - "Therefore, BVDV may be a cause of early embryonic or feotal loss in early pregnant cows and serum 2-5A synthetase may be useful as an indicator of viral infection in cows."
|2.||Interferon-alpha (Interferon Alfa)
|3.||Messenger RNA (mRNA)
|4.||Proteins (Proteins, Gene)
|6.||Hepatitis B e Antigens
|10.||Bile Acids and Salts (Bile Acids)